Results 91 to 100 of about 9,184,817 (390)
PSYCHIATRIC ASPECTS OF HUNTINGTON DISEASE – CASE REPORTS
Zdravniški Vestnik, 2004 Background. Huntington disease occurrs rarely, it can be encountered not only by neurologists and psychiatrists but also by other medical practitioners. Its characteristic features are involuntary movements, cognitive disorders and gradual development of
Mirela Batta +2 more
doaj
Drug Delivery, 2018 Neurodegenerative movement disorders mainly include Parkinson’s disease, atypical parkinsonisms, Huntington disease, and hereditary ataxia. Riluzole is the only drug approved by the US Food and Drug Administration for amyotrophic lateral sclerosis.
Jia Liu, Lu-Ning Wang
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2020 Mitochondrial deregulation has gained increasing support as a pathological mechanism in Huntington’s disease (HD), a genetic-based neurodegenerative disorder caused by CAG expansion in the HTT gene. In this study, we thoroughly investigated mitochondrial-
Carla Lopes +18 more
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Longitudinal Beta-Binomial Modeling using GEE for Over-Dispersed Binomial Data [PDF]
, 2016 Longitudinal binomial data are frequently generated from multiple questionnaires and assessments in various scientific settings for which the binomial data are often overdispersed.
Long, Jeffrey D. +2 more
core +1 more source
International Guidelines for the Treatment of Huntington's Disease
Frontiers in Neurology, 2019 The European Huntington's Disease Network (EHDN) commissioned an international task force to provide global evidence-based recommendations for everyday clinical practice for treatment of Huntington's disease (HD). The objectives of such guidelines are to
A. Bachoud-Lévi +16 more
semanticscholar +1 more source
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Advanced Science, EarlyView.Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu +17 more
wiley +1 more source
Levodopa-responsive chorea: A review
Annals of Indian Academy of Neurology, 2020 Background: Chorea is one of the disabling movement disorders, and the number of drugs which can treat this disorder effectively is limited. Tetrabenazine and deutetrabenazine are the two drugs approved by the US-FDA for the treatment of chorea ...
Mark Farrenburg, Harsh V Gupta
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Oxidative stress parameters in plasma of Huntington's disease patients, asymptomatic Huntington's disease gene carriers and healthy subjects : a cross-sectional study [PDF]
, 2007 BACKGROUND : Animal data and postmortem studies suggest a role of oxidative stress in the Huntington's disease (HD), but in vivo human studies have been scarce.
Babić, Tomislav +5 more
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The Role of Microglia and Astrocytes in Huntington’s Disease
Frontiers in Molecular Neuroscience, 2019 Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease. HD patients present with movement disorders, behavioral and psychiatric symptoms and cognitive decline.
T. Palpagama +3 more
semanticscholar +1 more source
Pediatric Neurology Briefs, 1989 The positron-emission tomography (PET) findings in a seven year old girl with the juvenile form of Huntington's disease are described from the Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, Montreal, Canada.
openaire +3 more sources