Results 61 to 70 of about 2,575,597 (213)

Technology and Culture: Humans Inventing Themselves [PDF]

open access: yes, 2013
Since the ancient Greek myth of Prometheus who stole fire from the god, Zeus, humans have been befuddled by their own cleverness. We make useful tools and devices which seem to free humans for higher pursuits only to discover that the unintended ...
Haas, William Paul
core   +1 more source

Explorations in engagement for humans and robots [PDF]

open access: yes, 2005
This paper explores the concept of engagement, the process by which individuals in an interaction start, maintain and end their perceived connection to one another.
Kidd, Cory   +4 more
core   +5 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Humans perceive flicker artifacts at 500 Hz. [PDF]

open access: yes, 2015
Humans perceive a stable average intensity image without flicker artifacts when a television or monitor updates at a sufficiently fast rate. This rate, known as the critical flicker fusion rate, has been studied for both spatially uniform lights, and ...
Davis, James   +2 more
core   +2 more sources

Humans, Humanities, and Humanism in an Age of Technology [PDF]

open access: yes, 2016
Harry Potter’s world as described by J.K. Rowling in a series of books for children is not the world of us, ordinary humans.1 Owls delivering letters overnight would be handy. Howling letters that criticize their recipients in public might be embarrassing.
openaire   +3 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Management of intestinal transplantation in humans [PDF]

open access: yes, 1992
We report here the clinical experience and management guidelines for the nine consecutive cases who received either an isolated small intestinal graft (n = 1) or an intestine liver combination at the University of Pittsburgh, with FK 506 being the basic ...
Abu-Elmagd, K   +14 more
core  

Asymmetry of parietal interhemispheric connections in humans [PDF]

open access: yes, 2011
Visuospatial abilities are preferentially mediated by the right hemisphere. Although this asymmetry of function is thought to be due to an unbalanced interaction between cerebral hemispheres, the underlying neurophysiological substrate is still largely ...
Bonnì, Sonia   +7 more
core   +2 more sources

Human niche, human behaviour, human nature [PDF]

open access: yesInterface Focus, 2017
The concept of a ‘human nature’ or ‘human natures’ retains a central role in theorizing about the human experience. InHomo sapiensit is clear that we have a suite of capacities generated via our evolutionary past, and present, and a flexible capacity to create and sustain particular kinds of cultures and to be shaped by them.
openaire   +3 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

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