Results 11 to 20 of about 976,647 (347)
An epigenetic clock for human skeletal muscle [PDF]
Journal of Cachexia, Sarcopenia and Muscle, 2019 Background Ageing is associated with DNA methylation changes in all human tissues, and epigenetic markers can estimate chronological age based on DNA methylation patterns across tissues.
Sarah Voisin +15 more
semanticscholar +8 more sources
Selection and identification of a novel ssDNA aptamer targeting human skeletal muscle
Bioactive Materials, 2023 Skeletal muscle disorders have posed great threats to health. Selective delivery of drugs and oligonucleotides to skeletal muscle is challenging. Aptamers can improve targeting efficacy.
Shuming Sun +11 more
doaj +1 more source
Protein profile of fiber types in human skeletal muscle: a single-fiber proteomics study
Skeletal Muscle, 2021 Human skeletal muscle is composed of three major fiber types, referred to as type 1, 2A, and 2X fibers. This heterogeneous cellular composition complicates the interpretation of studies based on whole skeletal muscle lysate.
M. Murgia +5 more
semanticscholar +1 more source
New Perspectives for Postmortem Human Satellite Cells of Different Embryological Origin
Frontiers in Physiology, 2022 Human postmortem skeletal muscles are a unique source of satellite cells for skeletal muscle regenerative studies. Presomite and somite satellite cells obtained by postmortem muscles have been established as populations of human skeletal muscle precursor
Tiziana Pietrangelo +19 more
doaj +1 more source
Anserine is expressed in human cardiac and skeletal muscles
Physiological Reports, 2023 We evaluated whether anserine, a methylated analog of the dipeptide carnosine, is present in the cardiac and skeletal muscles of humans and whether the CARNMT1 gene, which encodes the anserine synthesizing enzyme carnosine‐N‐methyltransferase, is ...
Lívia deSouza Gonçalves +9 more
doaj +1 more source
Human skeletal muscle biochemical diversity [PDF]
Journal of Experimental Biology, 2012 SUMMARY The molecular components largely responsible for muscle attributes such as passive tension development (titin and collagen), active tension development (myosin heavy chain, MHC) and mechanosensitive signaling (titin) have been well studied in animals but less is known about their roles in humans.
Timothy F, Tirrell +5 more
openaire +3 more sources
Defining the Skeletal Myogenic Lineage in Human Pluripotent Stem Cell-Derived Teratomas
Cells, 2022 Skeletal muscle stem cells are essential to muscle homeostasis and regeneration after injury, and have emerged as a promising cell source for treating skeletal disorders.
Matthew P. Pappas +3 more
doaj +1 more source
Lactate-induced lactylation in skeletal muscle is associated with insulin resistance in humans
Frontiers in Physiology, 2022 Elevated circulating lactate has been associated with obesity and insulin resistance. The aim of the current study was to determine if lactate-induced lysine lactylation (kla), a post-translational modification, was present in human skeletal muscle and ...
Dominic Maschari +7 more
doaj +1 more source
Single-cell transcriptional profiles in human skeletal muscle
Scientific Reports, 2020 Skeletal muscle is a heterogeneous tissue comprised of muscle fiber and mononuclear cell types that, in addition to movement, influences immunity, metabolism and cognition.
A. Rubenstein +12 more
semanticscholar +1 more source
Leptin receptors in human skeletal muscle [PDF]
The FASEB Journal, 2007 The aim of this study was to determine if leptin receptors (OB‐R) are expressed at the protein level in human skeletal muscle. Muscle biopsies were obtained from the musculus vastus lateralis in fourteen, healthy men (age = 33.1 ± 2 yr, height = 175.9 ± 1.7 cm, body mass = 81.2 ± 3.8 kg, body fat = 22.5 ± 1.9%).
Guerra, Borja +6 more
openaire +5 more sources