Results 1 to 10 of about 8,943,114 (413)
Wearable sensors in Huntington disease:a pilot study [PDF]
Journal of Huntington's Disease, 2016 Background: The Unified Huntington’s Disease Rating Scale (UHDRS) is the principal means of assessing motor impairment in Huntington disease but is subjective and generally limited to in-clinic assessments.
Bechtel +29 more
core +2 more sources
Huntington disease exacerbates action impulses. [PDF]
Front Psychol, 2023 BackgroundImpulsivity is a common clinical feature of Huntington disease (HD), but the underlying cognitive dynamics of impulse control in this population have not been well-studied.ObjectiveTo investigate the temporal dynamics of action impulse control ...
Shiino S +4 more
europepmc +2 more sources
Did the "Woman in the Attic" in Jane Eyre Have Huntington Disease? [PDF]
Tremor and Other Hyperkinetic Movements, 2015 Background: References to neurologic disorders are frequently found in fictional literature and may precede description in the medical literature. Aim: Our aim was to compare Charlotte Brontë’s depiction of Bertha Mason in Jane Eyre to the ...
Elizabeth A. Coon, Anhar Hassan
doaj +4 more sources
Principles and Practice of Movement Disorders, 2010 Adult-onset Huntington disease, the most common form of this disorder, usually appears in a person's thirties or forties. Early signs and symptoms can include irritability, depression, small involuntary movements, poor coordination, and trouble learning ...
Joseph Jankovic +5 more
semanticscholar +2 more sources
Clinical presentation of juvenile Huntington disease [PDF]
Arquivos de Neuro-Psiquiatria, 2006 OBJECTIVE: To describe the clinical presentation a group of patients with juvenile onset of Huntington disease. METHOD: All patients were interviewed following a structured clinical questioner.
Ruocco Heloísa H. +4 more
doaj +2 more sources
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease [PDF]
Human Molecular Genetics, 2003 An expanded CAG repeat is the underlying genetic defect in Huntington disease, a disorder characterized by motor, psychiatric and cognitive deficits and striatal atrophy associated with neuronal loss.
Elizabeth Slow
openalex +2 more sources
Nature Reviews Disease Primers, 2015 Huntington disease is devastating to patients and their families - with autosomal dominant inheritance, onset typically in the prime of adult life, progressive course, and a combination of motor, cognitive and behavioural features. The disease is caused by an expanded CAG trinucleotide repeat (of variable length) in HTT, the gene that encodes the ...
Bruno Di Muzio
semanticscholar +7 more sources
Predictors of persistence and adherence to deutetrabenazine among patients with Huntington disease or tardive dyskinesia. [PDF]
Ment Health Clin, 2023 Introduction Deutetrabenazine is approved for treatment of Huntington disease (HD)-related chorea and tardive dyskinesia (TD) in adults. Factors associated with deutetrabenazine persistence and adherence are not well understood.
Claassen DO +4 more
europepmc +2 more sources
Suicidal behaviour in huntington disease [PDF]
Eur Psychiatry, 2021 Introduction Huntington Disease (HD) is a genetic, progressive neurodegenerative disorder. Its clinical features include motor dysfunction, cognitive impairments, and psychiatric symptoms.
Freitas R, Valadas M.
europepmc +2 more sources