Results 61 to 70 of about 23,287 (168)

Human leucocyte antigen and human T‐cell lymphotropic virus type 1 associated diseases in Brazil [PDF]

British Journal of Haematology, 2003
Universidade Federal de Sao Paulo, Escola Paulista Med, Hematol & Transfus Med Serv, Sao Paulo ...
Davimar Miranda, Borducchi, Maria, Gerbase-DeLima, Andrey, Morgun, Natalia, Shulzhenko, Maria S, Pombo-de-Oliveira, José, Kerbauy, José Salvador, Rodrigues de Oliveira   +6 more
openaire   +2 more sources

Human T-cell lymphotropic virus type 1-related uveitis, review about a case

The Pan-American Journal of Ophthalmology
Human T-cell lymphotropic virus type 1 (HTLV-1) is an endemic retrovirus associated with adult T-cell leukemia/lymphoma (ATL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM-TSP), and HTLV-1 uveitis (HU).
Margarida Baptista, Carolina Bruxelas, Miguel Cordeiro, Marta Guedes   +3 more
doaj   +1 more source

Molecular and Phylogenetic Characterization of HTLV‐1 Infection in Patients With Hematological Malignancies in the State of Pará, Northern Brazil

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT Human T‐lymphotropic viruses 1 and 2 (HTLV‐1 and HTLV‐2) were first isolated from patients with hematological malignancies. This study was the first to investigate the frequency of HTLV‐1 and its molecular diversity among patients with hematolymphoid cancers who were treated at a leading reference hospital in Pará, northern Brazil.
Gabriel dos Santos Pereira Neto, Ana Vilhena Alves, Bruno José Sarmento Botelho, Andrio Silva da Silva, Debora Monteiro Carneiro, Rommel Mario Rodriguez Burbano, Ricardo Ishak, Antonio Carlos Rosário Vallinoto, Izaura Maria Vieira Cayres Vallinoto   +8 more
wiley   +1 more source

How the DNA damage response determines the fate of HTLV-1 Tax-expressing cells

Retrovirology, 2012
How the Human T lymphotropic virus type 1 (HTLV-1) Tax protein stimulates proliferation while triggering cell cycle arrest and senescence remains puzzling.
Boxus Mathieu, Willems Luc
doaj   +1 more source

Distribution of adult T‐cell leukaemia/lymphoma subtypes and survival outcomes across geographical regions: An international retrospective cohort study

British Journal of Haematology, Volume 209, Issue 1, Page 107-115, July 2026.
Summary Although adult T‐cell leukaemia/lymphoma (ATL) has a higher burden in certain world regions, outcomes have not been directly compared across regions. We conducted a multicentre cohort study comparing the distribution of ATL subtypes and overall survival (OS) across 1090 adults (≥18 years) diagnosed with ATL during 2000–2023 in Japan (n = 366 ...
Bryan Valcarcel, Atae Utsunomiya, Maki Otsuka, Masaharu Miyahara, Kenji Ishitsuka, Yasushi Takamatsu, Junji Suzumiya, Kazuo Tamura, Jule F. Vasquez, Daniel Enriquez‐Vera, Brady E. Beltran, Denisse Castro, Thanya Runciman, Henry Idrobo, Elizabeth Arrieta, Oriana Arias, Eduardo Gotuzzo, Gabriela Garrido‐Pinzás, Victor Rivera, Daniel La Rosa, Camila Peña, Lorena Fiad, Juan C. Ramos, Jose Sandoval‐Sus, Alejandro Sica, Britney N. Bell, Lucy B. Cook, Veronica Leataud, Eliana C. M. Miranda, Carlos Chiattone, Hiroo Katsuya, Luis Malpica   +31 more
wiley   +1 more source

HTLV-1 ORF-I Encoded Proteins and the Regulation of Host Immune Response: Viral Induced Dysregulation of Intracellular Signaling

Journal of Immunology Research, 2015
The human T-cell lymphotropic virus type 1 (HTLV-1) is a retrovirus associated with both proliferative and inflammatory disorders. This virus causes a persistent infection, mainly in CD4+ T lymphocyte.
Carolina Rosadas, Marzia Puccioni-Sohler
doaj   +1 more source

From Immunodeficiency to Humanization: The Contribution of Mouse Models to Explore HTLV-1 Leukemogenesis

Viruses, 2015
The first discovered human retrovirus, Human T-Lymphotropic Virus type 1 (HTLV-1), is responsible for an aggressive form of T cell leukemia/lymphoma.
Eléonore Pérès, Eugénie Bagdassarian, Sébastien This, Julien Villaudy, Dominique Rigal, Louis Gazzolo, Madeleine Duc Dodon   +6 more
doaj   +1 more source

Triple‐Mutated HSV‐1 Expressing Soluble B7‐1 Plus CTLA‐4 Blockade Suppresses Lymph Node Metastasis in Tongue Cancer

Cancer Science, Volume 117, Issue 7, Page 1961-1974, July 2026.
In murine tongue cancer models, T‐mB7‐1, a triple‐mutated oncolytic herpes simplex virus type 1 (HSV‐1) engineered to express soluble B7‐1, suppresses cervical lymph node metastasis and improves survival, addressing a major prognostic determinant in oral squamous cell carcinoma (OSCC).
Akinari Sugauchi, Toshihiro Uchihashi, Hirotaka Ito, Miwako Iwai, Yuzuri Tsurumaki Sato, Kyoko Kurioka, Sena Zeynep Usta, Minoru Tanaka, Mikihiko Kogo, Susumu Tanaka, Hiroshi Fukuhara, Tomoki Todo   +11 more
wiley   +1 more source

Global Dynamics of an HTLV-1 Model with Cell-to-Cell Infection and Mitosis

Abstract and Applied Analysis, 2014
A mathematical model of human T-cell lymphotropic virus type 1 in vivo with cell-to-cell infection and mitosis is formulated and studied. The basic reproductive number R0 is derived.
Sumei Li, Yicang Zhou
doaj   +1 more source

Rare antigen‐negative red blood cells from pluripotent stem cells for precision transfusion medicine

Transfusion, Volume 66, Issue 7, Page 1257-1264, July 2026.
Abstract Background Blood bank identification of antibodies against high‐prevalence antigens remains a challenge due to the scarcity of antigen‐negative reagent red cells sourced from blood donors. The MAM antigen, encoded by EMP3, is one such antigen associated with red cell alloimmunization and hemolytic disease of the fetus and newborn. Study Design
Naomi Gunawardena, Hyun Hyung An, Randall W. Veliquette, Edmund Carvalho, Sambit Dalui, Kaoru Takasaki, Eric Wafula, Deborah L. French, Giulia Pavani, Stella T. Chou   +9 more
wiley   +1 more source