Results 51 to 60 of about 25,503 (177)

Distribution of adult T‐cell leukaemia/lymphoma subtypes and survival outcomes across geographical regions: An international retrospective cohort study

British Journal of Haematology, EarlyView.
Summary Although adult T‐cell leukaemia/lymphoma (ATL) has a higher burden in certain world regions, outcomes have not been directly compared across regions. We conducted a multicentre cohort study comparing the distribution of ATL subtypes and overall survival (OS) across 1090 adults (≥18 years) diagnosed with ATL during 2000–2023 in Japan (n = 366 ...
Bryan Valcarcel, Atae Utsunomiya, Maki Otsuka, Masaharu Miyahara, Kenji Ishitsuka, Yasushi Takamatsu, Junji Suzumiya, Kazuo Tamura, Jule F. Vasquez, Daniel Enriquez‐Vera, Brady E. Beltran, Denisse Castro, Thanya Runciman, Henry Idrobo, Elizabeth Arrieta, Oriana Arias, Eduardo Gotuzzo, Gabriela Garrido‐Pinzás, Victor Rivera, Daniel La Rosa, Camila Peña, Lorena Fiad, Juan C. Ramos, Jose Sandoval‐Sus, Alejandro Sica, Britney N. Bell, Lucy B. Cook, Veronica Leataud, Eliana C. M. Miranda, Carlos Chiattone, Hiroo Katsuya, Luis Malpica   +31 more
wiley   +1 more source

Evaluation of human T-lymphotropic virus prevalence/co-infection rates for a four-year period in a non-metropolitan blood center in Southeast Brazil

Revista da Sociedade Brasileira de Medicina Tropical, 2016
: INTRODUCTION: Human T-lymphotropic virus types 1/2 (HTLV-1/2) are distributed worldwide and are endemic in specific regions. METHODS: Serological evaluation of the HTLV-1/2 prevalence and co-infection rate [human immunodeficiency virus (HIV ...
Mariana Tomazini Pinto, Svetoslav Nanev Slavov, Vanderléia Bárbaro Valente, Eugênia Maria Amorim Ubiali, Dimas Tadeu Covas, Simone Kashima   +5 more
doaj   +1 more source

Triple‐Mutated HSV‐1 Expressing Soluble B7‐1 Plus CTLA‐4 Blockade Suppresses Lymph Node Metastasis in Tongue Cancer

Cancer Science, EarlyView.
In murine tongue cancer models, T‐mB7‐1, a triple‐mutated oncolytic herpes simplex virus type 1 (HSV‐1) engineered to express soluble B7‐1, suppresses cervical lymph node metastasis and improves survival, addressing a major prognostic determinant in oral squamous cell carcinoma (OSCC).
Akinari Sugauchi, Toshihiro Uchihashi, Hirotaka Ito, Miwako Iwai, Yuzuri Tsurumaki Sato, Kyoko Kurioka, Sena Zeynep Usta, Minoru Tanaka, Mikihiko Kogo, Susumu Tanaka, Hiroshi Fukuhara, Tomoki Todo   +11 more
wiley   +1 more source

The efficacy of interactive communication interventions for motivating blood donation: A systematic review

Vox Sanguinis, EarlyView.
Abstract Background and Objectives The global blood product shortage is a persistent problem that urgently needs addressing. Research has investigated the effects of incentives, different interventions and different modes of communication on promoting blood donation; yet, there has been no systematic review comparing interactive communication–based ...
Louisa Boult, Tom Douglass, Madeleine Tremblett, Jack B. Joyce   +3 more
wiley   +1 more source

Spread of Human T-Lymphotropic Virus 1 and 2 Among Relatives of People Who Use Illicit Drugs in Northern Brazil

Frontiers in Microbiology, 2022
The human T-lymphotropic virus 1 (HTLV-1) and 2 (HTLV-2) can be transmitted between humans by mechanisms associated with horizontal and vertical routes. Recently, high prevalence rates and levels of genetic diversity for HTLV-1 and HTLV-2 were detected among people who use illicit drugs (PWUDs) in the Brazilian state of Pará.
Aldemir Branco Oliveira-Filho, Aldemir Branco Oliveira-Filho, Paula Cristina Rodrigues Frade, Ricardo Roberto de Souza Fonseca, Leila Sawada, Luísa Caricio Martins, Luísa Caricio Martins, Luiz Fernando Almeida Machado, Luiz Fernando Almeida Machado, Antonio Carlos Rosário Vallinoto, Antonio Carlos Rosário Vallinoto, Ricardo Ishak, Ricardo Ishak, José Alexandre Rodrigues de Lemos, Benedikt Fischer, Benedikt Fischer, Emil Kupek   +16 more
openaire   +3 more sources

Laboratory Abnormalities in Former Blood Donors Seropositive for Human T-Lymphotropic Virus Types 1 and 2

Archives of Pathology & Laboratory Medicine, 2000
Abstract Context. —The human T-lymphotropic viruses types 1 and 2 (HTLV-1 and HTLV-2) are highly prevalent among injection drug users in the United States.
S A, Glynn, E L, Murphy, D J, Wright, R A, Sacher, J, Fridey, G B, Schreiber   +5 more
openaire   +2 more sources

Rheumatological Manifestations in People Living with Human T-Lymphotropic Viruses 1 and 2 (HTLV-1 and HTLV-2) in Northern Brazil

Viruses
Human T-lymphotropic virus 1 (HTLV-1) infection has been associated with inflammatory, autoimmune, and lymphoproliferative diseases with a wide spectrum of clinical manifestations.
Márcio Yutaka Tsukimata, Bianca Lumi Inomata da Silva, Leonn Mendes Soares Pereira, Bruno José Sarmento Botelho, Luciana Cristina Coelho Santos, Carlos David Araújo Bichara, Gabriel dos Santos Pereira Neto, Aline Cecy Rocha Lima, Francisco Erivan da Cunha Rodrigues, Natália Pinheiro André, Sarah Marques Galdino, Danniele Chagas Monteiro, Ludmila do Carmo de Souza Silva, Lourena Camila Oliveira Araújo, José Ronaldo Matos Carneiro, Rosana de Britto Pereira Cruz, Ricardo Ishak, Antonio Carlos Rosário Vallinoto, Bárbara Nascimento de Carvalho Klemz, Izaura Maria Vieira Cayres Vallinoto   +19 more
doaj   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, Volume 13, Issue 35, 24 June 2026.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Human T-lymphotropic virus 1 and 2 among people who used illicit drugs in the state of Pará, northern Brazil [PDF]

Scientific Reports, 2019
AbstractPeople who used illicit drugs (PWUDs) represent an important population group for acquisition and viral dispersion. In Brazil, high rates of the human T lymphotropic virus 1 (HTLV-1) and 2 (HTLV-2) have been reported in epidemiological studies.
Aldemir B. Oliveira-Filho, Ana Paula S. Araújo, Andreia Polliana C. Souza, Camila M. Gomes, Gláucia C. Silva-Oliveira, Luísa C. Martins, Benedikt Fischer, Luiz Fernando A. Machado, Antonio Carlos R. Vallinoto, Ricardo Ishak, José Alexandre R. Lemos, Emil Kupek   +11 more
openaire   +2 more sources

Discovery of Novel Viruses and Common Contaminants From Unmapped DNA and RNA in Pigs and Chickens Under Different Housing Conditions

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Unmapped sequencing reads in livestock often contain valuable information about pathogens but are typically discarded. We analyzed blood‐derived DNA and RNA from chickens and pigs kept under high‐ and low‐biosecurity conditions, focusing on unmapped reads.
Martijn F. L. Derks, Bert Dibbits, Richard P. M. A. Crooijmans, Kim Lensing   +3 more
wiley   +1 more source