Results 161 to 170 of about 36,080 (282)

Co-Design of a New Integrated Care Model With People Affected by Huntington's Disease: A Mixed Methods Study. [PDF]

Health Expect
Pires SB, Kunkel D, Manera K, Goodwin N, Kipps C, Portillo MC.   +5 more
europepmc   +1 more source

Decreased Striatal RGS2 Expression Is Neuroprotective in Huntington's Disease (HD) and Exemplifies a Compensatory Aspect of HD-Induced Gene Regulation

, 2011
Tamara Seredenina, Özgün Gökçe, Ruth Luthi‐Carter   +2 more
openalex   +2 more sources

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

“Ectopic” theta oscillations and interictal activity during slow-wave state in the R6/1 mouse model of Huntington's disease

, 2012
Michele Pignatelli, Fanny Lebreton, Yoon H. Cho, Xavier Leinekugel   +3 more
openalex   +2 more sources

Multiple Sources of Striatal Inhibition Are Differentially Affected in Huntington's Disease Mouse Models [PDF]

, 2013
Carlos Cepeda, Laurie Galvan, Sandra M. Holley, Shilpa P. Rao, Véronique André, Elian P. Botelho, Jane Chen, Joseph B. Watson, Karl Deisseroth, Michael S. Levine   +9 more
openalex   +1 more source

Transcriptional regulation of human NMNAT2: insights from 3D genome sequencing and bioinformatics

The FEBS Journal, EarlyView.
NMNAT2 is a valuable drug target, as low levels increase the risk of neurodegeneration. We employed 4C‐seq to identify NMNAT2 regulatory regions in the human genome, revealing distinct interactomes of the NMNAT2 promoter in undifferentiated and neuron‐like SH‐SY5Y cells. Additionally, we uncovered NMNAT2‐associated genes and transcription factors. This
Yu Chen Chang, Sen Yang, Minyoung Cho, Kwangsik Nho, José‐Manuel Baizabal, Hui‐Chen Lu   +5 more
wiley   +1 more source

Huntington's Disease (HD): Neurodegeneration of Brodmann's Primary Visual Area 17 (BA17)

, 2014
Udo Rüb, Kay Seidel, Jean Paul Vonsattel, Herwig W. Lange, Wolfgang Eisenmenger, M. Götz, Domenico Del Turco, Mohamed Bouzrou, Horst‐Werner Korf, Helmut Heinsen   +9 more
openalex   +2 more sources

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

The role of oligodendroglial dysfunction in Huntington's disease. [PDF]

J Huntingtons Dis
Li X, Li S, Li XJ, Nguyen HP, Petersen A, Pouladi MA.   +5 more
europepmc   +1 more source

Huntington's disease associations in Australia [PDF]

, 1990
Robyn Kapp
openalex   +1 more source