Results 121 to 130 of about 82,581 (251)
Hyaluronan: From Biomimetic to Industrial Business Strategy
Natural Product Communications, 2011 Hyaluronan (hyaluronic acid) is a naturally occurring polysaccharide of a linear repeating disaccharide unit consisting of β-(1→4)-linked D-glucopyranuronic acid and β-(1→3)-linked 2-acetamido-2-deoxy-D-glucopyranose, which is present in extracellular ...
Erminio Murano +3 more
doaj +1 more source
Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4
Journal of Experimental Medicine, 2002 Low molecular weight fragmentation products of the polysaccharide of Hyaluronic acid (sHA) produced during inflammation have been shown to be potent activators of immunocompetent cells such as dendritic cells (DCs) and macrophages.
C. Termeer +9 more
semanticscholar +1 more source
Phytotherapy Research, EarlyView.Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li +14 more
wiley +1 more source
, 2012 Progression to osteoarthritis OA is a frequent sequela of severe articular fracture, particularly when weight- bearingjoints are involved. Prevention from post-traumatic OA remains a challenge.
黃鐙樂;許弘昌;楊凱?;林峰輝 +1 more
core +1 more source
Evaluating hyaluronan content of pancreatic cancer based on CT texture analysis
Zhongguo aizheng zazhi, 2020 Background and purpose: The increased accumulation of hyaluronan correlates with cancer aggressiveness and chemoresistance. Evaluating hyaluronan content may provide information to individualized management in patients with pancreatic cancer. As an image
解添淞 +3 more
doaj
Dual‐Component Spidroin‐Based Hydrogels: A Mechanically Tunable Platform for 2D and 3D Cell Culture
Small, EarlyView.A dual‐component recombinant spider silk hydrogel platform was developed by combining NT2RepCT with a bioactive vitronectin‐functionalized spidroin domain. The hydrogels self‐assemble under physiological conditions, exhibit tunable mechanical properties, and support 2D and 3D cell culture, providing a versatile platform for mechanobiological studies ...
Sanna Korpela +8 more
wiley +1 more source
Encoding Cell‐Surface Receptor Function Through Glycosylation: Lessons From CD44 [PDF]
ChembiochemCD44 function is not solely determined by its protein sequence, it is dynamically encoded by its glycosylation state. Glycan remodeling generates distinct functional receptor states that regulate ligand recognition, receptor organization, lectin interactions, and signaling.
Payá‐García M +7 more
europepmc +2 more sources
Hyaluronan-Based Nanofibers: Fabrication, Characterization and Application
Polymers, 2019 Nano- and microfibers based on biopolymers are some of the most attractive issues of biotechnology due to their unique properties and effectiveness. Hyaluronan is well-known as a biodegradable, naturally-occurring polymer, which has great potential for ...
P. Snetkov +3 more
semanticscholar +1 more source
Evolutionary Mechanisms of Coagulation Factors in Cetaceans During Aquatic Adaptation
Integrative Zoology, EarlyView.Compared with Bos taurus, T. truncatus showed shorter prothrombin time and thrombin time but prolonged activated partial thromboplastin time, indicating pathway‐specific remodeling of coagulation. Evolutionary analyses identified 18 positively selected genes and accelerated F11 evolution, while functional assays revealed increased coagulation factor ...
Wenjun Lv +4 more
wiley +1 more source
BMC Cancer, 2009 Background Hyaluronan, a tumor promoting extracellular matrix polysaccharide, is elevated in malignant epithelial ovarian tumors, and associates with an unfavorable prognosis.
Heikkinen Anna-Mari +9 more
doaj +1 more source