Results 61 to 70 of about 25,647 (176)
A Snapshot of the UK Blood Donor Plasma Virome: A Retrospective Cross‐Sectional Cohort Study
ABSTRACT Estimates of population prevalence and genetic diversity of bloodborne viruses in healthy humans are essential to support population‐scale monitoring for transfusion transmission risk. In the UK and globally, blood donations are routinely screened for a limited number of high‐consequence pathogens, but the full composition of the plasma virome
Kai Kean +12 more
wiley +1 more source
ABSTRACT Directly acting antivirals (DAAs) revolutionised hepatitis C virus (HCV) treatment, offering higher cure rates. We aimed to quantify life expectancy (LE) differences between treated and untreated individuals diagnosed with HCV and assess the contributions of age and causes of death to these differences.
David Etoori +6 more
wiley +1 more source
Inhibition of HIV Type 1 Replication by Human T Lymphotropic Virus Types 1 and 2 Tax Proteins in Vitro [PDF]
Patients with HIV-1 and human T-lymphotropic virus type 2 (HTLV-2) coinfections often exhibit a clinical course similar to that seen in HIV-1-infected individuals who are long-term nonprogressors. These findings have been attributed in part to the ability of HTLV-2 to activate production of antiviral chemokines and to downregulate the CCR5 coreceptor ...
Christy S, Barrios +4 more
openaire +2 more sources
Objectives: To metagenomically analyse blood units originating from the Brazilian Amazon and positive for parenterally transmitted infections (human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), human T-lymphotropic ...
Rafael S. Bezerra +4 more
doaj +1 more source
The susceptibility to Fas-mediated apoptosis was evaluated in seven T-cell lines (two infected with HTLV-2, one with HTLV-1, and four HTLV-free) as well as in Jurkat cells transfected with a Tax-2 expressing vector. Fas-mediated apoptosis was significantly reduced in the HTLV-1- and HTLV-2-infected lines in comparison with the HTLV-free lines ...
G. Zehender +7 more
openaire +4 more sources
Acute encephalopathies in elderly individuals represent a diagnostic challenge, especially when associated with uncommon viral infections such as Human T-cell Lymphotropic Virus Type 1.
Manoella de Miranda da Silva +4 more
doaj +1 more source
Abstract Background and Objectives The global blood product shortage is a persistent problem that urgently needs addressing. Research has investigated the effects of incentives, different interventions and different modes of communication on promoting blood donation; yet, there has been no systematic review comparing interactive communication–based ...
Louisa Boult +3 more
wiley +1 more source
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji +13 more
wiley +1 more source
ORIGIN AND PREVALENCE OF HUMAN T-LYMPHOTROPIC VIRUS TYPE 1 (HTLV-1) AND TYPE 2 (HTLV-2) AMONG INDIGENOUS POPULATIONS IN THE AMERICAS [PDF]
Human T-lymphotropic virus type 1 (HTLV-1) is found in indigenous peoples of the Pacific Islands and the Americas, whereas type 2 (HTLV-2) is widely distributed among the indigenous peoples of the Americas, where it appears to be more prevalent than HTLV-1, and in some tribes of Central Africa.
Paiva, Arthur, Casseb, Jorge
openaire +4 more sources
INTRODUCTION: We investigated the prevalence of human T-cell lymphotropic virus types 1 and 2 (HTLV-1/2) infection in patients with hematological diseases from the western Amazon region of Brazil.
Gemilson Soares Pontes +10 more
doaj +1 more source

