Results 191 to 200 of about 127,576 (299)

Vitamin C Transport Deficiency Alters Striatal Dopamine Gene Expression and Metabolism in YAC128 Huntington Disease Mice. [PDF]

Genes Brain Behav
Tienda AA, Harrison FE, Wilcox JM.
europepmc   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker, Andrew F. James, Svetlana Mastitskaya   +2 more
wiley   +1 more source

Randomized Trial of Telegenetic Counseling for Gene Testing in Huntington Disease. [PDF]

Neurol Clin Pract
Hall DA, Rosenbaum M, Hawkins J, Ouyang B, Cooper C, Patel N.   +5 more
europepmc   +1 more source

The central benefit of physiologically induced ketogenic states

The Journal of Physiology, EarlyView.
Abstract figure legend This review describes the association between ketogenic states induced by physiological interventions such as fasting or aerobic exercise, exogenous ketone supply and ketogenic diets, as well as increased cognition through increased activity of brain‐derived neurotrophic factor (BDNF).
Antonia Giacco, Giuseppe Petito, Rosalba Senese, Maria Moreno, Assunta Lombardi, Antonia Lanni, Pieter de Lange   +6 more
wiley   +1 more source

Poly ADP-ribose signaling is dysregulated in Huntington disease. [PDF]

Proc Natl Acad Sci U S A
Maiuri T, Bazan CB, Harding RJ, Begeja N, Kam TI, Byrne LM, Rodrigues FB, Warner MM, Neuman K, Mansoor M, Badiee M, Dasovich M, Wang K, Thompson LM, Leung AKL, Andres SN, Wild EJ, Dawson TM, Dawson VL, Arrowsmith CH, Truant R.   +20 more
europepmc   +1 more source

Enviromimetics: From exercise mimetics to cognitomimetics in the quest for enhanced brain health and cognition

The Journal of Physiology, EarlyView.
Abstract figure legend A schematic diagram outlining the concept of enviromimetics, and the subclasses of exercise mimetics, epimimetics and cognitomimetics. The rationale is that environmental stimulation and lifestyle factors, including physical activity and cognitive stimulation, have shown beneficial effects across a range of human conditions ...
Anthony J. Hannan
wiley   +1 more source

Protocol considerations for multigenerational blinding of preimplantation genetic testing for a monogenic condition for Huntington disease: a case report. [PDF]

F S Rep
Raine S, Siegel DR, Rabkina L, Nassab P, Cervero A, Martinez-Conejero JA, Elfman H, Polotsky AJ.   +7 more
europepmc   +1 more source

Recent optical approaches for anatomical and functional dissection of neuron–astrocyte circuitry

The Journal of Physiology, EarlyView.
Abstract figure legend This review summarises novel optical approaches to deciphering structural and functional wiring diagrams of neuron–astrocyte circuits in the brain. There are three groups: the anatomical proximity assay, transsynaptic viral tracing and the functional connection assay. The FRET‐based neuron–astrocyte proximity assay allows mapping
Yoshiki Hatashita, Takafumi Inoue
wiley   +1 more source

Improving the Clinical Diagnostic Criteria for Genetically Confirmed Adult-Onset Huntington Disease: Considering Nonmotor Presentations. [PDF]

Neurol Clin Pract
Considine CM, Eddy CM, Frank SA, Kostyk SK, Oosterloo M, Killoran A, Furr Stimming E, Dose M, Cruickshank T, Bird TD, Vetter L, Arnesen A, Valvano J, Lange HW, Claassen DO.   +14 more
europepmc   +1 more source

How breathing disrupts vision: hyperventilation‐induced hypocapnia impairs oculomotor responses in resting humans

The Journal of Physiology, EarlyView.
Abstract figure legend Hypocapnic hyperventilation reduced end‐tidal carbon dioxide partial pressure and middle cerebral artery mean velocity, and impaired oculomotor response by modulating visual fixation and anti‐saccadic control. Hyperventilation itself also impaired anti‐saccadic control.
Yusei Yoshimura, Tomoka Sagawa, Seiji Ono, Takeshi Nishiyasu, Naoto Fujii   +4 more
wiley   +1 more source