Results 91 to 100 of about 15,911 (332)
Erratum: Need for individual-based evaluation to determine the association between humidifier disinfectants and health injuries [PDF]
, 2021 Hyeong–Cheol Kim +4 more
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Case Reports in Infectious Diseases, 2015 Chryseobacterium indologenes is nonmotile, oxidase, and indole positive Gram-negative aerobic bacilli which is widely found in plants, soil, foodstuffs, and water.
Salih Atakan Nemli +2 more
doaj +1 more source
Enhanced Humidification–Dehumidification (HDH) Systems for Sustainable Water Desalination [PDF]
, 2023 Mauro Luberti, Mauro Capocelli
openalex +1 more source
Sustained inflation at birth did not alter lung injury from mechanical ventilation in surfactant-treated fetal lambs. [PDF]
, 2014 BackgroundSustained inflations (SI) are used with the initiation of ventilation at birth to rapidly recruit functional residual capacity and may decrease lung injury and the need for mechanical ventilation in preterm infants.
Hillman, Noah H +4 more
core +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Automatic Quantifications of Dynamics of Genetic Circuits in a Single Cell in Chemostat [PDF]
, 2015 Modular design of genetic circuits requires iterations of experimental and theoretical efforts to make the design process reliable and the resulting behaviors predictable. This technical report demonstrates a fully automatic experiment procedure by using
Del Vecchio, Domitilla, Huang, Hsin-Ho
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source