Results 271 to 280 of about 93,886 (309)

Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling

Brain and Behavior, Volume 16, Issue 2, February 2026.
Histone methylation and acetylation modulate gene expression by inducing chromatin condensation or relaxation, which in turn regulates transcriptional activity and impacts neurogenesis. ABSTRACT Aims The purpose of this review is to examine how epigenetic regulation particularly chromatin modification and histone methylation controls gene expression ...
Degisew Yinur Mengistu, Biniam Moges Eskeziyaw   +1 more
wiley   +1 more source

A digital motor score for sensitive detection of progression in Huntington's disease. [PDF]

Brain
Giboin LS, Simillion C, Rennig J, Bamdadian A, Kinsella FC, Smith AV, McColgan P, Lindemann M, Lipsmeier F, Wild EJ, Dorn J.   +10 more
europepmc   +1 more source

Executive Impairment in Huntington's Disease: Insights From a Systematic Review of the Literature

Brain and Behavior, Volume 16, Issue 2, February 2026.
Executive dysfunction in Huntington's disease follows a selective, stage‐dependent pattern, with early deficits in psychomotor speed, cognitive flexibility, inhibition, and working‐memory updating. Progression is associated with broader impairments in planning and attention.
Simone Migliore, Martina Marcaccio, Ilaria Di Pompeo, Massimo Marano, Giuseppe Curcio   +4 more
wiley   +1 more source

The Epidemiology of Huntington's Disease in Iceland.

Eur Neurol
Briem S, Stefansdottir V, Jónsson JJ, Sveinsson O, Sveinsson O.   +4 more
europepmc   +1 more source

Post-Translational Modifications of Huntingtin: Mechanistic Insights and Therapeutic Opportunities in Huntington's Disease. [PDF]

Int J Mol Sci
Zhang X, Zhang S, Wang C.
europepmc   +1 more source

Acute Presentation of Nonpuerperal Uterine Inversion Following a Diagnosis of Uterine Carcinosarcoma: A Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Nonpuerperal uterine inversion (NPUI) due to endometrial carcinosarcoma can present in an acute manner with life‐threatening complications. The rare presentation of uterine inversion outside of the puerperium caused by a malignant etiology, which was further complicated by the urgent need for intervention, makes this case crucial in ...
Aman Kaur More, Sarah Louise Smyth, Ana Sofia Cerdeira, Hooman Soleymani majd   +3 more
wiley   +1 more source

Preliminary observations of glucose metabolism dysregulation in pediatric Huntington's disease. [PDF]

Front Neurol
Graziola F, Danti FR, Penzo M, Spagarino A, Minacapilli E, Moscatelli M, Zibordi F, Mariotti C, Zorzi G.   +8 more
europepmc   +1 more source

Proteomic Analysis of Regulated Dendritic Cell Endosomes Reveals Dynamic Adaptation to Antigen Uptake and Cross‐Presentation

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Phagocytosis of yeast activates recruitment of proteases and trafficking factors from the secretory and endosomal pathways to the IRAP compartment and subsequently phagosomes, promoting cross‐presentation. In the absence of Sec22b, IRAP endosome and phagosome maturation to late endosomes is accelerated.
Alice Senni, Louise Grumbach, Sara Ceccacci, Mathieu Frechin, Nicolas Goudin, Ida Chiara Guerrera, Barbara Bertocci, Peter van Endert   +7 more
wiley   +1 more source