Recent Trends in Biofabrication Technologies for Studying Skeletal Muscle Tissue-Related Diseases
Frontiers in Bioengineering and Biotechnology, 2021 In native skeletal muscle, densely packed myofibers exist in close contact with surrounding motor neurons and blood vessels, which are embedded in the fibrous connective tissue.
Seungyeun Cho +4 more
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Human Skeletal Muscle Fiber Type Classifications [PDF]
Physical Therapy, 2001 Human skeletal muscle is composed of a heterogenous collection of muscle fiber types.1–3 This range of muscle fiber types allows for the wide variety of capabilities that human muscles display. In addition, muscle fibers can adapt to changing demands by changing size or fiber type composition.
W, Scott +2 more
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Enhancement of K+ conductance improves in vitro the contraction force of skeletal muscle in hypokalemic periodic paralysis [PDF]
, 1990 An abnormal ratio between Na+ and K+ conductances seems to be the cause for the depolarization and paralysis of skeletal muscle in primary hypokalemic periodic paralysis.
Ballanyi +19 more
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Calsequestrins in skeletal and cardiac muscle from adult Danio rerio [PDF]
, 2015 Calsequestrin (Casq) is a high capacity, low affinity Ca2+-binding protein, critical for Ca2+-buffering in cardiac and skeletal muscle sarcoplasmic reticulum. All vertebrates have multiple genes encoding for different Casq isoforms.
Argenton, Francesco +6 more
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RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca2+ assays. [PDF]
, 2020 Elevated cytoplasmic [Ca2+] is characteristic in severe skeletal and cardiac myopathies, diabetes, and neurodegeneration, and partly results from increased Ca2+ leak from sarcoplasmic reticulum stores via dysregulated ryanodine receptor (RyR) channels ...
Bers, Donald M +6 more
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Human cachexia induces changes in mitochondria, autophagy and apoptosis in the skeletal muscle [PDF]
, 2019 Cachexia is a wasting syndrome characterized by the continuous loss of skeletal muscle mass due to imbalance between protein synthesis and degradation, which is related with poor prognosis and compromised quality of life.
Alcantara, P. S. +9 more
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Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy
Journal of Cachexia, Sarcopenia and Muscle, 2022 Human pluripotent stem cell‐derived muscle models show great potential for translational research. Here, we describe developmentally inspired methods for the derivation of skeletal muscle cells and their utility in skeletal muscle tissue engineering with
M. Shahriyari +21 more
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Detection of chromosomal regions showing differential gene expression in human skeletal muscle and in alveolar rhabdomyosarcoma [PDF]
, 2004 BACKGROUND: Rhabdomyosarcoma is a relatively common tumour of the soft tissue, probably due to regulatory disruption of growth and differentiation of skeletal muscle stem cells.
Bisognin, Andrea +2 more
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A ribonuclease from human skeletal muscle [PDF]
Biochemical Journal, 1970 1. A ribonuclease has been prepared from human muscle by ammonium sulphate fractionation, heat treatment and ion-exchange chromatography. 2. The enzyme degrades polycytidylic acid and polyuridylic acid to the nucleoside 3′-phosphates, with nucleoside 2′:3′-cyclic phosphates as intermediates. Polyadenylic acid and polyguanylic acid are not attacked.
D F, Goldspink, R J, Pennington
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Molecular Metabolism, 2020 Objective: Estrogen receptor-α (ERα) is a nuclear receptor family member thought to substantially contribute to the metabolic regulation of skeletal muscle.
Melissa R. Iñigo +25 more
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