Results 81 to 90 of about 48,338 (197)

Transcriptome Analysis Reveals Distinct Molecular Signatures Between Erosive and Non‐Erosive Oral Lichen Planus

open access: yesOral Diseases, EarlyView.
ABSTRACT Objectives To identify molecular mechanisms distinguishing the erosive subtype of oral lichen planus (EOLP) from the non‐erosive subtype (NEOLP) through transcriptomic analysis. Methods We analysed bulk RNA‐seq data from 30 buccal mucosa samples (13 EOLP, 17 NEOLP) using differential expression, Gene Set Enrichment Analysis (GSEA ...
Kisung Sheen   +5 more
wiley   +1 more source

Evaluating hyaluronan content of pancreatic cancer based on CT texture analysis

open access: yesZhongguo aizheng zazhi, 2020
Background and purpose: The increased accumulation of hyaluronan correlates with cancer aggressiveness and chemoresistance. Evaluating hyaluronan content may provide information to individualized management in patients with pancreatic cancer. As an image
解添淞   +3 more
doaj  

The High‐Intensity Zone: A Dynamic Inflammatory Hub in Lumbar Disc Degeneration

open access: yesOrthopaedic Surgery, EarlyView.
The HIZ, a dynamic inflammatory hub in lumbar disc degeneration, links inflammation‐degeneration‐pain; integrating advanced diagnostics and targeted therapies offers precise management for discogenic low back pain. ABSTRACT The lumbar intervertebral disc high‐intensity zone (HIZ), a focal hyperintensity within the annulus fibrosus on T2‐weighted ...
Qi Zhou   +6 more
wiley   +1 more source

Understanding exosomes in facial esthetics and skin aging

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron   +3 more
wiley   +1 more source

Two Case Reports of Intravenous Leiomyomatosis with Hyaluronan Expression

open access: yesCase Reports in Obstetrics and Gynecology, 2018
Intravenous leiomyomatosis (IVL) is a rare benign neoplasm. Herein, we describe two cases of IVL at different levels of progression. The tumor in Case 1 was extensive, invading the right atrium after a hysterectomy for a uterine myoma.
Haruhisa Konishi   +8 more
doaj   +1 more source

Improving periodontal regeneration outcomes with hyaluronic acid: A systematic review and meta‐analysis

open access: yesPeriodontology 2000, EarlyView.
Abstract Objectives To evaluate the clinical and radiographic efficacy of the adjunctive use of hyaluronic acid (HA) in regenerative periodontal surgery for the treatment of intrabony defects. Materials and Methods A systematic search identified randomized controlled trials (RCTs) involving adult patients with intrabony defects who underwent ...
Abdusalam E. Alrmali   +6 more
wiley   +1 more source

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu   +3 more
wiley   +1 more source

Genetic Deficiency of Hyaluronan Synthase 2 in the Developing Limb Mesenchyme Impairs Postnatal Synovial Joint Formation

open access: yesBiomedicines
Hyaluronan, a key component of the extracellular matrix, plays a crucial role in joint development and maintenance. In order to determine the role of hyaluronan function in joint development and homeostasis, conditional loss-of-function experiments of ...
Yingcui Li   +10 more
doaj   +1 more source

The interplay between dynamic regulation of ion‐channel gating and trafficking in cardiac arrhythmogenesis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cardiac cellular electrophysiology is modulated by multiple factors, including temperature, extracellular K+, heart rate/pacing frequency, and drugs. These modulators can have distinct effects on ion‐channel gating and transcription/trafficking over time.
Stefan Meier   +3 more
wiley   +1 more source

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