Results 71 to 80 of about 56,873 (208)
Recombinant expression, purification and characterization of human hyaluronidases
, 2007 Hyaluronidases and their substrate, hyaluronic acid, are known to play a role in signal transduction events directly correlated with tumor growth and cell migration. Yet correlations with disease progression are controversial due to scarce information on
Hofinger, Edith
core +1 more source
Hyaluronan and proximal tubular cell migration
, 2004 Hyaluronan and proximal tubular cell migration.BackgroundThe ubiquitous polysaccharide hyaluronan has been associated with both acute renal injury and progressive renal disease.
Phillips, A O +9 more
core +2 more sources
Membrane‐type I metalloproteinase (MT1‐MMP): A key modifier of extracellular matrix microenvironment
The FEBS Journal, EarlyView.MT1‐MMP: A cellular microenvironment modifier. MT1‐MMP is a major cellular microenvironment modifier, maintaining collagen homeostasis by degrading excess collagen (A), creating a migration path in motile cells such as cancer cells (B), modulating local microenvironmental signaling by cleaving transmembrane receptors (C), and destroying tissue ...
Yoshifumi Itoh, Masaki Inada
wiley +1 more source
Proteolytic remodelling of the extracellular matrix by pericytes
The FEBS Journal, EarlyView.Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Mechanisms involved in the electrospray of biological macromolecules
, 2011 PhDElectrospray of macro-molecules is of great interest in biomedical research for its finely controlled delivery of molecules. This thesis investigated mechanisms involved in electrospray of biological macromolecules. Hyaluronan, i.e.
Tan, Zhikai
core
Hyaluronan Synthase 3 Regulates Hyaluronan Synthesis in Cultured Human Keratinocytes
, 2002 Three human hyaluronan synthase genes (HAS1, HAS2, and HAS3) have been cloned, but the functional differences between these HAS genes remains obscure. The purpose of this study was to examine which of the HAS genes are selectively regulated in epidermis.
Takahashi, Yoshito +15 more
core +1 more source
Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma
The FEBS Journal, EarlyView.IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture +3 more
wiley +1 more source
Matrix Viscoelasticity: The Overlooked Architect of Solid Tumour Evolution
Organ Medicine, EarlyView.
Ruixi Huang, Yupeng Guan
wiley +1 more source
A review of skin microbiome and new challenges to cosmetic microbiome‐friendly formulations
International Journal of Cosmetic Science, EarlyView.Microbiome‐friendly concepts offer new perspectives for a healthy relationship between cosmetic use and the skin microbiome, especially the interaction of non‐biotic cosmetic ingredients with the skin, requiring further studies to clarify the dynamics between the skin microbiome and different classes of cosmetic ingredients.
Yasmin Rosa Santos +3 more
wiley +1 more source
Hyaluronan micro- and nanoparticles
, 2013 The aim of this thesis was to prepare hyaluronic acid micro- and nanoparticles based on electrostatic interactions with oppositely charged molecules. Following parameters were monitored: correlation function behavior, the particle size and zeta potential
Mourycová, Jana
core +1 more source