Results 61 to 70 of about 30,734 (291)

Unrecognized Bomb Hidden in the Babies' Room: Fatal Pulmonary Damage Related with Use of Biocide in Humidifiers

open access: yesEnvironmental Health and Toxicology, 2012
Korea Centers for Disease Control and Prevention recently suggested that prolonged inhalation of water aerosol containing biocide in humidifiers can bring about rapidly progressive respiratory fibrosis, which killed more than nine people, including four ...
H. Cheong, M. Ha, Jong-Hyeon Lee
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Numerical Analysis of an Air Humidification System Using Computational Fluid Dynamics

open access: yesChemical Engineering Transactions, 2022
Air humidification systems are in demand in many industrial and municipal sectors. Bubble columns are one of the most common forms of laboratory-scale humidifiers.
Mohammadreza Zarrabi   +6 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Five probable factors responsible for the COVID-associated mucormycosis outbreak in India

open access: yesInternational Journal of Infectious Diseases, 2021
The second wave of COVID-19 due to the delta variant (B.1.617.2) led to a rapid rise in total coronavirus and COVID-associated mucormycosis cases reported from India.
Khaiwal Ravindra, Ajit Ahlawat
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Highly Efficient, Flexible, and Recyclable Air Filters Using Polyimide Films with Patterned Thru-Holes Fabricated by Ion Milling

open access: yesApplied Sciences, 2019
We present the first demonstration of the environmental application of a polyimide film (Kapton) with patterned thru-holes as a novel, efficient, flexible, recyclable, and active particulate matter (PM) air filter. The Kapton air filter captures PM using
Sang-Jun Choi   +12 more
doaj   +1 more source

Clinical review: Humidifiers during non-invasive ventilation - key topics and practical implications

open access: yesCritical Care, 2011
Inadequate gas conditioning during non-invasive ventilation (NIV) can impair the anatomy and function of nasal mucosa. The resulting symptoms may have a negative effect on patients' adherence to ventilatory treatment, especially for chronic use.
A. E. Esquinas Rodriguez   +8 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Epidemiologic research on lung damage caused by humidifier disinfectants [PDF]

open access: yesEpidemiology and Health, 2016
In April 2011 a tertiary hospital located in Seoul, Korea reported several cases of severe respiratory distress of unknown origin in young adults.
Moo-Song Lee, Hwa Jung Kim
doaj   +1 more source

Home - About - Disclaimer - Privacy