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Huntington disease is a neurodegenerative condition for which there is no cure to date. Activation of AMP-activated protein kinase has previously been shown to be beneficial in in vitro and in vivo models of Huntington’s disease. Moreover, a recent cross-
A. Sanchis +6 more
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MicroRNA-124 contributes to neurogenesis through regulating its targets, but its expression both in the brain of Huntington′s disease mouse models and patients is decreased.
Tian Liu +3 more
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Suicidal behaviour in huntington disease
Introduction Huntington Disease (HD) is a genetic, progressive neurodegenerative disorder. Its clinical features include motor dysfunction, cognitive impairments, and psychiatric symptoms.
R. Mota Freitas, M.T. Valadas
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Huntington’s Disease Pathogenesis: Two Sequential Components
Historically, Huntington’s disease (HD; OMIM #143100) has played an important role in the enormous advances in human genetics seen over the past four decades.
E. Hong +10 more
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Anesthetic management of a patient with Huntington's chorea -A case report- [PDF]
Huntington's chorea is a rare hereditary disorder of the nervous system. It is inherited as an autosomal dominant disorder and is characterized by progressive chorea, dementia and psychiatric disturbances.
Jong-Man Kang +5 more
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Systemic Air Embolism Associated with Pleural Pigtail Chest Tube Insertion
Pleural pigtail catheter placement is associated with many complications including pneumothorax, hemorrhage, and chest pain. Air embolism is a known but rare complication of pleural pigtail catheter insertion and has a high risk of occurrence with ...
Emad Alkhankan +3 more
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Brain Growth in Children at Risk for Huntington Disease
Researchers at the University of Iowa and Washington University, St Louis, MO, studied the effect of the mutant Huntington gene (mHTT) on measures of growth in children at risk for Huntington disease (HD).
J Gordon Millichap
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Background: Clinician rating scales and patient-reported outcomes are the principal means of assessing motor symptoms in Parkinson disease and Huntington disease.
Jamie L. Adams +11 more
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Huntington disease: a single-gene degenerative disorder of the striatum
Huntington disease (HD) is an autosomal dominant, neurodegenerative disorder with a primary etiology of striatal pathology. The Huntingtin gene (HTT) has a unique feature of a DNA trinucleotide (triplet) repeat, with repeat length ranging from 10 to 35 ...
P. Nopoulos
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Basal Ganglia and Thalamic Infarction
The signs, symptoms, and radiographic findings in 36 children, newborns to 13 years of age, with ischemic infarctions of the basal ganglia, internal capsule, or thalamus are reported from the University of Texas Southwestern Medical Center, Dallas, TX.
J Gordon Millichap
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