Results 251 to 260 of about 93,886 (309)
Author Correction: Neuroprotective role of Sirt1 in mammalian models of Huntington’s disease through activation of multiple Sirt1 targets [PDF]
Mali Jiang, Jiawei Wang, Jinrong Fu, Lin Du, Hyunkyung Jeong, Tim West, Lan Xiang, Peng Qi, Zhipeng Hou, Huan Cai, Tamara Seredenina, Nicolas Arbez, Shanshan Zhu, Katherine Sommers, Jennifer Qian, Jiangyang Zhang, Susumu Mori, X. William Yang, Kellie L. Tamashiro, Susan Aja, Timothy H. Moran, Ruth Luthi‐Carter, Bronwen Martin, Stuart Maudsley, Mark P. Mattson, Robert H. Cichewicz, Christopher A. Ross, David M. Holtzman, Dimitri Krainc, Wenzhen Duan +29 moreopenalex +1 more sourceFunctional Training Mitigates Reduced Circulating Indole‐3‐Lactate Levels in Persons With Relapsing–Remitting Multiple Sclerosis
Acta Physiologica, Volume 242, Issue 3, March 2026.ABSTRACT Aim
Indoles are tryptophan (Trp)‐derived metabolites that are produced by the gut microbiota and may influence the gut‐microbiota‐brain axis in multiple sclerosis (MS). Indole‐3‐lactate (ILA) is reduced in persons with MS and improves MS clinical scores in animal models via its anti‐inflammatory remyelinating properties.Tiffany Wences Chirino, Frederike Adammek, Sergen Belen, Matteo Winker, Sebastian Proschinger, Annette Rademacher, Marit L. Schlagheck, Alexander Schenk, Marie Kupjetz, David Walzik, Clemens Warnke, Marcel Reuter, Friederike Rosenberger, Tim Meyer, Adrian McCann, Per Magne Ueland, Niklas Joisten, Philipp Zimmer +17 morewiley +1 more sourceAdditional file 2 of Pathobiology of the autophagy-lysosomal pathway in the Huntington’s disease brain
Berg, Martin J., Veeranna, Rosa, Corrinne M., Kumar, Asok, Mohan, Panaiyur S., Stavrides, Philip, Darji, Sandipkumar, Marchionini, Deanna M., Yang, Dun-Sheng, Nixon, Ralph A. +9 moreopenalex +1 more sourceVisuospatial Processing Deficits Linked to Posterior Brain Regions in Premanifest and Early Stage Huntington’s Disease
, 2016 Izelle Labuschagne, Amy Mulick, Rachael I. Scahill, Eileanoir B. Johnson, Elin M. Rees, Alison O’Regan, Sarah Queller, Chris Frost, Blair R. Leavitt, Alexandra Dürr, Raymond A.C. Roos, Gail Owen, Beth Borowsky, Sarah J. Tabrizi, Julie C. Stout, the TRACK-HD Investigators +15 moreopenalex +2 more sourcesSialylation patterns in cerebral amyloid angiopathy
Brain Pathology, Volume 36, Issue 2, March 2026.This study is the first to localize and evaluate sialylation modifications in the context of Alzheimer's Disease and Cerebral Amyloid Angiopathy, revealing a unique disease‐specific increase in intravascular sialylation. Abstract
Glycosylation is the most common form of post‐translational modification in the brain and becomes significantly altered in ...Caitlyn Fastenau, Rebecca Crisp, Mallory Keating, Elizabeth Ochoa, Timothy E. Richardson, Margaret E. Flanagan, Jamie M. Walker, Sarah C. Hopp, Kevin F. Bieniek +8 morewiley +1 more sourceLowering the HTT1a transcript as an effective therapy for Huntington’s disease
Papadopoulou AS, Alterman J, Landles C, Smith EJ, Conroy F, Phillips J, Canibano-Pico M, Nita IM, Osborne GF, Iqbal A, Aldous SG, Bondulich MK, Gomez-Paredes C, Sathasivam K, O’Reilly D, Echeverria D, Bobkov K, Greene JR, Aronin N, Khvorova A, Bates GP. +20 moreeuropepmc +1 more source