Results 81 to 90 of about 5,858 (232)

Synthetic approaches towards the Lycopodium alkaloids [PDF]

, 2014
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/63704The Lycopodium alkaloids are a structurally diverse group of natural products isolated from Lycopodium with important biological effects for the potential treatment of cancer and severe
Balañà, Marta, Bonjoch i Sesé, Josep, Bradshaw, Ben, Luque Corredera, Carlos, Saborit Villarroya, Gisela   +4 more
core  

Intranasal delivery of Huperzine A to the brain using lactoferrin-conjugated N-trimethylated chitosan surface-modified PLGA nanoparticles for treatment of Alzheimer’s disease

International Journal of Nanomedicine, 2018
Background Safe and effective delivery of therapeutic drugs to the brain is important for successful therapy of Alzheimer’s disease (AD). Purpose To develop Huperzine A (HupA)-loaded, mucoadhesive and targeted polylactide-co-glycoside (PLGA ...
Qingqing Meng, Aiping Wang, Hongchen Hua, Ying Jiang, Yiyun Wang, Hongjie Mu, Zi-Xin Wu, Kaoxiang Sun   +7 more
semanticscholar   +1 more source

Reference gene selection for real‐time quantitative PCR assays in different tissues of Huperzia serrata based on full‐length transcriptome sequencing

Plant Direct, 2021
Huperzia serrata (H. serrata) produces various types of effective lycopodium alkaloids, especially Huperzine A (HupA), which is a promising drug for the treatment of Alzheimer's disease.
Yanping Fu, Fei Niu, Hui Jia, Yanli Wang, Bin Guo, Yahui Wei   +5 more
doaj   +1 more source

In Vitro Propagation, Huperzine A Content and Antioxidant Activity of Three Genotypic Huperzia serrata

Plants, 2021
Huperzia serrata is a traditional herb and endangered Chinese medicinal material, which has attracted much attention due to its production of Huperzine A (HupA). In vitro propagation of H.
Yan Yang, L. Dai, Decai Wu, Limin Dong, Yisheng Tu, Jian-Kun Xie, Xiangdong Luo   +6 more
semanticscholar   +1 more source

Acetylation‐Deacetylation‐Driven Natural Product Biosynthesis

ChemistryEurope, Volume 3, Issue 4, July 14, 2025.
This review summarizes the role of acetylation‐deacetylation in natural product biosynthesis, including acetylation followed by deacetylation after several biosynthetic steps, acetylation‐mediated rearrangement, acetylation‐triggered elimination, and the acetylation cycle as a regulatory mechanism. These processes are vital for the formation of complex
Huibin Wang, Ikuro Abe
wiley   +1 more source

Synthetic biology for medical biomaterials

Interdisciplinary Medicine, Volume 3, Issue 4, July 2025.
Synthetic biology platform has been utilized to produce a variety of medical biomaterials (MBMs), such as polylactic acid (PLA), polyhydroxyalkanoates (PHAs), hyaluronic acid (HA), collagen (COL), poly(β‐malic acid) (PMLA), poly‐γ‐glutamic acid (γ‐PGA), alginate (ALG), chitosan (CS), bacterial cellulose (BC), and antimicrobial peptides (AMPs).
Tao Xu, Xiao‐Yun Huang, Jin‐Wei Dao, Da Xiao, Dai‐Xu Wei   +4 more
wiley   +1 more source

The Role of Natural Products in Pharmacotherapy of Alzheimer’s Disease [PDF]

, 2005
Alzheimer’s disease is characterized by forgetfulness, disturbance in memory and loss of mental abilities. The final outcome of the disease is loss of personality and intellectual functions.
Singh, Amrit Pal
core   +1 more source

Natural Products in Epilepsy—the Present Situation and Perspectives for the Future [PDF]

, 2014
More efficacious and better tolerated treatments for epilepsy are clearly needed. Complementary and alternative medicine (CAM) has a long history of use in certain parts of the world and has gained increasing interest over the last decades in Western ...
Ekstein, Dana, Schachter, Steven C.
core   +1 more source

Evaluating dietary quality and dietary inflammatory potential in cognitive impairment patients in China

Alzheimer's &Dementia, Volume 21, Issue 6, June 2025.
Abstract INTRODUCTION Diet plays a critical role in the prevention and treatment of cognitive impairment, yet dietary intake in patients with cognitive impairment in China remains insufficiently studied. METHODS A 25‐item semi‐quantitative food frequency questionnaire was used in a national online survey in China.
Dongsheng Bian, Furu Liang, Yong You, Xianfeng Li, Hua Hu, Huali Wang, Huayan Liu, Lu Shen, Oumei Cheng, Qiumin Qu, Shunliang Xu, Weihong Kuang, Qinying Ma, Xiaoping Pan, Xinyu Zhao, Yang Zhang, Yifeng Du, Ying Xu, Yong'an Sun, Zhengluan Liao, Jintao Wang, Jianping Li, Jinwen Xiao, Haixia Li, Xinyi Xie, Zike Yun, Jieli Geng, Wenwei Cao, Nan Zhi, Rujing Ren, Hengge Xie, Gang Wang, representing ADC   +32 more
wiley   +1 more source

Metabolomic and metagenomic analyses elucidate the role of intercropping in mitigating continuous cropping challenges in tobacco. [PDF]

Front Plant Sci
IntroductionCrop rotation of tobacco with other crops could effectively break the negative impact of continuous tobacco cropping, but the mechanisms of intercropping system effects on tobacco, especially on the rhizosphere, are not clear.MethodsIn this ...
Liu M, Xue R, Jin S, Gu K, Zhao J, Guan S, Xie X, Su J, Wang L.   +8 more
europepmc   +2 more sources