Results 51 to 60 of about 99 (99)
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT The unprecedented effort to cope with the COVID‐19 pandemic has unlocked the potential of mRNA vaccines as a powerful technology, set to become increasingly pervasive in the years to come. As in other areas of drug development, mathematical modeling is a pivotal tool to support and expedite the mRNA vaccine development process.
Lorenzo Dasti +8 more
wiley +1 more source
Malignancies and immunoglobulin G4‐related disease
Rheumatology &Autoimmunity, EarlyView.Immunoglobulin G4‐related disease (IgG4‐RD) is associated with increased cancer risk. Malignancies affect both IgG4‐RD involved organs, such as the lung, pancreas, bile duct, and prostate, and noninvolved organs, such as the gastrointestinal duct. B‐cell neoplasms constitute a proportion of the malignancies linked to this disease.
Jingna Li, Wen Zhang
wiley +1 more source
Potential roles of antibodies with different classes in IgG4‐related diseases
Rheumatology &Autoimmunity, EarlyView.This review discussed the common characteristics of different classes of antibodies and their potential corresponding unique mechanisms involved in immunoglobulin G4‐related disease. Abstract Immunoglobulin G4‐related disease (IgG4‐RD), first identified two decades ago, is an immune‐mediated pro‐inflammatory and profibrotic disease entity affecting ...
Ling Li +6 more
wiley +1 more source
Small, EarlyView.This review explores the potential of antimicrobial peptides (AMPs) and nanotechnology for the treatment of gastrointestinal infections. It analyzes bacterial resistance mechanisms, the antimicrobial actions of AMPs, and advances in nanocarriers, such as lipid‐based, polymeric, metallic, and mesoporous silica systems, that enhance peptide protection ...
Christian Shleider Carnero Canales +10 more
wiley +1 more source
Microneedle delivery systems for vaccines and immunotherapy
Smart Molecules, EarlyView.This paper reviews the preparation methods and materials of microneedles for drug delivery, summarizes the structures and types of microneedle systems, analyzes the influence of antigens and adjuvants on the efficacy of microneedle vaccines, and reviews the current application status of microneedles in the fields of vaccines and immunotherapy by ...
Haiyao Jia +5 more
wiley +1 more source
Small Science, EarlyView.Poly (lactic‐co‐glycolic acid) is used to prepare nonspherical particles—macrofibers, macrothreads, and nanothreads (PNTs)—via one‐step solvent phase separation. PNT‐stabilized Pickering emulsions exhibit superior humoral and cellular immune enhancement over spherical particles and emulsions, highlighting the potential of nonspherical particles and ...
Yanan Li +6 more
wiley +1 more source
Small Science, EarlyView.Both native and engineered extracellular vesicles (EVs) are served as promising therapeutic agents for treating acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). To circumvent the limitations of native EVs, various engineering strategies are adopted.
Zhengyan Gu +12 more
wiley +1 more source
Small Structures, EarlyView.This illustration depicts a comprehensive strategy against monkeypox, showcasing its transmission, symptoms, and prevention. Centralized around nanomaterials and biosensors, it integrates early screening, Internet of Things, vaccination, and community involvement through collaboration among healthcare workers, scientists, researchers, social groups ...
Vishal Chaudhary +3 more
wiley +1 more source
The Chemical Record, EarlyView.The radical Pietist Johann Conrad Dippel was a self‐proclaimed adept – a maker of gold and the philosophers’ stone. He was also a magister of theology, a doctor of medicine, and a self‐taught chemist, who coinvented the pigment Prussian Blue together with Johann von Diesbach, became known for his animal pyrolysis oil, his wonder‐wound balm, his ...
Curt Wentrup
wiley +1 more source
The regulatory effects and applications of TIGIT/CD155 on the tumor microenvironment in HCC
VIEW, EarlyView.Background The interaction between TIGIT and CD155 compromises immune cell efficacy in tumor targeting, potentially driving hepatocellular carcinoma (HCC) progression through diverse molecular pathways. What Was Done This study investigates the interplay between CD155 and TIGIT in regulating CD8+ T cell function and elucidates its implications in HCC ...
Wenting Li +10 more
wiley +1 more source