Results 251 to 260 of about 228,754 (301)
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Activin in Humoral Immune Responses
2011The synthesis and secretion of activin A are stimulated in immune cells, including Th2 cells, B cells, peritoneal macrophages, dendritic cells, and mast cells, in response to their activation. The increased expression of activin A is regulated at the level of transcription.
Kenji, Ogawa, Masayuki, Funaba
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The Humoral Immune Response in Autoimmunity
Dermatologic Clinics, 1993Only within the last 5 years have data on variable region sequences of autoantibodies begun to accumulate. Although it is too early to draw final conclusions, certain principles are beginning to emerge. It is clear that self-recognition by the immune system is normal.
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Imitating the humoral immune response
Current Opinion in Chemical Biology, 2003The immune system makes use of two distinct mechanisms to mount an efficient response against almost every foreign macromolecular substance. First, antibodies with their robust immunoglobulin domain architecture provide a rigid scaffold to support six hypervariable loops, capable of forming highly diverse binding sites.
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Complement and the regulation of humoral immune responses
Immunology Today, 1987The complement component C3 is involved in the successful induction of a normal antibody response, but its mode of action is unclear. From studies with complement deficient guinea pigs Erik Böttger and Dieter-Suermann suggest that failure to stimulate antibody generation is the result of C3 depletion, rather than the suppression of activation by C3 ...
E C, Böttger, D, Bitter-Suerman
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Ontogeny of the Ferret Humoral Immune Response
The Journal of Immunology, 1979Abstract Infant ferrets are born with nearly undetectable immunoglobulin levels, but by 9 days of age the infant ferret serum contains 77, 29, and 13% of adult mean serum levels of IgG, IgA, and IgM. Transmucosal uptake of IgG by the infant ferret occurred for the first 30 days of life.
S C, Suffin +3 more
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Development of the Humoral Immune Response of the Pig
American Journal of Veterinary Research, 1971SUMMARY Pig fetuses were immunologically competent to produce antibodies to sheep red blood cells (srbc) by the 74th day of gestation as determined by the Jerne hemolytic plaque technique. Thereafter, the number of plaque-forming cells (pfc)/107 lymphoid cells increased with age and lymphoid tissue development of the fetuses and newborn pigs.
R D, Schultz, J T, Wang, H W, Dunne
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Humoral immune response in patients with hemophilia
Clinical Immunology and Immunopathology, 1987Hemophiliacs require frequent infusions of allogeneic proteins to control bleeding. Previous reports have demonstrated that thymus-derived lymphocytes (T cells) from hemophiliacs are antigenically primed to the lyophilized antihemophilic factor and that natural killer cells from hemophiliacs demonstrate impaired response to interferon-beta and -gamma ...
D S, Matheson +5 more
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Humoral immune responses in cats with dermatophytosis
American Journal of Veterinary Research, 1993Summary The IgG and IgM classes of antibodies to a watersoluble antigen preparation derived from Microsporum canis were determined by elisa in the sera of 79 cats with dermatophytosis confirmed by results of fungal culture, and of 46 specific-pathogen-free-derived, barrier-maintained cats with no previous exposure to dermatophytes.
A H, Sparkes +2 more
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Assessment of the humoral immune response to cancer
Journal of Proteomics, 2012One of the deadly hallmarks of cancer is its ability to prosper within the constraints of the host immune system. Recent advances in immunoproteomics and high-throughput technologies have lead to profiling of the antibody repertoire in cancer patients.
Mairead Anne, Murphy +2 more
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Novel regulators of the humoral immune response
Immunology Today, 1992Activation of mature B cells to proliferation and terminal differentiation is a multistep process controlled mainly by macrophages and T cells. However, there is growing evidence that B cells and other factors can also regulate the humoral immune response.
F, Uher, E, Rajnavölgyi, A, Erdei
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