Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages. [PDF]
Primary human monocyte-derived macrophages (MDM) were shown to have diminished deoxynucleoside kinase activities compared to T lymphoblasts, and a reduced ability to phosphorylate dideoxynucleosides with anti-human immunodeficiency virus (HIV) activity ...
Carson, DA, Kornbluth, RS, Richman, DD
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Neutrophil‐reactive autoantibodies in blood donors: Can we expect TRALI?
Abstract Background Transfusion‐related acute lung injury (TRALI) is a clinical condition characterized by acute non‐cardiogenic pulmonary edema during or after transfusion. Despite several mitigation strategies, TRALI remains a leading cause of transfusion‐related deaths.
Stefanie Jehle +7 more
wiley +1 more source
Human T-Cell Lymphotropic Virus (HTLV 1/2) in Ecuador: Time for Action
The human T-cell lymphotropic viruses of type 1 and 2 (HTLV 1/2) are retroviruses with estimations of 10 million people infected worldwide. HTLV 1/2 viruses are endemic in South America where Indigenous and Afro American populations are considered of ...
Miguel Angel Garcia-Bereguiain +3 more
doaj +1 more source
Human T-Cell Lymphotropic Virus: A Model of NF-κB-Associated Tumorigenesis
Human T-cell lymphotropic virus type 1 (HTLV-1) is the etiological agent of adult T-cell leukemia/lymphoma (ATL), whereas the highly related HTLV-2 is not associated with ATL or other cancers.
Gutian Xiao, Zhaoxia Qu
doaj +1 more source
High Rate of Human T-Cell Lymphotropic Virus-2 in Patients with HIV in the Peruvian Amazon
HTLV-1/2 in people with HIV (PWH) has been little studied in the Peruvian Amazon, an endemic area for both viruses. We aimed to estimate its prevalence and describe the main clinical and epidemiological features of individuals with HTLV-HIV co-existence.
Silvia Otero-Rodriguez +7 more
doaj +1 more source
Effect of pulsed methylprednisolone on pain, in patients with HTLV-1-associated myelopathy [PDF]
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is an immune mediated myelopathy caused by the human T-lymphotropic virus type 1 (HTLV-1). The efficacy of treatments used for patients with HAM/TSP is uncertain.
Adonis, A +8 more
core +1 more source
A piomiosite tropical (PT) é uma doença infecciosa da musculatura esquelética, de etiologia bacteriana, incomum, e muitas vezes associada a situações de imunodeficiência.
Hérica Cristiani Barra de Souza +5 more
doaj +1 more source
A Fashi Lymphoproliferative Phenotype Reveals Non-Apoptotic Fas Signaling in HTLV-1-Associated Neuroinflammation [PDF]
Human T-cell lymphotropic virus (HTLV)-1 was the first human retrovirus to be associated to cancer, namely adult T-cell leukemia (ATL), but its pathogenesis remains enigmatic, since only a minority of infected individuals develops either ATL or the ...
Anne Mieke Vandamme +18 more
core +1 more source
Post-transcriptional Regulation of HTLV Gene Expression: Rex to the Rescue
Human T-lymphotropic virus type 1 (HTLV-1) and other members of the Deltaretrovirus genus code for a regulatory protein named Rex that binds to the Rex-responsive element present on viral mRNAs.
Donna M. D’Agostino +4 more
doaj +1 more source
Seroprevalence Of Hepatitis-b Virus In Mid And Far Western Region In Nepal [PDF]
Hepatitis B is significant health problems that might involve the late sequel of liver cirrhosis and hepatocellular carcinoma. The present study aimed to know the seroprevalence of hepatitis B virus (HBV) in mid and far western region in Nepal with ...
H, S. A. (Siddiqui) +3 more
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