Results 191 to 200 of about 9,201,564 (391)
Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles [PDF]
Benjamin R. Underwood+10 more
openalex +1 more source
ABSTRACT Background The onset and pattern of progression of swallowing impairment in HD remain poorly understood. The Swallowing Disturbance Questionnaire (SDQ) has proven useful in assessing dysphagia across various neurological conditions, but its use in HD remains largely unexplored. Objectives To evaluate swallowing difficulties in HD using the SDQ
Japleen Kaur+3 more
wiley +1 more source
Huntington disease mutation in Venezuela: age of onset, haplotype analyses and geographic aggregation [PDF]
Irene Paradisi+2 more
openalex +1 more source
Neural Mechanisms of Object Location Memory in Huntington's Disease
ABSTRACT Background Object‐location memory impairment in Huntington's disease (HD) occurs from premanifest period and declines as HD progresses, however, pathogenesis of object‐location memory is unknown. The striatum and hippocampus are affected in HD, functionally interacting allowing intact object‐location memory.
Yifat Glikmann‐Johnston+4 more
wiley +1 more source
Understanding the psychiatric prodrome of Huntington disease [PDF]
Adam Rosenblatt
openalex +1 more source
Adult‐Onset Dystonia‐Parkinsonism: Do Not Forget SERAC1
Movement Disorders Clinical Practice, EarlyView.
Giulia Scacciatella+15 more
wiley +1 more source
Abstract Background Breakdown of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) in basal ganglia cells through hydrolysis of diesteric bonds, primarily by PDE10A and PDE1B, is essential for normal human movement. While biallelic loss‐of‐function variants in PDE10A are known to cause hyperkinetic movement disorders, the ...
Tomer Poleg+21 more
wiley +1 more source
Predictability of Age at Onset in Huntington Disease in the Dutch Population
Anneke Maat‐Kievit+8 more
openalex +1 more source
Calcium Homeostasis and Mitochondrial Dysfunction in Striatal Neurons of Huntington Disease [PDF]
Dmitry Lim+6 more
openalex +1 more source