Results 111 to 120 of about 847,836 (355)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Studies of Thyroid Hormones (Propylthiouracil and L-Thyroxine) Interaction with Human Serum Albumin-Spectroscopic Approach [PDF]

, 2023
Israa Ismail Abu Katteh, Husain Alsamamra, Musa Mahmoud Abu Teir   +2 more
openalex   +1 more source

Longitudinal evaluation of aflatoxin exposure in two cohorts in south-western Uganda [PDF]

, 2015
Aflatoxins (AF) are a group of mycotoxins. AF exposure causes acute and chronic adverse health effects such as aflatoxicosis and hepatocellular carcinoma in human populations, especially in the developing world.
Allan Nkwata, Alpert ME, Busby WF, David Serwadda, Fred Nalugoda, Gershim Asiki, Guoqing Qian, Huang J, Janet Seeley, Jia-Sheng Wang, John Ssempebwa, Jonathan H. William, Kaaya AN, Kathy Xue, Lili Tang, Min-Su Kang, Mukwaya P, Ofori-Adjei D, Peter Nkurunziza, Pontiano Kaleebu, Qian G, Richard Muwanika, Robert Newton, Romanik CT, Shirima CP, Shuaib FM, Tom Lutalo, Wang JS, Wang JS, Wang JS, Wild CP, Williams JH, Xiao Song   +32 more
core   +1 more source

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

Advanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco, Valerio Francesco Annese, Valerio Galli, Ilaria Penna, Debora Russo, Marina Veronesi, Rita Scarpelli, Stefania Sabella, Mario Caironi   +8 more
wiley   +1 more source

Insights into the binding of buspirone to human serum albumin using multi-spectroscopic and molecular docking techniques

Heliyon
Buspirone is an anxiolytic drug that plays a significant role in managing anxiety disorders and alleviating their symptoms as well. Several techniques were utilized to study the interaction between buspirone and human serum albumin under physiological ...
Javad Sargolzaei, Elaheh Jalali, Parisa Rajabi   +2 more
doaj   +1 more source

Self-Assembly of Human Serum Albumin: A Simplex Phenomenon

Biomolecules, 2017
Spontaneous self-assemblies of biomolecules can generate geometrical patterns. Our findings provide an insight into the mechanism of self-assembled ring pattern generation by human serum albumin (HSA). The self-assembly is a process guided by kinetic and
Garima Thakur, Kovur Prashanthi, Keren Jiang, Thomas Thundat   +3 more
doaj   +1 more source

PENGARUH PEMBERIAN SUPLEMENTASI SUPEROXIDE DISMUTASE (SOD) TERHADAP KADAR ALBUMIN SERUM PADA LANSIA [PDF]

, 2015
Background: Levels of serum albumin can be used as a predictor of morbidity and mortality in the elderly. Reduced serum albumin concentration can be caused by oxidative modification due to aging or insufficient protein intake.
Nalaresi, Andyta, Ngestiningsih, Dwi, Setyawati, Amalia N   +2 more
core  

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Study of interaction between nicotinamide and human serum albumin using spectroscopic techniques and molecular docking simulation simulation

یافته‌های نوین در علوم زیستی, 2022
Human serum albumin is one of the most important blood proteins that has the ability to bind a wide range of compounds and different drugs. Hence, knowing how drugs bind to albumin is crucial to understand their pharmacokinetics and pharmacodynamic ...
Golnaz Parvizi Fard, Lale Solouki, Mostafa Zakariazadeh, Hossein Haghaei, Somaieh Soltani   +4 more
doaj  

Low-temperature specific heat of a globular protein: human serum albumin [PDF]

, 1984
B. I. Verkin, Yu. P. Blagoı̆, A. M. Gurevich, V. N. Eropkin   +3 more
openalex   +1 more source