Results 221 to 230 of about 127,576 (299)

Digital assessment of speech in Huntington disease. [PDF]

Front Neurol
Nunes AS, Pawlik M, Mishra RK, Waddell E, Coffey M, Tarolli CG, Schneider RB, Dorsey ER, Vaziri A, Adams JL.   +9 more
europepmc   +1 more source

Ratoon Season Rice Reduces Methane Emissions by Limiting Acetic Acid Transport to the Rhizosphere and Inhibiting Methanogens

Advanced Science, Volume 13, Issue 8, 9 February 2026.
This study finds that the interaction between ABA‐OsCIPK2‐OsSWEET1A reduces the allocation of methane producing bacteria carbon source (acetic acid) content to the rhizosphere soil of ratoon season rice, thereby reducing methane emissions. Abstract Rice paddies are a major, persistent source of atmospheric methane (CH4), emission rates depend on the ...
Jingnan Zou, Hailong Xu, Bin Qin, Chaojie Lan, Jinying Li, Bianhong Zhang, Huabin Zhang, Chunlin Guo, Hongfei Chen, Zhongming Fang, Quanzhi Zhao, Wenfei Wang, Changxun Fang, Zhixing Zhang, Wenxiong Lin   +14 more
wiley   +1 more source

Safety and Efficacy of Deutetrabenazine at High versus Lower Daily Dosages in the ARC-HD Study to Treat Chorea in Huntington Disease. [PDF]

CNS Drugs
Frank S, Testa CM, Goldstein J, Kayson E, Leavitt BR, Oakes D, O'Neill C, Whaley J, Gross N, Chaijale N, Barash S, Gordon MF, Huntington Study Group/ARC-HD Investigators and Coordinators.   +12 more
europepmc   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Integrative determination of atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington disease. [PDF]

Nat Commun
Bagherpoor Helabad M, Matlahov I, Kumar R, Daldrop JO, Jain G, Weingarth M, van der Wel PCA, Miettinen MS.   +7 more
europepmc   +1 more source

Brd4 BD1 Domain Antagonism of MS436 Preserves Blood‐Brain Barrier Integrity via Rnf43/β‐Catenin Signaling Pathway

Advanced Science, Volume 13, Issue 7, 3 February 2026.
MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.
Chenxiao Li, Xiaochen Zhang, Jiangwei Xia, Shuang Liu, Yushan Du, Sihan Li, Shukui Zhang, Yong Zhang, Fen Ji, Jianwei Jiao, Jingjing Zhang   +10 more
wiley   +1 more source

Racial Disparities in Time to Huntington Disease Diagnosis in North America: An ENROLL-HD Analysis. [PDF]

Neurol Clin Pract
Mendizabal A, Ogilvie AC, Bordelon Y, Perlman SL, Brown A.   +4 more
europepmc   +1 more source

Long‐term amyloid PET and MRI outcomes in a menopausal hormone therapy trial

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Associations of short‐term use of menopausal hormone therapy (mHT) with Alzheimer's disease (AD) and structural magnetic resonance imaging (MRI) biomarkers were investigated 10 years after an mHT trial. METHODS Recently menopausal women with good cardiovascular health were randomized to oral conjugated equine estrogens (oCEE) or ...
Kejal Kantarci, Firat Kara, Nirubol Tosakulwong, Angela J. Fought, Christopher G. Schwarz, Matthew L. Senjem, June Kendall‐Thomas, Paul Min, Val J. Lowe, Clifford R. Jack, Ekta Kapoor, Julie A. Fields, Kent R. Bailey, Taryn T. James, Laura Faubion, Rogerio A. Lobo, JoAnn E. Manson, Lubna Pal, Dustin B. Hammers, Eliot A. Brinton, Michael Malek‐Ahmadi, Marcelle I. Cedars, Frederick N. Naftolin, Nanette Santoro, Virginia M. Miller, Sherman M. Harman, N. Maritza Dowling, Carey E. Gleason   +27 more
wiley   +1 more source

Age- and disease-related autophagy impairment in Huntington disease: New insights from direct neuronal reprogramming. [PDF]

Aging Cell
Luo C, Yang J.
europepmc   +1 more source

An RCAF Erk in England and North Africa, 1941-1945 The War Story of Leading Aircraftman Kenneth Frank Huntington [PDF]

, 2015
Matt Huntington
core   +1 more source