Results 181 to 190 of about 173,621 (252)

IL-6-induced C/EBPα drives follicular regulatory T cell differentiation to regulate humoral immunity in mice. [PDF]

Nat Commun
Lee H, Kim CJ, Ahn H, Cho G, Mun SH, Kim SW, Choi HS, Um D, Kim H, Ko H, Noh J, Park JC, Park HE, Sharma A, Lee Y, Lee SW, Choi YS, Suh CH, Kim JW, Kim TK, Hwang CS, Kim JK, Kim S, Im SH.   +23 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

PTEN-mTORC2 signaling module controls antibody isotype selection and antiviral humoral immunity. [PDF]

Front Immunol
Thapa B, Lee Y, Pak S, Kim D, Kwon HJ, Lee K.   +5 more
europepmc   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes, Florian Buehning, Tobias Lerchner, Julia Vogel, Raluca I. Mincu, Matthias Totzeck, Tienush Rassaf, Lars Michel   +7 more
wiley   +1 more source

Dietary supplementation of arachidonic acid promotes humoral immunity. [PDF]

EMBO Mol Med
Feng S, Ma E, Na X, Wang Z, Tai W, Bao X, Wang M, Chang H, Wu B, Liu M, Li J, Shi H, Yang C, Xi M, Yang H, Li Y, Zhu Y, Wang P, Zhao L, Zhao A, Cheng G.   +20 more
europepmc   +1 more source

Refining the treatment of immune checkpoint inhibitor–associated myocarditis: Challenges, innovations and rechallenge considerations

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI)‐associated myocarditis has emerged as a severe and clinically complex immune‐related toxicity that poses significant challenges for therapeutic decision‐making in routine cardio‐oncological care. High‐dose corticosteroids remain the first‐line therapy, yet their timing, dosage and tapering require careful clinical ...
Raluca I. Mincu, Lisa Zimmer, Dimitra Vlachopoulou, Elias Haj‐Yehia, Julia Hoffmann, Lars Michel, Elisabeth Livingstone, Dirk Schadendorf, Alpaslan Tasdogan, Matthias Totzeck, Tienush Rassaf   +10 more
wiley   +1 more source

Humoral immunity and infection status of PLWH following vaccination after the BA.5/BF.7 wave. [PDF]

Front Microbiol
Xie Y, Song X, Yang L, Wang L, Gao H, Zhang L, Feng Y, Chen Y, Yan H, Feng F, Dai E, Wang Y, Feng A.   +12 more
europepmc   +1 more source

The ongoing oleoylethanolamide story: Therapeutic implications in the control of obesity and its comorbidities

British Journal of Pharmacology, EarlyView.
The global burden of obesity continues to rise, demanding effective pharmacological strategies for individuals in whom prevention alone is insufficient. Recent incretin‐based and multi‐agonist therapies have delivered unprecedented weight loss, demonstrating that the simultaneous modulation of multiple metabolic pathways can optimize body weight ...
Marzia Friuli, Alessia Campagna, Barbara Eramo, Christian Sepe, Annarita Zuena, Silvana Gaetani, Adele Romano   +6 more
wiley   +1 more source

Immunoglobulin allotypes and <i>RELN</i> alleles and humoral immunity to HSV1 in patients with Alzheimer's disease and matched controls. [PDF]

J Alzheimers Dis
Pandey JP, Namboodiri AM, Nietert PJ.
europepmc   +1 more source