Functional analysis of human T lymphotropic virus type 2 Tax proteins [PDF]
Background The Tax proteins encoded by human T lymphotropic virus type 1 (HTLV-1) and type 2 (HTLV-2) are transcriptional activators of both the viral long terminal repeat (LTR) and cellular promoters via the CREB and NFkB pathways. In contrast to HTLV-1,
Gautier Virginie +5 more
doaj +3 more sources
Work-Related Human T-lymphotropic Virus 1 and 2 (HTLV-1/2) Infection: A Systematic Review [PDF]
Human T-lymphotropic virus 1 and 2 (HTLV-1/2) belong to the delta group of retroviruses which may cause a life-long infection in humans, HTLV-1 leading to adult T-cell leukemia/lymphoma and other diseases. Different transmission modes have been described,
Angela Stufano +6 more
doaj +4 more sources
Objectives: This study was aimed at determining human T-lymphotropic virus 1/2 prevalence among apparently healthy, immunocompromised and haematologic malignant individuals in Nigeria’s capital, as well as meta-analysis of all Nigerian studies until date.
Nneoma Confidence JeanStephanie Anyanwu +5 more
doaj +3 more sources
Human T-lymphotropic virus 2 (HTLV-2) prevalence of blood donors in the state of Pará, Brazil. [PDF]
The present study had the objective to describe the molecular prevalence and epidemiological aspects of the human T-lymphotropic virus 2 (HTLV-2) infection in the blood donor population of the Pará state.The present study is a descriptive, retrospective, and cross-sectional review of epidemiological, serological, and molecular data on inapt blood ...
Correa LP +4 more
europepmc +3 more sources
Human T lymphotropic virus types 1 and 2: a point of view [PDF]
Reported at the beginning of the 1980s, Human T lymphotropic viruses type 1 and 2 (HTLV1, HTLV 2) were the first retroviruses to have been detected in human beings. HTLV 1 was isolated from adult T-cell leukemia (ATL) and first described by Takatsuki et al. in Japan in 1976, as a malignancy that only affects T cells and only in adults(1, 2).
Angela Cristina Malheiros Luzo
doaj +3 more sources
Clinical Outcome in Human T-Lymphotropic Virus Type 2 Carriers Following Organ Transplantation [PDF]
Frequent and rapid development of myelopathy has been reported in individuals with human T-lymphotropic virus type 1 (HTLV-1) infection following solid organ transplantation. There is no information regarding HTLV-2, a closely related virus that often infects injection drug users.This study includes a retrospective analysis of all consecutive organ ...
Rafael Benito +3 more
openaire +4 more sources
High prevalence of human T-lymphotropic virus 2 (HTLV-2) infection in villages of the Xikrin tribe (Kayapo), Brazilian Amazon region. [PDF]
Studies have shown that the human T-lymphotropic virus 2 (HTLV-2) is endemic in several indigenous populations of the Brazilian Amazon and molecular analyses have shown the exclusive presence of HTLV-2 subtype 2c among the indigenous groups of this geographical region.The present study characterizes the prevalence of HTLV-2 infection in three new ...
Braço ILJ +10 more
europepmc +5 more sources
APOBEC3A, APOBEC3B, and APOBEC3H Haplotype 2 Restrict Human T-Lymphotropic Virus Type 1 [PDF]
ABSTRACT The human APOBEC3 family consists of seven cytidine deaminases (A3A to A3H), some of which display potent antiretroviral activity against HIV-1 and other retroviruses. Studies that analyzed the effect of A3G on human T-lymphotropic virus type 1 (HTLV-1) infectivity resulted in conflicting findings, and our knowledge of ...
Marcel, Ooms +4 more
openaire +2 more sources
Human T-lymphotropic virus type 2 subtype b in a patient with chronic neurological disorder [PDF]
Human T-cell lymphotropic virus is a retrovirus described worldwide. There are four HTLV types: HTLV-1 to 4. Only HTLV-1 and 2 are linked to human disease. The majority of infected individuals remain asymptomatic. However, it is estimated that 5 % of HTLV-1-infected patients present a clinical neurological disorder called HTLV-1-associated myelopathy ...
Carolina, Rosadas +5 more
openaire +2 more sources
Human T Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis in an HIV-Positive Patient Coinfected with Human T Lymphotropic Virus Type 2 Following Initiation of Antiretroviral Therapy [PDF]
We describe a patient coinfected with human immunodeficiency virus (HIV) and human T lymphotropic virus type 2 in Spain who developed paraparesis resembling human T lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis shortly after initiation of highly active antiretroviral therapy, hypothetically as the result of an immune ...
Carlos, Toro +6 more
openaire +2 more sources

