Results 21 to 30 of about 25,503 (177)

Seroprevalence of HTLV-1/2 among blood donors in the state of Maranhao, Brazil

Revista Brasileira de Hematologia e Hemoterapia, 2014
Background: Infection with human T-lymphotropic virus 1 or 2 (HTLV-1/2) is a major health problem. There is a public health policy defining measures for state hematology and hemotherapy centers in Brazil, in order to avoid virus transmission through ...
Graca Maria de Castro Viana, Maria do Desterro Soares Brandao Nascimento, Rodrigo Artur Souza de Oliveira, Alessandro Carvalho dos Santos, Carolina de Souza Galvao, Marcos Antonio Custodio Neto da Silva   +5 more
doaj   +1 more source

Cellular tropism exhibited by human T lymphotropic virus type 1 (HTLV-1) and type 2 (HTLV-2) [PDF]

Retrovirology, 2011
Background HTLV-1 predominantly transforms CD4+T cells in vitro and induces leukemia and neurological disease in vivo, whereas HTLV-2 shows a preference for CD8+T cell transformation in vitro with limited in vivo pathology. To better understand cellular tropism of HTLV-1 and HTLV-2 early after in vivo infection we determined proviral load and gene ...
Green Patrick L, Doueiri Rami, Yin Han, Kannian Priya   +3 more
doaj   +2 more sources

Short Communication: Current Prevalence and Risk Factors Associated with Human T Lymphotropic Virus Type 1 and Human T Lymphotropic Virus Type 2 Infections Among HIV/AIDS Patients in São Paulo, Brazil [PDF]

AIDS Research and Human Retroviruses, 2015
During the 1990s, high prevalences of HIV/human T lymphotropic virus type 1 (HTLV-1) and HIV/human T lymphotropic virus type 2 ( HTLV-2) coinfections were detected in São Paulo, Brazil in association with intravenous drug use (IDU).
Adele, Caterino-de-Araujo, Cláudio Tavares, Sacchi, Maria Gisele, Gonçalves, Karoline Rodrigues, Campos, Mariana Cavalheiro, Magri, Wong Kuen, Alencar   +5 more
openaire   +2 more sources

Utilization of the CBP but not the p300 co-activator by human T-lymphotropic virus type-2 Tax for p53 inhibition [PDF]

Oncogene, 2004
We previously reported, both in transfected cells and in human T-cell leukemia virus type-2 subtype B infected cells, that the viral transactivator Tax-2B protein could inhibit p53 functions. We have now investigated the mechanism through which Tax-2B represses p53 using GFPTax-2B fusion proteins.
Laurent, Meertens, Cynthia, Pise-Masison, Nelly, Quere, John, Brady, Antoine, Gessain, Renaud, Mahieux   +5 more
openaire   +2 more sources

SHTLV-I/II seroprevalence in blood donors of Hospital Pablo Tobón Uribe Blood Bank during the period 2014-2015

Biomédica: revista del Instituto Nacional de Salud, 2018
Introduction: The human-T cell lymphotropic virus is a retrovirus with various types known so far. HTLV-I and HTLV-II are of clinically importance as they cause different diseases such as adult T-cell leukemia/lymphoma, tropical spastic paraparesis, and ...
Manuela Muñoz, Santiago Carvalho, Jorge Hernando Donado, Gloria Eugenia Barco, Sergio Jaramillo   +4 more
doaj   +1 more source

Human T-lymphotropic virus types 1 and 2 are rare among intravenous drug users in Eastern Europe [PDF]

Infection, Genetics and Evolution, 2016
In Europe, human T-lymphotropic virus (HTLV) type 2 mainly occurs among intravenous drug users (IDUs) with prevalence up to 15% and HTLV-1 among general population with prevalence
Ene-Ly, Jõgeda, Radko, Avi, Merit, Pauskar, Eveli, Kallas, Tõnis, Karki, Don, Des Jarlais, Anneli, Uusküla, Irja, Lutsar, Kristi, Huik   +8 more
openaire   +2 more sources

A Machine Learning Approach for MicroRNA Precursor Prediction in Retro-transcribing Virus Genomes

Journal of Integrative Bioinformatics, 2016
Identification of microRNA (miRNA) precursors has seen increased efforts in recent years. The difficulty in experimental detection of pre-miRNAs increased the usage of computational approaches. Most of these approaches rely on machine learning especially
Demirci Müşerref Duygu Saçar, Toprak Mustafa, Allmer Jens   +2 more
doaj   +1 more source

Prevalence of human T-cell lymphotropic virus types 1 and 2 in blood donors of the Caruaru Blood Center (Hemope)

Revista Brasileira de Hematologia e Hemoterapia, 2013
BACKGROUND: There is difficulty in gathering data on the prevalence of human T-cell lymphotropic virus in blood donors as confirmatory testing is not mandatory in Brazil. This suggests there may be an underreporting of the prevalence.
Waleska Mayara Gomes de Lima, Fabricio Andrade Martins Esteves, Maria do Carmo Morais Rodrigues Torres, Edna Suely Feitosa Pires   +3 more
doaj   +1 more source

Biochemical Characterization, Specificity and Inhibition Studies of HTLV-1, HTLV-2, and HTLV-3 Proteases

Life, 2021
The human T-lymphotropic viruses (HTLVs) are causative agents of severe diseases including adult T-cell leukemia. Similar to human immunodeficiency viruses (HIVs), the viral protease (PR) plays a crucial role in the viral life-cycle via the processing of
Norbert Kassay, János András Mótyán, Krisztina Matúz, Mária Golda, József Tőzsér   +4 more
doaj   +1 more source

Telomere Length, Proviral Load and Neurologic Impairment in HTLV-1 and HTLV-2-Infected Subjects

Viruses, 2016
Short or damaged telomeres have been implicated in degenerative conditions. We hypothesized that analysis of telomere length (TL) in human T-cell lymphotropic virus (HTLV) infection and HTLV-associated neuropathy might provide clues to the etiology of ...
Benjamin Usadi, Roberta Bruhn, Jue Lin, Tzong-Hae Lee, Elizabeth Blackburn, Edward L. Murphy   +5 more
doaj   +1 more source