Results 71 to 80 of about 3,747 (244)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Emission of Insoluble Mineral Particles from Ultrasonic Humidifiers

, 2018
Ultrasonic humidifier use is a potential source of human exposure to inhalable particulates. This paper focused on the behavior of insoluble iron oxides particles, and aluminum oxide particles in ultrasonic humidifiers.
Yao, Wenchuo
core  

Nosocomial legionellosis associated with use of oxygen bubble humidifiers and underwater chest drains

, 1987
In 1 year 12 of 48 patients who developed fatal pneumonia following admission with non-respiratory disorders to the Hospital Molinette, Torino, yielded Legionella pneumophila serogroup 1 from lung at autopsy. Patients were hospitalized on seven different
CARLE, Flavia, Castellani Pastoris M., Passarino G., Marforio P., Moiraghi A., Barral C., Sciacovelli A.   +6 more
core   +1 more source

Effects of the operational conditions on the membrane and electrode properties of a polymer electrolyte fuel cell

Journal of the Brazilian Chemical Society, 2002
The effects of the operational conditions on the membrane and electrode properties on a polymer electrolyte fuel cell (PEFC) were investigated as a function of the cell and the gas humidifiers temperatures, the thickness of the membrane, the impregnation
Passos Raimundo R., Ticianelli Edson A.
doaj  

The effect of cool-mist humidifier on concentration of air pollutants and indoor environmental conditions

Journal of Air Pollution and Health
Introduction: Indoor air pollution poses significant health risks, given the substantial time individuals spend indoors. Cool-mist humidifiers have been proposed as a potential intervention for enhancing indoor air quality by influencing pollutant ...
Maryam Malekbala, Zahra Heydari, Seyde Fateme Mousavi, Zahra Arshian Far, Zeinab Khalilnezhad, Roohollah Rostami   +5 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Dirty humidifiers may cause health problems.

, 1988
"December 1988."Shipping list no.: 89-161-P."CPSC issues alert about care of room humidifiers."Caption title.Mode of access ...
U.S. Consumer Product Safety Commission.
core  

ANALISA PERANGKAT HUMIDIFIER PADA VENTILATOR [PDF]

, 2023
This study aims to analyze humidifiers on ventilators for patients. Can find out the analysis of humidifiers on ventilators, explain, and apply knowledge about analysis of humidifiers on ventilators. In this study, quantitative descriptive research types
Priyulida, Fitria, Abdillah, Khairil, Sihotang, Anggi Tutamana, Ulina, Sri   +3 more
core  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source