Results 141 to 150 of about 82,581 (251)

Genetic Deficiency of Hyaluronan Synthase 2 in the Developing Limb Mesenchyme Impairs Postnatal Synovial Joint Formation

Biomedicines
Hyaluronan, a key component of the extracellular matrix, plays a crucial role in joint development and maintenance. In order to determine the role of hyaluronan function in joint development and homeostasis, conditional loss-of-function experiments of ...
Yingcui Li, Alexander Tress, Peter Maye, Kemar Edwards, Asiona Findletar, Nathaniel A. Dyment, Yu Yamaguchi, David W. Rowe, Gengyun Le-Chan, Sunny S. K. Chan, Kevin W.-H. Lo   +10 more
doaj   +1 more source

Prenatal Presentation of Muggenthaler‐Chowdhury‐Chioza Syndrome Caused by Compound Heterozygous Variants in HYAL2

Prenatal Diagnosis, EarlyView.
Pauline Planté‐Bordeneuve, Anne‐Cécile Leroy‐Tarissi, Marine Tessarech, Pauline Gras, Anne Dieux‐Coëslier, Morgane Stichelbout, Sonia Bouquillon, Thomas Smol   +7 more
wiley   +1 more source

A film of tuberose polysaccharide supports normal epidermal keratinization by suppressing cytokine release induced by external stimuli

International Journal of Cosmetic Science, EarlyView.
(a) Dry, rough skin has an immature stratum corneum prone to stimuli, triggering IL‐1α/IL‐1ra/IL‐8 release, keratinization defects, reduced ceramide NP/NS and lipids, scaling and poor hydration. (b) TPS forms a flexible reticular film, shielding the SC, lowering cytokines, normalizing differentiation, restoring lipids and improving texture and water ...
Junko Ishikawa, Yuka Yasuda
wiley   +1 more source

Periodontal Treatment Restores Gingival Crevicular Fluid and Serum Periostin Levels

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Background and Aim To investigate the effect of periodontal treatment on periodontal inflammation and periostin levels in patients with severe periodontitis. Methods This study included two groups (periodontitis and periodontally healthy), each comprising 24 individuals.
Aysegul Sarı, Oguzhan Ozcan, Filiz Kaçmaz, Anton Sculean, Alpdogan Kantarci   +4 more
wiley   +1 more source

Lipotoxicity Amplifies IL‐6 Trans‐Signaling in Sinusoidal Endothelial Cells to Promote Endotheliopathy and Liver Injury

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aims Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects approximately 25% of the global population and is a major health concern. Liver sinusoidal endothelial cells (LSECs) undergo morphological and functional alterations during MASLD progression, resulting in endotheliopathy characterized by pro ...
Yasuhiko Ueda, Nao Kawaguchi, Yosuke Inomata, Jun Arima, Mitsuaki Ishida, Yuko Ito, Sang‐Woong Lee, Kohei Taniguchi   +7 more
wiley   +1 more source

Hyaluronan binding by CD44 on T cells

, 2010
CD44 is a transmembrane protein that binds to hyaluronan, a component of the extracellular and pericellular matrices. Hyaluronan supports cell migration and proliferation during embryonic development, wound repair, as well as tumourigenesis. Hyaluronan
Maeshima, Nina Miharu
core   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Distribution of hyaluronan in bull reproductive organs.

, 1994
To study the expression of hyaluronan in male reproductive organs and the origin of seminal plasma hyaluronan, we stained various parts of the bull reproductive tract for hyaluronan using a biotinylated probe derived from cartilage proteoglycan (bHABC).
M Tammi, R Tammi, U M Agren, S Rönkkö
core   +1 more source

Transcriptome Analysis Reveals Distinct Molecular Signatures Between Erosive and Non‐Erosive Oral Lichen Planus

Oral Diseases, EarlyView.
ABSTRACT Objectives To identify molecular mechanisms distinguishing the erosive subtype of oral lichen planus (EOLP) from the non‐erosive subtype (NEOLP) through transcriptomic analysis. Methods We analysed bulk RNA‐seq data from 30 buccal mucosa samples (13 EOLP, 17 NEOLP) using differential expression, Gene Set Enrichment Analysis (GSEA ...
Kisung Sheen, Chaerim Song, Kanghyun Kwon, Seoyeon Kim, Hye‐Ji Park, Man S. Kim   +5 more
wiley   +1 more source

Hyaluronan ion complexes

, 2013
This diploma thesis is focused on the study of physical and chemical properties of hyaluronan and cationic surfactant. As the cationic surfactant Septonex was used.
Cimalová, Jana
core