Results 171 to 180 of about 37,609 (272)

Technologies for engineering repetitive DNA

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long‐read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth.
Shuting Ma, Yali Cui, Yi Wu
wiley   +1 more source

Inhibition of the NLRP3 Inflammasome With MCC950 Improves Gut Health in Huntington's Disease Mice. [PDF]

J Neurochem
Sarkar SK, Ekwudo MN, Lu D, Masson B, Kiridena P, van de Garde N, Renoir T, Vince JE, Deepagan VG, Hannan AJ, Gubert C.   +10 more
europepmc   +1 more source

A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies

Traffic, Volume 27, Issue 3, September 2026.
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby, Gunjan Misri, Naava Naslavsky, Steve Caplan   +3 more
wiley   +1 more source

Exploring huntington's disease from a neurodevelopmental perspective. [PDF]

Int J Biol Sci
Huang C, Zheng X, Li W, Zhang Z, Li S, Li XJ, Rong M, Yan S.   +7 more
europepmc   +1 more source

Imaging Venous Transit Time and Blood–Brain Barrier Permeability of the Deep Brain

Magnetic Resonance in Medicine, Volume 96, Issue 2, Page 809-816, August 2026.
ABSTRACT Purpose Imaging of venous vessels with advanced pulse sequences allows the assessment of important hemodynamic parameters. Previous work has measured venous transit time (VTT) and blood–brain barrier (BBB) water permeability in cortical tissue.
Wen Shi, Jie Song, Jiani Wu, Yifan Gou, Zhiyi Hu, Vivek Yedavalli, Zixuan Lin, Hanzhang Lu   +7 more
wiley   +1 more source

Pain processing and pain assessment in Huntington's disease: Study protocol of the Huntington's disease - PAIN study. [PDF]

PLoS One
Sprenger GP, van Velzen M, Achterberg WP, Roos RAC, de Bot ST.   +4 more
europepmc   +1 more source

Advancing Quantitative Susceptibility Mapping With 2.5D Diffusion Models for Rapid Intracranial Hemorrhage Quantification

Magnetic Resonance in Medicine, Volume 96, Issue 2, Page 596-610, August 2026.
ABSTRACT Purpose To develop a generative diffusion model‐based approach for robust and efficient quantitative susceptibility mapping (QSM) reconstruction in intracranial hemorrhage (ICH), applicable to both standard gradient echo (GRE) and rapid echo planar imaging (EPI) acquisitions.
Zhuang Xiong, Yang Gao, Feng Liu, Derek Emery, Ken Butcher, Alan H. Wilman, Hongfu Sun   +6 more
wiley   +1 more source

Novel Compounds for Treating Huntington's Disease. [PDF]

ACS Med Chem Lett
Sabnis RW, Sabnis AR.
europepmc   +1 more source

GIP in Cardiovascular and Kidney Disease: From Physiology to Pharmacology

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6509-6532, August 2026.
ABSTRACT Aims To provide a comprehensive overview of the cardiovascular and renal effects of glucose‐dependent insulinotropic polypeptide (GIP) by integrating its physiological role with recent human trial data on tirzepatide, the first dual GIP and glucagon‐like peptide‐1 (GLP‐1) receptor agonist.
Michelantonio De Fano, Line L. Haurum, Christine R. Schwarz, Francesca Porcellati, Andreas Andersen   +4 more
wiley   +1 more source

Huntington's disease clinical trials update: October 2025. [PDF]

J Huntingtons Dis
Farag M, Tabrizi SJ, Wild EJ.
europepmc   +1 more source