Results 101 to 110 of about 5,858 (232)
Ethanol and methanol can improve huperzine A production from endophytic Colletotrichum gloeosporioides ES026. [PDF]
PLoS ONE, 2013 Huperzine A (HupA) is a plant alkaloid that is of great interest as a therapeutic candidate for the treatment of Alzheimer's disease. However, the current production of HupA from plants in large quantity is unsustainable because the plant resource is ...
Xin-Mei Zhao +7 more
doaj +1 more source
European Journal of Organic Chemistry, Volume 28, Issue 8, February 24, 2025.There are continuous efforts to improve total syntheses of natural products, particularly their sustainability, such as developing effective chiral pool approaches relying on a wide spectrum of natural chirons, including (−)‐sclareol as one of the most useful natural chirons.
Ayyoub Selka +5 more
wiley +1 more source
Formulation and characterization of an apigenin-phospholipid phytosome (APLC) for improved solubility, in vivo bioavailability, and antioxidant potential [PDF]
, 2016 The apigenin-phospholipid phytosome (APLC) was developed to improve the aqueous solubility, dissolution, in vivo bioavailability, and antioxidant activity of apigenin.
Anand, Sridhar +5 more
core +2 more sources
Donepezil increases resistance to induced seizures in a mouse model of Dravet syndrome
Annals of Clinical and Translational Neurology, 2019 De novo loss‐of‐function mutations in SCN1A are the main cause of Dravet syndrome, a catastrophic encephalopathy characterized by recurrent early‐life febrile seizures, a number of other afebrile seizure types that are often refractory to treatment, and ...
Jennifer C. Wong +2 more
doaj +1 more source
A review study on medicinal plants affecting amnesia through cholinergic system [PDF]
, 2012 Neurotransmitter modification is an important method for the treatment of memory loss or amnesia. Cholinomimetic drugs, particularly, acetylcholine esterase inhibitors are the mainstream in pharmacotherapy of amnesia. Donepezil, tacrine, galantamine, and
Baradaran, Azar. +3 more
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Octodrine: New Questions and Challenges in Sport Supplements [PDF]
, 2018 This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).Background: Octodrine is the
Ademiluyi +21 more
core +3 more sources
Journal of Chemistry, Volume 2025, Issue 1, 2025.Alzheimer’s disease (AD) is a significant concern in the elderly, characterized by impaired cholinergic transmission,decreased choline acetyltransferase activity and increased acetylcholinesterase (AChE) activity, resulting in reduced acetylcholine levels.
Yinsheng Yang +9 more
wiley +1 more source
Huperzine A: is it an effective disease-modifying drug for Alzheimer’s disease?
Frontiers in Aging Neuroscience, 2014 Alzheimer's disease (AD) is a progressive neurodegenerative disorder for which there is no cure. Huperzine A (HupA) is a natural inhibitor of acetylcholinesterase (AChE) derived from the Chinese folk medicine Huperzia serrata (Qian Ceng Ta).
Zhong Ming eQian, Ya eKe
doaj +1 more source
Pb2+, Cu2+, Zn2+, Mg2+ and Mn2+ reduce the affinities of flavone, genistein and kaempferol for human serum albumin in vitro [PDF]
, 2011 Flavone (Fl), genistein (Gen) and kaempferol (Kol) were studied for their affinities towards human serum albumin (HSA) in the presence and absence of Pb2+,Cu2+,Zn2+,Mg2+ and Mn2+.
Liu Chunxi +6 more
core +1 more source