Results 101 to 110 of about 82,581 (251)
Developmental Cell, 2019 High-molecular-weight hyaluronan, a major component of the extracellular matrix, is anti-oncogenic, whereas low-molecular-weight hyaluronan is pro-oncogenic, though the mechanisms underlying the size-dependent opposite bioactivities of hyaluronan remain ...
Takuya Ooki +4 more
semanticscholar +1 more source
Review of articular cartilage repair techniques and their application in the horse
Equine Veterinary Journal, EarlyView.Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton +2 more
wiley +1 more source
Hyaluronan and phospholipids in boundary lubrication
, 2012 Hyaluronan has been found to play an important role in boundary lubrication in joints, but model experiments have shown that free hyaluronan is reluctant to stay between surfaces.
Wang, Min, +4 more
core +1 more source
Matrix Biology, 2019 The malignant phenotype of various cancers is linked to enhanced expression of hyaluronan, a pro-angiogenic glycosaminoglycan whose expression is suppressed by 4-methylumbelliferone (4-MU), a non-toxic oral agent used as a dietary supplement to improve ...
Theodoros Karalis +7 more
semanticscholar +1 more source
Deregulation of hyaluronan synthesis, degradation and binding promotes breast cancer
, 2013 Clinical and experimental data indicate that hyaluronan accumulates in breast cancer compared with normal breast epithelium, which correlates to poor prognosis.
Kozlova, Inna, +5 more
core +1 more source
Interactions between CD44 and hyaluronan in leukocyte trafficking
Frontiers in Immunology, 2015 Recruitment of leukocytes from the bloodstream to inflamed tissues requires a carefully regulated cascade of binding interactions between adhesion molecules on leukocytes and endothelial cells. Adhesive interactions between CD44 and hyaluronan have been
Braedon eMcDonald +2 more
doaj +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Sepsis‐induced acute lung injury (ALI) remains challenging to treat, with conventional anti‐inflammatory therapies offering limited efficacy. The lymphatic system is crucial for removing edema and inflammatory mediators, and its impairment can exacerbate lung injury.
He Wang +4 more
wiley +1 more source
Macromolecular Rapid Communications, EarlyView.This work demonstrates successful gamma‐radiation‐induced grafting of N‐hydroxyethyl acrylamide onto poly[(R)‐3‐hydroxybutyrate], producing substantial changes in material properties. Grafting generated a biphasic, less crystalline structure with enhanced thermal stability, elongation (65%), toughness (378% increase), and exceptional water uptake (610 ...
Cole Walchle +5 more
wiley +1 more source
Turnover of hyaluronan in the rabbit pleural space
, 1992 Hyaluronan influences lung fluid balance. The clearance of lung hyaluronan by way of the pulmonary lymphatics and the pleural space is increased when fluid flux into the interstitium is increased.
U. B. Laurent +4 more
core +1 more source
PLoS ONE, 2019 Certain bacterial species target the polysaccharide glycosaminoglycans (GAGs) of animal extracellular matrices for colonization and/or infection. GAGs such as hyaluronan and chondroitin sulfate consist of repeating disaccharide units of uronate and amino
Sayoko Oiki +5 more
doaj +1 more source