Results 231 to 240 of about 228,754 (301)

The microenvironment of ulcerated acral melanoma is characterised by an inflammatory milieu and an enhanced humoral immune response

Vázquez-Cruz ME, Basurto-Lozada P, Molina-Aguilar C, van Haastrecht B, Simonin-Wilmer I, Orozco-Ruiz S, Martinez-Said H, Álvarez-Cano A, García-Ortega DY, Ferreira I, Hidalgo-Miranda A, Hinojosa-Ugarte D, Tavares-de-la-Paz LA, Olguin JE, Salinas I, Rodríguez-Pérez A, Martínez-Gómez JM, van der Zee IT, Grimes DR, Saez-Rodriguez J, de la Cruz HV, Newton-Bishop JA, Bishop DT, Levesque MP, Possik PA, Adams DJ, Robles-Espinoza CD.   +26 more
europepmc   +1 more source

Similarly to BmToll9-1, BmToll9-2 Is a Positive Regulator of the Humoral Immune Response in the Silkworm, Bombyx mori. [PDF]

Insects
Liu J, Chen W, Chen S, Li S, Swevers L.
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes, Florian Buehning, Tobias Lerchner, Julia Vogel, Raluca I. Mincu, Matthias Totzeck, Tienush Rassaf, Lars Michel   +7 more
wiley   +1 more source

Evaluation of humoral immune response and milk antibody transfer in calves and lactating cows vaccinated with inactivated H5 avian influenza vaccine. [PDF]

Sci Rep
Abousenna MS, Shafik NG, Abotaleb MM.
europepmc   +1 more source

Fn14 signalling participates in pristane‐induced murine lupus through exacerbating oxidative stress

British Journal of Pharmacology, EarlyView.
Background and Purpose Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by oxidative stress and immune dysregulation. Fibroblast growth factor‐inducible 14 (Fn14) has been implicated in tissue injury, but its specific role in SLE pathogenesis remains unclear.
Zhu Yan, Rongfang Feng, Mai Luo, Yaqi Wang, Min Gao, Qin Chen, Yufei Zhang, Yale Liu, Yumin Xia   +8 more
wiley   +1 more source

Comparative Study of Vaccine-Induced Humoral Immune Response Against Newcastle Disease Virus and Avian Influenza Virus (H9N2) in Different Bird Species of Mashhad Birds Garden. [PDF]

Vet Med Sci
BehrouziNasab O, Rouygari M, Tabari T.
europepmc   +1 more source

Multivalent antibody‐based conjugates as new tools for tailored modulation of G protein–coupled receptors

British Journal of Pharmacology, EarlyView.
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley   +1 more source

PfSPZ Vaccine induces focused humoral immune response in HIV positive and negative Tanzanian adults. [PDF]

EBioMedicine
Tumbo A, Lorenz FR, Yang ASP, Sefried S, Schindler T, Mpina M, Dangy JP, Milando FA, Rashid MA, Nyaulingo G, Ramadhani K, Jongo S, Felgner PL, Abebe Y, Sim BKL, Church LWP, Richie TL, Billingsley PF, Murshedkar T, Hoffman SL, Abdulla S, Kremsner PG, Mordmüller B, Daubenberger C, Fendel R.   +24 more
europepmc   +1 more source

Refining the treatment of immune checkpoint inhibitor–associated myocarditis: Challenges, innovations and rechallenge considerations

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI)‐associated myocarditis has emerged as a severe and clinically complex immune‐related toxicity that poses significant challenges for therapeutic decision‐making in routine cardio‐oncological care. High‐dose corticosteroids remain the first‐line therapy, yet their timing, dosage and tapering require careful clinical ...
Raluca I. Mincu, Lisa Zimmer, Dimitra Vlachopoulou, Elias Haj‐Yehia, Julia Hoffmann, Lars Michel, Elisabeth Livingstone, Dirk Schadendorf, Alpaslan Tasdogan, Matthias Totzeck, Tienush Rassaf   +10 more
wiley   +1 more source