Results 11 to 20 of about 38,215 (244)

Functional analysis of human T lymphotropic virus type 2 Tax proteins [PDF]

Retrovirology, 2006
Background The Tax proteins encoded by human T lymphotropic virus type 1 (HTLV-1) and type 2 (HTLV-2) are transcriptional activators of both the viral long terminal repeat (LTR) and cellular promoters via the CREB and NFkB pathways. In contrast to HTLV-1,
Gautier Virginie, Lewis Martha, Watters Karen, Lillis Lorraine, Sheehy Noreen, Hall William   +5 more
doaj   +3 more sources

Provirus Mutations of Human T-Lymphotropic Virus 1 and 2 (HTLV-1 and HTLV-2) in HIV-1-Coinfected Individuals

mSphere, 2020
Provirus mutations of human T-lymphotropic virus 1 (HTLV-1), mostly the lack of the 5′ long terminal repeat (LTR) genomic region, have been described and associated with severe adult T cell leukemia/lymphoma (ATLL), non-sense point mutations with low ...
Karoline Rodrigues Campos, Adele Caterino-de-Araujo   +1 more
doaj   +3 more sources

High Rate of Human T-Cell Lymphotropic Virus-2 in Patients with HIV in the Peruvian Amazon [PDF]

Tropical Medicine and Infectious Disease
HTLV-1/2 in people with HIV (PWH) has been little studied in the Peruvian Amazon, an endemic area for both viruses. We aimed to estimate its prevalence and describe the main clinical and epidemiological features of individuals with HTLV-HIV co-existence.
Silvia Otero-Rodriguez, Martin Casapia-Morales, Carmen de Mendoza, Viviana Pinedo-Cancino, Seyer Mego-Campos, Vicente Soriano, Esperanza Merino, José-Manuel Ramos-Rincón   +7 more
doaj   +2 more sources

Human T-lymphotropic virus 2 (HTLV-2) prevalence of blood donors in the state of Pará, Brazil. [PDF]

Braz J Microbiol, 2023
The present study had the objective to describe the molecular prevalence and epidemiological aspects of the human T-lymphotropic virus 2 (HTLV-2) infection in the blood donor population of the Pará state.The present study is a descriptive, retrospective, and cross-sectional review of epidemiological, serological, and molecular data on inapt blood ...
Correa LP, da Costa Farias F, Dos Santos Barile KA, Palmeira MK, de Melo Amaral CE.   +4 more
europepmc   +3 more sources

Clinical Outcome in Human T-Lymphotropic Virus Type 2 Carriers Following Organ Transplantation [PDF]

Transplantation Proceedings, 2020
Frequent and rapid development of myelopathy has been reported in individuals with human T-lymphotropic virus type 1 (HTLV-1) infection following solid organ transplantation. There is no information regarding HTLV-2, a closely related virus that often infects injection drug users.This study includes a retrospective analysis of all consecutive organ ...
Rafael Benito, Joaquina Gil, Juan Sahagún, Vincent Soriano   +3 more
openalex   +6 more sources

Human T lymphotropic virus types 1 and 2: a point of view [PDF]

Revista Brasileira de Hematologia e Hemoterapia, 2013
Reported at the beginning of the 1980s, Human T lymphotropic viruses type 1 and 2 (HTLV1, HTLV 2) were the first retroviruses to have been detected in human beings. HTLV 1 was isolated from adult T-cell leukemia (ATL) and first described by Takatsuki et al. in Japan in 1976, as a malignancy that only affects T cells and only in adults(1, 2).
Angela Cristina Malheiros Luzo
doaj   +3 more sources

Molecular characterization of Human T-cell Lymphotropic Viruses 1 and 2 (HTLV-1 and HTLV-2) in samples from blood donation candidates in the state of Pará, Brazilian Amazon. [PDF]

Braz J Infect Dis
Maneschy CA, Lobo PS, Amaral CEM, Dos Santos Barile KA, de Castro JAA, Silvestre RVD, Freitas FB, Soares LS, Guerra SFS.   +8 more
europepmc   +2 more sources

Development and validation of a multienzyme isothermal rapid amplification and lateral flow dipstick combination assay for HTLV-1 proviral DNA detection [PDF]

Journal of Translational Medicine
Background Human T-cell lymphotropic virus-1(HTLV-1) infection may lead to adult T-cell leukemia, HTLV-associated myelopathy/tropical spastic paraplegia, and various neurological diseases.
Miaomiao Li, Mengjiao Lin, Yushan Xu, Dawei Cui, Jue Xie   +4 more
doaj   +2 more sources

Human T-lymphotropic virus types 1 and 2 are rare among intravenous drug users in Eastern Europe [PDF]

Infection, Genetics and Evolution, 2016
In Europe, human T-lymphotropic virus (HTLV) type 2 mainly occurs among intravenous drug users (IDUs) with prevalence up to 15% and HTLV-1 among general population with prevalence
Ene-Ly Jõgeda, Radko Avi, Merit Pauskar, Eveli Kallas, Tõnis Karki, Don C. Des Jarlais, Anneli Uusküla, Irja Lutsar, Kristi Huik   +8 more
openalex   +3 more sources

Risk factors and epidemiology of human T-lymphotropic virus types 1 and 2 in US blood donors [PDF]

Retrovirology, 2015
Blood donations in the US are routinely screened for markers of human T-lymphotropic virus (HTLV). Seroprevalence and risk factors associated with HTLV-1 and -2 infection from the US Retrovirus Epidemiology Donor Study (REDS-II) Transfusion-Transmitted Viral Infection (TTVI) Rate and Risk Factor Study are reported.
Farnaz Vahidnia, Susan L. Stramer, Debra Kessler, David E. Krysztof, Roger Y. Dodd, E.P. Notari, Simone A. Glynn, Brian Custer   +7 more
openalex   +2 more sources