Results 261 to 270 of about 10,552,439 (323)

From genes to trajectories: mapping genetic influences on Huntington's disease progression. [PDF]

Bioinformatics
Dey S, Sun Z, Warner J, Koski E, Eyigoz E, Sathe S, Sampaio C, Hu J.   +7 more
europepmc   +1 more source

Huntingtin in the amygdaloid basolateral complex is correlated with Vonsattel staging in Huntington's disease. [PDF]

Brain Commun
Sanchez-Migallon P, Flores-Cuadrado A, Villanueva-Anguita P, Rabano A, Vaamonde J, Saiz-Sanchez D, Mohedano-Moriano A, Astillero-Lopez V, Soriano-Herrador C, Martinez-Marcos A, Ubeda-Banon I.   +10 more
europepmc   +1 more source

Branched‐Chain Amino and Keto Acids Reduce Hepatocyte Lipid Droplet Size and Number via Distinct Proteomic Pathways

PROTEOMICS, Volume 26, Issue 7, Page 146-157, July 2026.
ABSTRACT Branched‐chain amino acids (BCAA) and their corresponding keto acids (BCKA) have been associated with changes in hepatic lipid metabolism and the resulting alterations in intracellular triglyceride concentrations. In this study, we utilized a previously established hepatocyte model to investigate the impact of BCAA and BCKA supplementation on ...
Jayasimha R. Daddam, Mounica Sura, Edward Kolodziej, Maria Gojcaj, Zheng Zhou   +4 more
wiley   +1 more source

Lowering the HTT1a transcript as an effective therapy for Huntington’s disease

Papadopoulou AS, Alterman J, Landles C, Smith EJ, Conroy F, Phillips J, Canibano-Pico M, Nita IM, Osborne GF, Iqbal A, Aldous SG, Bondulich MK, Gomez-Paredes C, Sathasivam K, O’Reilly D, Echeverria D, Bobkov K, Greene JR, Aronin N, Khvorova A, Bates GP.   +20 more
europepmc   +1 more source

Oxidative Stress in Huntington's Disease. [PDF]

Biomolecules
Jiménez-Jiménez FJ, Alonso-Navarro H, García-Martín E, Cárcamo-Fonfría A, Caballero-Muñoz MDM, Agúndez JAG.   +5 more
europepmc   +1 more source

The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum)

Phytotherapy Research, Volume 40, Issue 7, Page 4588-4610, July 2026.
The Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Jessica Maiuolo, Valeria Mazza, Rosamaria Caminiti, Francesca Oppedisano, Saverio Nucera, Salvatore Ragusa, Sara Ilari, Lucia Carmela Passacatini, Luigi Tucci, Giuseppe Trunfio, Vincenzo Mollace, Carolina Muscoli   +11 more
wiley   +1 more source

Goal-directedness deficit in Huntington's disease. [PDF]

Cogn Affect Behav Neurosci
Morris LA, Manohar S, Horne KL, Paermentier L, Buchanan CM, MacAskill MJ, Myall DJ, Husain M, Roxburgh R, Anderson TJ, Le Heron CJ.   +10 more
europepmc   +1 more source

Gastroscopic Evaluation of Gastric Mucosa in Horses Treated With Flunixin Meglumine or High‐Dose Firocoxib: A Descriptive Pilot Study

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
In this descriptive pilot study, short‐term (5‐day) high‐dose firocoxib (1.0 mg/kg) was not associated with detectable gastric mucosal injury in horses. Due to non‐randomised design and small sample size (n = 5/group), no causal conclusions can be drawn. Findings are hypothesis‐generating and require confirmation in adequately powered trials.
Renato Abrantes de Oliveira, Alexandre da Silva Correa, Francisco Décio de Oliveira Monteiro, Pedro Paulo Maia Teixeira   +3 more
wiley   +1 more source

Large scale functional and effective connectivity alterations cross the Huntington's disease integrated staging system. [PDF]

Neuroimage Clin
Demirtas M, Pustina D, Wood A, Sampaio C, Vohryzek J, Deco G.   +5 more
europepmc   +1 more source