Results 71 to 80 of about 228,754 (301)

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

The human immune response to tuberculosis and its treatment: a view from the blood. [PDF]

, 2015
The immune response upon infection with the pathogen Mycobacterium tuberculosis is poorly understood, hampering the discovery of new treatments and the improvements in diagnosis.
van Helden, Paul, van Helden, P., Cliff, Jacqueline M, Kaufmann, Stefan HE, O'Garra, Anne, Kaufmann, S., McShane, H., O'Garra, A., Cliff, J., McShane, Helen   +9 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Immune challenge mediates vocal communication in a passerine bird: an experiment

, 2004
Secondary sexual characters may have evolved in part to signal resistance to parasites. Avian song has been hypothesized to be involved in this process, but the role of parasites in modulating acoustic communication systems in birds remains largely ...
Michl, Gábor, Anders Pape Møller, Richard, Murielle, Gábor Michl, Török, János, János Török, László Zsolt Garamszegi, Moller, Anders Pape, Péczely, Péter, Péter Péczely, Murielle Richard, Garamszegi, L\ue1szl\uf3, Garamszegi, László Zsolt   +12 more
core   +1 more source

Saccharomyces uvarum mannoproteins stimulate a humoral immune response in mice [PDF]

, 2012
Yeasts discarded in industrial processes can be used as a nutritional supplement and to extract cellular components with biotechnological aims. In this study, the humoral immune response of Swiss mice treated with mannoproteins (MP) from the yeast ...
Castro-Goméz,Raul Jorge Hernan, Raul Jorge Hernan Castro-Goméz, Eto,Silas Fernandes, Silas Fernandes Eto, Venancio,Emerson José, Darpossolo,Fernanda Patrícia Brito, Emerson José Venancio, Fernanda Patrícia Brito Darpossolo   +7 more
core   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Humoral and cellular immune response to second and third severe acute respiratory syndrome coronavirus 2 mRNA vaccine in patients with plasma cell dyscrasia

Cancer Medicine, 2023
Background The recently developed severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) mRNA vaccine has a short history of use and further information is needed regarding its efficacy, especially in immunocompromised conditions, such as plasma ...
Tomotaka Suzuki, Shigeru Kusumoto, Yoshiko Kamezaki, Hiroya Hashimoto, Nozomi Nishitarumizu, Yoko Nakanishi, Yukiyasu Kato, Akimi Kawai, Naohiro Matsunaga, Toru Ebina, Tomoyuki Nakamura, Yoshiaki Marumo, Kana Oiwa, Shiori Kinoshita, Tomoko Narita, Asahi Ito, Atsushi Inagaki, Masaki Ri, Hirokazu Komatsu, Takashi Aritsu, Shinsuke Iida   +20 more
doaj   +1 more source

Humoral immune response against inactivated EV71 vaccine in monkeys.

, 2018
Humoral immune response against inactivated EV71 vaccine in monkeys.
Young Ki Choi (338498), Yeung Bae Jin (388044), Sang-Won Lee (193873), Hyun Ju In (4045451), Kang-Jin Jeong (282190), Jung Sik Yoo (4045445), Heeji Lim (4045454), Jung-Ah Lee (4045448), June-Woo Lee (323694), Sang-Rae Lee (282186), Ji-Yeon Hyeon (4045442)   +10 more
core   +1 more source

Lactation is Associated with Accelerated Postpartum Pelvic Floor Muscle Recovery in a Pregnant Simulated Birth Injury Model

Advanced Science, EarlyView.
ABSTRACT Healthy pelvic floor muscles (PFMs) are essential for proper pelvic floor function. The biggest risk factor for PFM dysfunction is injury sustained during vaginal childbirth, yet the factors that facilitate or impair PFM recovery from birth injury remain unknown.
Bianca L. Peña, Khushi M. Diwakar, Hillary K. Tran, Selena Cao, Celeste E. Lintz, Laila N. Hayes, Marianna Alperin, Karen L. Christman   +7 more
wiley   +1 more source

Reprogramming Antitumor Immunity: NK Cell Strategies to Navigate the Immunosuppressive Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumor immune escape is a major barrier to durable cancer immunotherapy, as advanced malignancies create a tumor microenvironment (TME) that preferentially exhausts and disables T cell responses. While most approved cell therapies are T cell‐based, this limitation motivates the exploration of an alternative effector cell platform.
Tereza Kochs, Pranay Nath, Alice Chen, Rizwan Romee, Andreia Maia   +4 more
wiley   +1 more source