Results 91 to 100 of about 82,581 (251)
, 1997 In many but not all cases, malignant mesothelioma is associated with an elevated content of hyaluronan in pleural fluid. The hyaluronan-producing mesothelioma has not yet been immunohistochemically characterized; therefore, the purpose of this study was ...
Thylén, A +3 more
core +1 more source
SPERM SELECTION WITH HYALURONAN AND BLASTOCYST DEVELOPMENT AFTER ICSI
Zdravniški Vestnik, 2018 Background. Selection of mature sperm for intracytoplasmic sperm injection (ICSI) has recently been made possible by hyaluronan, a naturally occurring substance found in the cumulus cells.
Lili Bačer Kermavner +4 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi +9 more
wiley +1 more source
Dissecting the role of hyaluronan synthases in the tumor microenvironment
The FEBS Journal, 2019 The tumor microenvironment is becoming a crucial factor in determining the aggressiveness of neoplastic cells. The glycosaminoglycan hyaluronan is one of the principal constituents of both the tumor stroma and the cancer cell surfaces, and its ...
A. Passi +3 more
semanticscholar +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu +3 more
wiley +1 more source
Intracellular Localization of Hyaluronan in Proliferating Cells
, 1999 Hyaluronan is a high molecular weight glycosaminoglycan found in the extracellular matrix of many tissues, where it is believed to promote cell migration and proliferation. It was recently shown that hyaluronan-dependent pericellular matrix formation is
Stephen P. Evanko, Thomas N. Wight
core +1 more source
Harnessing bacterial extracellular vesicles for bone and cartilage organoids
BMEMat, EarlyView.This review presents bacterial extracellular vesicles (BEVs) as programmable bioactive regulators for bone and cartilage organoids by delivering functional cargos that modulate skeletal remodeling. It highlights key engineering strategies and future directions to advance next‐generation organoid models for bone aging related diseases.
Han Liu +8 more
wiley +1 more source
IQGAP1 regulates hyaluronan-mediated fibroblast motility and proliferation
, 2012 IQGAP1, an essential scaffolding protein, forms a complex with the hyaluronan receptor CD44. In this study, we have examined the importance of IQGAP1 for hyaluronan-mediated fibroblast migration and proliferation.
Kozlova, Inna, +4 more
core +1 more source
Hyaluronan, a Crucial Regulator of Inflammation
Frontiers in Immunology, 2014 Hyaluronan (HA), a major component of the extracellular matrix (ECM), plays a key role in regulating inflammation. Inflammation is associated with accumulation and turnover of hyaluronan polymers by multiple cell types. Increasingly through the years, HA
Aaron C Petrey, Carol A. de la Motte
doaj +1 more source