Results 151 to 160 of about 82,581 (251)

Mechanisms involved in the electrospray of biological macromolecules [PDF]

, 2011
PhDElectrospray of macro-molecules is of great interest in biomedical research for its finely controlled delivery of molecules. This thesis investigated mechanisms involved in electrospray of biological macromolecules. Hyaluronan, i.e.
Tan, Zhikai
core  

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

Importance of hyaluronan-CD44 interactions in inflammation and tumorigenesis.

, 2008
Hyaluronan is an apparently simple polysaccharide that is responsible for tissue hydration but also stimulates cell proliferation, migration, and differentiation via binding to cell surface receptors, such as CD44.
Skandalis, Spyros S.,, NISHITSUKA K, SKANDALIS SS, PORSCH H, Porsch, Helena,, Nishitsuka, Koichi,, HELDIN P, Heldin, Paraskevi,, KAROUSOU, EVGENIA, Karousou, Eugenia,, BERNERT B, Bernert, Berit,   +11 more
core   +1 more source

Improving periodontal regeneration outcomes with hyaluronic acid: A systematic review and meta‐analysis

Periodontology 2000, EarlyView.
Abstract Objectives To evaluate the clinical and radiographic efficacy of the adjunctive use of hyaluronic acid (HA) in regenerative periodontal surgery for the treatment of intrabony defects. Materials and Methods A systematic search identified randomized controlled trials (RCTs) involving adult patients with intrabony defects who underwent ...
Abdusalam E. Alrmali, Qasim Omer Butt, Rami Kassar, Parham Hazrati, Yousef Amrou, Anton Sculean, Hom‐Lay Wang   +6 more
wiley   +1 more source

Hyaluronan: its potential application in intervertebral disc regeneration

, 2010
Bojiang Shen, Aiqun Wei, Divya Bhargav, Thomas Kishen, Ashish D DiwanOrthopaedic Research Institute, Department of Orthopaedic Surgery, St. George Hospital, The University of New South Wales, Sydney, AustraliaAbstract: Hyaluronan (HA) is a ubiquitous ...
Divya Bhargav, et al, Bojiang Shen, Aiqun Wei   +3 more
core  

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies

The Journal of Physiology, EarlyView.
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu, Rachel E. A. Smyth, Aishwarya Prakash, Thomas Iskratsch   +3 more
wiley   +1 more source

Removal rate of [3H]hyaluronan injected subcutaneously in rabbits

, 1990
Hyaluronan is an important constituent of the extracellular matrix in skin, and recent studies suggest that there is a pool of easily removable ("free") hyaluronan drained by lymph.
J. R. Fraser, U. B. Laurent, R. K. Reed, T. C. Laurent   +3 more
core   +1 more source

Molecular identification of hyaluronate lyase, not hyaluronidase, as an intrinsic hyaluronan-degrading enzyme in Clostridium perfringens strain ATCC 13124

Scientific Reports
Clostridium perfringens, an opportunistic pathogen, produces mu-toxin hyaluronidases including endo-β-N-acetylglucosaminidases (Nags) as a virulence invasion factor.
Tomoya Kumon, Sayoko Oiki, Wataru Hashimoto   +2 more
doaj   +1 more source

The interplay between dynamic regulation of ion‐channel gating and trafficking in cardiac arrhythmogenesis

The Journal of Physiology, EarlyView.
Abstract figure legend Cardiac cellular electrophysiology is modulated by multiple factors, including temperature, extracellular K+, heart rate/pacing frequency, and drugs. These modulators can have distinct effects on ion‐channel gating and transcription/trafficking over time.
Stefan Meier, Anna S. Savchenko, Paul G. A. Volders, Jordi Heijman   +3 more
wiley   +1 more source

Prolonged rod photoresponse and enhanced cone sensitivity in the transgenic mouse retina lacking arrestin and guanylate cyclase activating proteins

The Journal of Physiology, EarlyView.
Abstract figure legend Analyses from mutant mouse retinal explants gives invaluable insights of the photosignaling process in rod and cone photoreceptor cells. A, Illustration of retinal photovoltage recordings. A retinal explant (pink) is placed in a transparent device which has electrodes to monitor transretinal voltage (red and blue circles).
Shinya Sato, Rikard Frederiksen, Alapakkam P. Sampath, Vladimir J. Kefalov   +3 more
wiley   +1 more source