Results 191 to 200 of about 173,621 (252)

Investigation of the mechanisms and modulation of irinotecan‐induced emesis in Suncus murinus

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Irinotecan is a widely used chemotherapeutic agent that frequently causes nausea and emesis. Its emetic mechanism of action is poorly understood and the choice of drugs to reduce nausea and emesis is largely empirical. Experimental Approach Using Suncus murinus, we examined (i) the dose–response and temporal profile of ...
Zengbing Lu, Julia Y. H. Liu, Yasuhiro Nakagami, Zitong Li, Xiaofei Huang, Man P. Ngan, Dexuan Cui, John A. Rudd   +7 more
wiley   +1 more source

A p53 peptide mucosal vaccine induces cellular and humoral immunity and anti-tumor effects in a murine colorectal cancer model. [PDF]

Cancer Gene Ther
Wang SH, Cao Z, Janczak KW, Feng Y, Green M, Tang S, Fearon ER, Baker JR.   +7 more
europepmc   +1 more source

The fight of innate immunity and abnormal cannabinoids against Candida infection

British Journal of Pharmacology, EarlyView.
Candida species represent the most clinically significant fungal pathogens in humans, with invasive candidiasis carrying a mortality of 30%–40% in critically ill patients despite modern antifungal therapy. The innate immune system – through the coordinated and specific activities of neutrophils, macrophages, NK cells, mast cells and eosinophils ...
Prince Ofori, Ilan Zaffran, Francesca Levi Schaffer   +2 more
wiley   +1 more source

Mpox-specific cellular and humoral immunity in mpox survivors living with HIV. [PDF]

Cell Rep
Stampfer SD, Priyamvada L, Sambyal S, Gangadhara S, Moriarty M, Satheshkumar PS, Grifoni A, Sette A, Sheth AN, Kelley CF, Amara RR.   +10 more
europepmc   +1 more source

Dissecting infant and maternal antibody repertoires exposes the early onset of infant humoral immunity. [PDF]

Clin Transl Immunology
Bondt A, Tan M, Dingess KA, van Rijswijck DM, Chen Y, Zhu S, Tian Y, Lin T, Zhang Y, Huang Y, Wang G, Zhu J, Guo J, Heck AJ.   +13 more
europepmc   +1 more source

Peanut‐Specific IgG4 mAbs Promote Regulatory Immune Responses Ex Vivo and Improve Oral Immunotherapy in Mice

Clinical &Experimental Allergy, EarlyView.
Allergen‐specific IgG4 mAbs were shown to block facilitated IgE binding to B cells and redirect allergens towards myeloid APC, leading to increased IL‐10 production in vitro. In combination with oral AIT, the mAbs inhibited mast cell activation and sustained allergen‐specific IgG4 levels in an in vivo model of peanut allergy. ABSTRACT Background Peanut
Pascal Gasser, Alex A. J. Overman, Mojtaba Porbahaie, Chiara Arena, Juliane Konrad, Renate Repke, Sandra Götschi, Dimitri Bieli, Tiziana Sonati, Alcide Barberis, Niccolò Pengo, R. J. Joost van Neerven, Natascha Wuillemin   +12 more
wiley   +1 more source

Tertiary Lymphoid Organs at the Center Stage of Skin's Humoral Immunity. [PDF]

Immunol Rev
Gribonika I.
europepmc   +1 more source

Influence of B cell-lineage targeted CAR-T cell therapy on humoral immunity and vaccine-induced antibody response. [PDF]

Nat Commun
Ozog S, Krantz EM, Tindbaek K, Munoz J, Liu WL, Chalal C, Pernikoff S, Yahya K, Stevens-Ayers T, Dasgupta S, Cowan AJ, Green DJ, Gauthier J, Till BG, Gardner RA, Shadman M, Bleakley M, Boeckh M, Boonyaratanakornkit J, Turtle CJ, Hill JA.   +20 more
europepmc   +1 more source

Synbiotic supplementation modulates humoral immunity and cecal microbiota in broiler chickens exposed to subclinical doses of fumonisins and deoxynivalenol. [PDF]

Front Physiol
Dasireddy JR, Kappari L, Selvaraj RK, Applegate TJ, Shanmugasundaram R.   +4 more
europepmc   +1 more source

A Fiber- and Polyphenol-Enriched Diet Enhances Humoral Immunity, Reshapes Cecal Microbiota, and Improves Short-Chain Fatty Acid Production in Female Wistar Rats. [PDF]

Nutrients
Casanova-Crespo S, Ceballos-Sánchez D, Vallverdú-Queralt A, Rodríguez-Lagunas MJ, Massot-Cladera M, Castell M, Pérez-Cano FJ.   +6 more
europepmc   +1 more source