Results 81 to 90 of about 56,873 (208)
International Journal of Cosmetic Science, EarlyView.Cannabis sativa root‐derived extracellular vesicle‐like nanoparticles (CA‐NPs) were isolated from adventitious root cultures and subjected to physicochemical characterization. Upon UVB exposure, keratinocytes exhibited increased ROS generation, apoptosis and MAPK activation, leading to oxidative stress and skin damage.
Dong Ho Bak +5 more
wiley +1 more source
Paclitaxel-loaded hyaluronan solid nanoemulsions for enhanced treatment efficacy in ovarian cancer
, 2017 Joo-Eun Kim, Young-Joon Park College of Pharmacy, Ajou University, Suwon City, Republic of Korea Abstract: Paclitaxel-loaded hyaluronan solid nanoemulsions (PTX-HSNs) were successfully fabricated for the delivery of PTX to improve ovarian cancer ...
Park YJ, Kim JE
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Journal of Periodontal Research, EarlyView.The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag +6 more
wiley +1 more source
Essential role of hyaluronan in mouse hippocampal development
This thesis is about the essential role that hyaluronan plays in the extracellular matrix of the central nervous system. In our study we used plasmids encoding hyaluronidase enzyme to disrupt the extracellular matrix.
Bradnick, Carolyn
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, 1995 The present study was carried out to explore the mechanisms underlying hyaluronan-induced sperm motility. We demonstrate for the first time the enhanced cellular protein phosphorylation in hyaluronic acid stimulated cauda spermatozoa.
Datta, K. +2 more
core +1 more source
Hyaluronic acid: A novel approach in regenerative/reconstructive periodontal therapy?
Periodontology 2000, EarlyView.Abstract Background Although hyaluronic acid (HA) has long been used for many medical applications, only in recent years has it gained greater popularity in the field of periodontics because of its biological effects during wound healing. Even today, most clinicians are not aware that more than one type of HA exists and that the extent of its ...
Andrea Pilloni +7 more
wiley +1 more source
Regulation of hyaluronan biosynthesis and clinical impact of excessive hyaluronan production
, 2019 The tightly regulated biosynthesis and catabolism of the glycosaminoglycan hyaluronan, as well as its role in organizing tissues and cell signaling, is crucial for the homeostasis of tissues.
Lin, Chun-Yu, +9 more
core +1 more source
Understanding exosomes in facial esthetics and skin aging
Periodontology 2000, EarlyView.Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron +3 more
wiley +1 more source
Hyaluronan-amino acids interactions
, 2021 The presented dissertation focuses on non-covalent interactions of hyaluronan of different molecular weights (9–1540 kDa) with basic (oligo)-amino acids (especially arginine) and the antimicrobial peptide cecropin B.
Jugl, Adam
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Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies
The Journal of Physiology, EarlyView.Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu +3 more
wiley +1 more source