Results 31 to 40 of about 127,477 (200)

Associations of Plasma Glutamatergic Metabolites with Alpha Desynchronization during Cognitive Interference and Working Memory Tasks in Asymptomatic Alzheimer’s Disease

Cells
Electroencephalogram (EEG) studies have suggested compensatory brain overactivation in cognitively healthy (CH) older adults with pathological beta-amyloid(Aβ42)/tau ratios during working memory and interference processing.
Vincent Sonny Leong, Jiaquan Yu, Katherine Castor, Abdulhakim Al-Ezzi, Xianghong Arakaki, Alfred Nji Fonteh   +5 more
doaj   +1 more source

Bilateral Striatal Syndromes

Pediatric Neurology Briefs, 1993
The clinical manifestations and outcome in 13 patients with bilateral basal ganglia lesions and neurological dysfunction are reported from the Child Neurology Unit, Vall D’Hebron University Hospital, Barcelona, Spain.
J Gordon Millichap
doaj   +1 more source

Circulating hsa-miR-323b-3p in Huntington's Disease: A Pilot Study

Frontiers in Neurology, 2021
The momentum of gene therapy in Huntington's disease (HD) deserves biomarkers from easily accessible fluid. We planned a study to verify whether plasma miRNome may provide useful peripheral “reporter(s)” for the management of HD patients. We performed an
Michela Ferraldeschi, Silvia Romano, Simona Giglio, Carmela Romano, Emanuele Morena, Rosella Mechelli, Viviana Annibali, Martina Ubaldi, Maria Chiara Buscarinu, Renato Umeton, Renato Umeton, Renato Umeton, Renato Umeton, Gabriele Sani, Gabriele Sani, Andrea Vecchione, Marco Salvetti, Marco Salvetti, Giovanni Ristori, Giovanni Ristori   +19 more
doaj   +1 more source

Oxidative stress parameters in plasma of Huntington's disease patients, asymptomatic Huntington's disease gene carriers and healthy subjects : a cross-sectional study [PDF]

, 2007
BACKGROUND : Animal data and postmortem studies suggest a role of oxidative stress in the Huntington's disease (HD), but in vivo human studies have been scarce.
Babić, Tomislav, Hećimović, Silva, Klepac, Nataša, Klepac, Ratimir, Relja, Maja, Trkulja, Vladimir   +5 more
core   +1 more source

The Role of Differentially Expressed miRNAs and Potential miRNA-mRNA Regulatory Network in Prostate Cancer Progression and Metastasis [PDF]

, 2020
Purpose: Aberrant expression of microRNAs (miRNAs) has been discovered in prostate cancer progression however their function is not well understood, thereby further investigation is required to understand the importance of underlying mechanisms and their
Arisan, E.D., Arisan, E.D., Freitas, I.L., Freitas, I.L., Pazoki, K., Pazoki, K., Rahim, S., Rahim, S., Uysal Onganer, P., Uysal Onganer, P.   +9 more
core   +1 more source

Experience of experimental simulation of Huntington’s disease

Анналы клинической и экспериментальной неврологии, 2017
Huntingtons disease (HD) is an autosomal dominant neurodegenerativedisease characterized by choreic hyperkinesia, cognitivedecline, behavioral disorders, and progressive neuronaldeath affecting primarily the striatum.
A. V. Stavrovskaya, D. N. Voronkov, N. G. Yamshchikova, A. S. Ol’shanskiy, R. M. Khudoerkov, S. N. Illarioshkin   +5 more
doaj   +1 more source

Performance of the 12-item WHODAS 2.0 in prodromal Huntington disease [PDF]

, 2015
ACKNOWLEDGEMENTS We thank the PREDICT-HD sites, the study participants, the National Research Roster for Huntington Disease Patients and Families, the Huntington’s Disease Society of America and the Huntington Study Group.
Downing, Nancy, Kim, Ji-In, Long, Jeffrey D, Miedzybrodzka, Zofia Helena, Mills, James A, Paulsen, Jane S, PREDICT-HD Investigators And Coordinators Of The Huntington Study Group, Williams, Janet K   +7 more
core   +1 more source

A case report of juvenile Huntington disease

Journal of Pediatric and Neonatal Individualized Medicine, 2017
Huntington disease (HD) is a progressive neurodegenerative disorder, characterized by autosomal dominant inheritance, movement disorder, dementia, and behavioural disturbances.
Anita Choudhary, Priyanka Minocha, Sadasivan Sitaraman   +2 more
doaj   +1 more source

A Randomized, Double-blind, Placebo-Controlled Study of Latrepirdine in Patients With Mild to Moderate Huntington Disease. [PDF]

, 2013
BACKGROUND Latrepirdine is an orally administered experimental small molecule that was initially developed as an antihistamine and subsequently was shown to stabilize mitochondrial membranes and function, which might be impaired in Huntington disease ...
DE MICHELE, GIUSEPPE, European Huntington's Disease Network, HORIZON Investigators of the Huntington Disease Study Group, SACCA', FRANCESCO, SALVATORE, ELENA   +4 more
core   +1 more source

Palliative Care in Huntington Disease: Personal Reflections and a Review of the Literature

Tremor and Other Hyperkinetic Movements, 2017
Background Huntington disease is a fatal, autosomal dominant, neurodegenerative disorder manifest by the triad of a movement disorder, behavioral disturbances, and dementia.
Christopher G. Tarolli, Amy M. Chesire, Kevin M. Biglan   +2 more
doaj   +1 more source