Results 101 to 110 of about 1,288,714 (407)
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2008 Humanity is but a blip on the time-scale of life on earth. But that blip is all that we have, and our present global course guarantees its extinction. What are the realities? Why should the situation be of interest to medical practitioners and what should we be doing?
openaire +4 more sources
FEBS Letters, EarlyView.We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin +2 more
wiley +1 more source
Are We Ready for a True Biopsychosocial–Spiritual Model? The Many Meanings of “Spiritual”
Medicines, 2017 The biopsychosocial model is a modern humanistic and holistic view of the human being in health sciences. Currently, many researchers think the biopsychosocial model should be expanded to include the spiritual dimension as well.
Marcelo Saad +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause +2 more
wiley +1 more source
Book Review: The Age of the Ship of the Line: The British & French Navies, 1650-1815 [PDF]
, 2009 This document is Dr. Oxley\u27s review of The Age of the Ship of the Line: The British & French Navies, 1650-1815 by Jonathan R. Dull. University of Nebraska Press, 2009. 260 pp. Maps, diagrams, notes, index.
Oxley, Robert
core +1 more source
Forum Introduction: Emergent Critical Analytics for Alternative Humanities
Lateral, 2016 Edited by Chris A Eng and Amy K King, this first of a two-part forum identifies and contemplates the emergent potential of four analytics for imagining alternative humanities. Structuring thought across disciplines, these analytics resonate strongly with
Chris A Eng, Amy K King
doaj +1 more source
Art in Occupational Therapy Education: An Exploratory Mixed-Methods Study of an ArtsBased Module
Open Journal of Occupational Therapy, 2017 Art-based learning experiences have demonstrated a range of benefits, including improved observation skills and perspective taking. This article describes the effects of an art-based module in an entry-level curriculum for occupational therapy (OT ...
Susan Coppola +3 more
doaj +1 more source
Immunoregulatory mechanisms of the arachidonic acid pathway in cancer
FEBS Letters, EarlyView.The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine +3 more
wiley +1 more source
Book Reviews: If by Sea: The Forging of the American Navy—From the American Revolution to the War of 1812; The Age of the Ship of the Line: The British & French Navies, 1650-1815; Six Frigates: The Epic History of the Founding of the U.S. Navy [PDF]
, 2010 This document is Dr. Oxley\u27s review of three books: If by Sea: The Forging of the American Navy--From the American Revolution to the War of 1812, by George C. Daughan. Basic Books, 2008. 563 pp. Maps, glossary, notes, bibliography, index.
Oxley, Robert M.
core +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source