Results 111 to 120 of about 957,320 (315)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
, 2014 A couple weeks ago, I closed the stall door behind me in a Patrick Hall bathroom and was greeted by this sign. I quickly scanned the text, smiled at the picture, and had one of those warm, fuzzy, faith-in-humanity-has-been-restored kinds of ...
Davin, Julie E.
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Book review: The politics of humanity: the reality of relief aid [PDF]
, 2013 As UN Under-Secretary-General for Humanitarian Affairs from 2007 until 2010, John Holmes visited some of the most troubled areas of the world and was exposed to the harsh realities of humanitarian aid.
Harmer, Chris
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
On Eternal Punishment: A Brief Dialogue [PDF]
In this brief dialogue I consider the humanity and morality of the doctrine of eternal ...
Oxenberg, Richard
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The contemporary challenges facing college of education students as future educational leaders at Sultan Qaboos University from their view points : Survey study [PDF]
, 2007 The contemporary challenges of young people are matter of high priority, and one of the crucial issues since they are considered as a major part of human capital in Arab States and over the entire world.
Al-Ani, Wajeha Thabit
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FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Preparing a model for measuring satisfaction of electronic services in Mellat Bank [PDF]
مطالعات مدیریت کسب و کار هوشمند, 2015 User satisfaction is a crucial factor for continuous use of e-government services and the success or failure of e-government projects. What are the main challenges for users, which factors measure and influences their satisfaction?
Esmaeel Ahmadi1 +2 more
doaj
Shelter Development Through Cooperatives: A Strategy for Poverty Alleviation and Slum Improvement for Asia and the Pacific Region [PDF]
, 2002 The research traces the flow of humanity from the urban areas to the cities thus creating severe economic and social problems in the cities thus leading to homelessness; lack of sanitation; health hazards; crimes; vandalism; drugs; children wandering ...
M. L. Khurana
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