Results 21 to 30 of about 9,364,929 (305)
Experimental and Molecular Medicine, 2019 Huntington disease is a neurodegenerative condition for which there is no cure to date. Activation of AMP-activated protein kinase has previously been shown to be beneficial in in vitro and in vivo models of Huntington’s disease. Moreover, a recent cross-
A. Sanchis +6 more
semanticscholar +1 more source
Neural Regeneration Research, 2015 MicroRNA-124 contributes to neurogenesis through regulating its targets, but its expression both in the brain of Huntington′s disease mouse models and patients is decreased.
Tian Liu +3 more
doaj +1 more source
Suicidal behaviour in huntington disease
European Psychiatry, 2021 Introduction Huntington Disease (HD) is a genetic, progressive neurodegenerative disorder. Its clinical features include motor dysfunction, cognitive impairments, and psychiatric symptoms.
R. Mota Freitas, M.T. Valadas
doaj +1 more source
Huntington’s Disease Pathogenesis: Two Sequential Components
Journal of Huntington's Disease, 2021 Historically, Huntington’s disease (HD; OMIM #143100) has played an important role in the enormous advances in human genetics seen over the past four decades.
E. Hong +10 more
semanticscholar +1 more source
Anesthetic management of a patient with Huntington's chorea -A case report- [PDF]
Korean Journal of Anesthesiology, 2013 Huntington's chorea is a rare hereditary disorder of the nervous system. It is inherited as an autosomal dominant disorder and is characterized by progressive chorea, dementia and psychiatric disturbances.
Jong-Man Kang +5 more
doaj +1 more source
Systemic Air Embolism Associated with Pleural Pigtail Chest Tube Insertion
Case Reports in Pulmonology, 2016 Pleural pigtail catheter placement is associated with many complications including pneumothorax, hemorrhage, and chest pain. Air embolism is a known but rare complication of pleural pigtail catheter insertion and has a high risk of occurrence with ...
Emad Alkhankan +3 more
doaj +1 more source
Brain Growth in Children at Risk for Huntington Disease
Pediatric Neurology Briefs, 2012 Researchers at the University of Iowa and Washington University, St Louis, MO, studied the effect of the mutant Huntington gene (mHTT) on measures of growth in children at risk for Huntington disease (HD).
J Gordon Millichap
doaj +1 more source
Digital Biomarkers, 2017 Background: Clinician rating scales and patient-reported outcomes are the principal means of assessing motor symptoms in Parkinson disease and Huntington disease.
Jamie L. Adams +11 more
semanticscholar +1 more source
Huntington disease: a single-gene degenerative disorder of the striatum
Dialogues in Clinical Neuroscience, 2016 Huntington disease (HD) is an autosomal dominant, neurodegenerative disorder with a primary etiology of striatal pathology. The Huntingtin gene (HTT) has a unique feature of a DNA trinucleotide (triplet) repeat, with repeat length ranging from 10 to 35 ...
P. Nopoulos
semanticscholar +1 more source
Basal Ganglia and Thalamic Infarction
Pediatric Neurology Briefs, 1997 The signs, symptoms, and radiographic findings in 36 children, newborns to 13 years of age, with ischemic infarctions of the basal ganglia, internal capsule, or thalamus are reported from the University of Texas Southwestern Medical Center, Dallas, TX.
J Gordon Millichap
doaj +1 more source