Results 81 to 90 of about 245,591 (295)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Absolute and differential measurement of water vapor supersaturation using a commercial thin-film sensor [PDF]
, 2000 We describe a technique for measuring the water vapor supersaturation of normal air over a temperature range of ...
Chng, C. K. +2 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Rapid-response humidity sensors based on ultra-thin films stacked with single-layer graphene oxide
Results in ChemistryMonitoring and control of humidity is important for industry, agriculture and human activities. Currently, it is achallengeto develop highly sensitive humidity sensors with both the response time and recovery time less than 1 s.Therefore, it isdifficult ...
Junyi Zhu +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Balloon-Shaped Optical Fiber Humidity Sensor Based on PVA Coating for Respiratory Monitoring
PhotonicsA polyvinyl alcohol (PVA)-coated optical fiber humidity sensor for respiratory monitoring is proposed. The humidity sensor forms a fiber Mach–Zehnder interferometer (MZI) by bending the single-mode fiber (SMF) coated with PVA. The refractive index of PVA
Qingfeng Shi +4 more
doaj +1 more source
Sensors, 2016 Since humidity sensors have been widely used in many sectors, a suitable humidity sensing material with improved sensitivity, faster response and recovery times, better stability and low hysteresis is necessary to be developed.
Ashis Tripathy +5 more
doaj +1 more source
Applied Fiber Optic Measurement for Geohydraulic Engineering [PDF]
, 1997 Engineers have long sought the possibility of measuring parameters such as temperature and pressure continuously in the underground with high precision, high spatial resolution and high band width of parameters. Distributed fibre optic measurement offers
Nishigaki, Makoto, Schreck, Martin
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Development of a Waterproof Crack-Based Stretchable Strain Sensor Based on PDMS Shielding
Sensors, 2018 This paper details the design of a poly(dimethylsiloxane) (PDMS)-shielded waterproof crack-based stretchable strain sensor, in which the electrical characteristics and sensing performance are not influenced by changes in humidity.
Seong Kyung Hong +4 more
doaj +1 more source