Results 71 to 80 of about 23,287 (168)

Global Consultation for Clinical Xenotransplantation: International Xenotransplantation Association Consensus and Communiqué Update

Xenotransplantation, Volume 33, Issue 4, July/August 2026.
ABSTRACT Xenotransplantation has entered a phase of accelerated clinical translation, necessitating renewed international consensus on governance, ethics, safety, and regulatory oversight. In September 2025, the International Xenotransplantation Association (IXA), in partnership with The Transplantation Society (TTS) and with engagement from the World ...
Wayne J. Hawthorne, Eckhard Wolf, Peter J. Cowan, Wei Wang, Ik Jin Yun, Paolo Brenner, Greg Korbutt, Raphael P. H. Meier, Megan Sykes, Léo H. Bühler, Linda Scobie, Olga Garkavenko, Hyunil Kim, Daniel J. Hurst, Richard N. Pierson III, Robert Rieben, Manuel Pascual, Nicole Scholes‐Robertson, Emanuele Cozzi, Adrián Abalovich, Alexandre Loupy, Hidetaka Hara, Rita Bottino, Burcin Ekser, Muhammad M. Mohiuddin, Jay Fishman   +25 more
wiley   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, Volume 13, Issue 35, 24 June 2026.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

New RHCE*cE allele with c.872C>G and variable RH3 and RH4 phenotypes, predicted to encode p.Pro291Arg

Transfusion, Volume 66, Issue 8, Page 1707-1709, August 2026.
Evelyne Heng, Gabriel Neto Braga, Marine Branger, Mylene Flammang, Christophe Tournamille, Aline Floch   +5 more
wiley   +1 more source

Upregulation of hsa-miR-125b in HTLV-1 asymptomatic carriers and HTLV-1-associated myelopathy/tropical spastic paraparesis patients

Memorias do Instituto Oswaldo Cruz, 2012
The retrovirus human T lymphotropic virus type 1 (HTLV-1) promotes spastic paraparesis, adult T cell leukaemia and other diseases. Recently, some human microRNAs (miRNAs) have been described as important factors in host-virus interactions.
Larissa Deadame de Figueiredo Nicolete, Roberto Nicolete, Rodrigo Haddad, Rochele Azevedo, Fabíola Attié de Castro, Yuetsu Tanaka, Osvaldo Massaiti Takayanagui, Dimas Tadeu Covas, Simone Kashima   +8 more
doaj   +1 more source

Re-mapping the molecular features of the human immunodeficiency virus type 1 and human T-cell lymphotropic virus type 1 Brazilian sequences using a bioinformatics unit established in Salvador, Bahia, Brazil, to give support to the viral epidemiology studies

Memorias do Instituto Oswaldo Cruz, 2007
The analysis of genetic data for human immunodeficiency virus type 1 (HIV-1) and human T-cell lymphotropic virus type 1 (HTLV-1) is essential to improve treatment and public health strategies as well as to select strains for vaccine programs.
Artur Trancoso Lopo de Queiroz, Aline Cristina Andrade Mota-Miranda, Tulio de Oliveira, Domingos Ramon Moreau, Caroline de Carvalho Urpia, Chandra Mara Carvalho, Bernardo Galvão-Castro, Luiz Carlos Junior Alcantara   +7 more
doaj  

Infective dermatitis associated with human T-cell lymphotropic virus type-1, an underdiagnosed disease

International Journal of Infectious Diseases
Infective dermatitis associated with human T-cell lymphotropic virus type-1 (HTLV-1) (IDH) is a severe form of chronically infected eczema occurring in early childhood, although very rarely cases have been reported in adults.
A.L. Bittencourt, L. Farre
doaj   +1 more source

Overview on HTLV-I p12, p8, p30, p13: accomplices in persistent infection and viral pathogenesis.

Frontiers in Microbiology, 2012
The human T-lymphotropic virus type-1 (HTLV-1) is etiologically linked to adult T-cell leukemia/lymphoma (ATLL) and tropical spastic paraparesis/ HTLV-1 associated myelopathy (TSP/HAM).
Christophe eNicot, xue tao ebai
doaj   +1 more source

Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival

Retrovirology, 2007
Background Human T-lymphotropic virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma and is linked to a number of lymphocyte-mediated disorders. HTLV-1 contains both regulatory and accessory genes in four pX open reading frames.
Silverman Lee, Datta Antara, Phipps Andrew J, Hiraragi Hajime, Ratner Lee, Lairmore Michael D   +5 more
doaj   +1 more source

The Clinical Pathway of Human T-Lymphotropic Virus Type-1 (HTLV-1) from Infection to Leukemia: A Comprehensive Review

Experimed
Human T-lymphotropic virus type 1 (HTLV-1), a member of the Retroviridae family, is a pathogenic retrovirus that primarily includes two clinically relevant types: HTLV-1 and HTLV-2. HTLV-1 is etiologically linked to adult T-cell leukemia/lymphoma (ATLL),
Zahra Ghahremani, Kosar Hosseini-karkaj, Mehrdad Pashazadeh, Abolfazl Jafarı-sales, Aylin Golestani, Kosar Soleymanpour, Hossein Bannazadeh Baghi, Parya Rouhi, Mohaddeseh Bahmani   +8 more
doaj   +1 more source

Molecular Mechanisms of HTLV-1 Cell-to-Cell Transmission

Viruses, 2016
The tumorvirus human T-cell lymphotropic virus type 1 (HTLV-1), a member of the delta-retrovirus family, is transmitted via cell-containing body fluids such as blood products, semen, and breast milk.
Christine Gross, Andrea K. Thoma-Kress
doaj   +1 more source