Results 91 to 100 of about 38,215 (244)

Infection with human T-lymphotropic virus types-1 and -2 (HTLV-1 and -2): Implications for blood transfusion safety [PDF]

Transfusion Clinique et Biologique, 2016
Many countries currently perform antibody screening for HTLV-1 infection in blood donors, and this intervention is likely cost-effective in preventing HTLV-1 related diseases in high prevalence countries. However, a number of high-income countries with low prevalence of HTLV-1 infection also perform universal HTLV-1 screening and debate has arisen ...
openaire   +4 more sources

High Frequencies of Functionally Competent Circulating Tax-Specific CD8+ T Cells in Human T Lymphotropic Virus Type 2 Infection [PDF]

The Journal of Immunology, 2009
Abstract Human T lymphotropic virus type 2 (HTLV-2) is characterized by a clinically asymptomatic persistent infection in the vast majority of infected individuals. In this study, we have characterized for the first time ex vivo specific CTL responses against the HTLV-2 Tax protein. We could detect CTL responses only against a single HLA-
André L A, Oliveira, Hitoshi, Hayakawa, Doris, Schor, Ana Claudia C B, Leite, Otávio M, Espíndola, Allison, Waters, Jonathan, Dean, Derek G, Doherty, Abelardo Q-C, Araújo, William W, Hall   +9 more
openaire   +2 more sources

Effect of pulsed methylprednisolone on pain, in patients with HTLV-1-associated myelopathy [PDF]

, 2016
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is an immune mediated myelopathy caused by the human T-lymphotropic virus type 1 (HTLV-1). The efficacy of treatments used for patients with HAM/TSP is uncertain.
Adonis, A, Buell, KG, Demontis, MA, Dhasmana, D, Haddow, J, Martin, F, Puri, A, Short, CL, Taylor, GP   +8 more
core   +1 more source

Differential regulation of translational stress responses by herpesvirus ubiquitin deconjugases

The FEBS Journal, EarlyView.
Translating viral mRNAs is challenging due to structural features that may slow translation or induce ribosome stalling. The viral ubiquitin deconjugases encoded by human pathogenic herpesviruses regulate the cellular response to ribosomal stress by inhibiting various branches of the Ribosomal Quality Control (RQC) and activating Ribosomal Stress ...
Jiangnan Liu, Noemi Nagy, Carlos Mario Ayala‐Torres, Maria G. Masucci   +3 more
wiley   +1 more source

Laboratory Abnormalities in Former Blood Donors Seropositive for Human T-Lymphotropic Virus Types 1 and 2

Archives of Pathology & Laboratory Medicine, 2000
Abstract Context.—The human T-lymphotropic viruses types 1 and 2 (HTLV-1 and HTLV-2) are highly prevalent among injection drug users in the United States. However, the clinical course of infection has not been well characterized. Objective.—To understand HTLV-1–and HTLV-2–associated laboratory abnormalities, which may ...
Simone A. Glynn, Edward L. Murphy, David J. Wright, Ronald A. Sacher, Joy Fridey, George B. Schreiber   +5 more
openaire   +1 more source

Metagenomic identification of human Gemykibivirus-2 (HuGkV-2) in parenterally infected blood donors from the Brazilian Amazon

International Journal of Infectious Diseases, 2020
Objectives: To metagenomically analyse blood units originating from the Brazilian Amazon and positive for parenterally transmitted infections (human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), human T-lymphotropic ...
Rafael S. Bezerra, Hellen T. Bitencourt, Dimas T. Covas, Simone Kashima, Svetoslav N. Slavov   +4 more
doaj   +1 more source

Prevalence of Human T-Lymphotropic Virus Types I and II in Patients With Hematological Disorders in Isfahan, Iran [PDF]

, 2015
Background: Human T-cell lymphotropic virus types I and II (HTLV-I and HTLV-II) are deltaretroviruses which may cause leukemia, lymphoma and HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Ghorani, Mohammadreza., Karimi, Ali., Mahzoonieh, Mohamad Reza., Nikoozad, Razieh., Pourgheysari, Batoul.   +4 more
core   +3 more sources

Perceptions of donor screening—Do I always need to tell the truth?

Transfusion Medicine, EarlyView.
Abstract Background The Donor Health Assessment Questionnaire (DHQ) is fundamental to blood safety. We describe attitudes towards truthfulness among first‐time donors who tested positive for transfusion transmissible infections and those who did not.
Sheila F. O'Brien, Lori Osmond, Mindy Goldman   +2 more
wiley   +1 more source

Clinical Outcomes and Disease Progression among Patients Coinfected with HIV and Human T Lymphotropic Virus Types 1 and 2 [PDF]

Clinical Infectious Diseases, 2004
The goal of this study was to investigate clinical outcomes and survival probabilities among persons coinfected with human immunodeficiency virus (HIV) and human T lymphotropic viruses types 1 and 2 (HTLV-I/II). A nonconcurrent cohort study of 1033 HIV-infected individuals was also conducted.
Mark A, Beilke, Katherine P, Theall, Megan, O'Brien, John L, Clayton, Stephanie M, Benjamin, Elsa L, Winsor, Patricia J, Kissinger   +6 more
openaire   +2 more sources

Adult T‐cell leukemia/lymphoma in French Guiana (1990–2019): Epidemiology, clinical features, and HTLV‐1 genetic diversity in the two main ethnic populations

International Journal of Cancer, Volume 158, Issue 6, Page 1528-1540, 15 March 2026.
What's new? Adult T‐cell leukemia/lymphoma (ATL) is a rare and aggressive malignancy caused by human T‐cell leukemia virus type 1 (HTLV‐1). The authors comprehensively analyzed the epidemiological and clinical features of ATL over a 30‐year period in French Guiana, a region with high HTLV‐1 endemicity and a multiethnic population.
Jill‐Léa Ramassamy, Patricia Tortevoye, Balthazar Ntab, Gabriel Carles, Jean‐Pierre Droz, Pierre Couppié, Giovanni Begliomini, Jean‐Francois Carod, N'detodji‐Bill Wankpo, Karim Abdelmoumen, Philippe V. Afonso, Olivier Cassar, Antoine Talarmin, Olivier Hermine, Loïc Epelboin, Ambroise Marçais, Antoine Gessain   +16 more
wiley   +1 more source