Results 41 to 50 of about 82,581 (251)

Reaction of superoxide radicals with glycosaminoglycan chloramides: a kinetic study. [PDF]

, 2013
Hypochlorous acid and its acid-base counterpart, hypochlorite ions, produced under inflammatory conditions, may produce chloramides of glycosaminoglycans, perhaps through the binding of myeloperoxidase directly to the glycosaminoglycans.
Parsons, BJ, Sibanda, S., Heyes, D. J.; id_orcid, Sibanda, S, Parsons, B. J., Paterson, A. W J, Paterson, AW, Heyes, DJ   +7 more
core   +1 more source

High Sensitivity Method to Estimate Distribution of Hyaluronan Molecular Sizes in Small Biological Samples Using Gas-Phase Electrophoretic Mobility Molecular Analysis

International Journal of Cell Biology, 2015
Hyaluronan is a negatively charged polydisperse polysaccharide where both its size and tissue concentration play an important role in many physiological and pathological processes. The various functions of hyaluronan depend on its molecular size.
Lan Do, Christen P. Dahl, Susanne Kerje, Peter Hansell, Stellan Mörner, Ulla Lindqvist, Anna Engström-Laurent, Göran Larsson, Urban Hellman   +8 more
doaj   +1 more source

Low Molecular Mass Myocardial Hyaluronan in Human Hypertrophic Cardiomyopathy

Cells, 2019
During the development of hypertrophic cardiomyopathy, the heart returns to fetal energy metabolism where cells utilize more glucose instead of fatty acids as a source of energy.
Christina E. Lorén, Christen P. Dahl, Lan Do, Vibeke M. Almaas, Odd R. Geiran, Stellan Mörner, Urban Hellman   +6 more
doaj   +1 more source

<i>Rosa rugosa</i> Root Extract as a Functional Food Ingredient, Mitigating UVB-Induced Skin Aging Through MAPK/AP-1 and AGE-RAGE Pathway Modulation. [PDF]

Food Sci Nutr
Rosa rugosa root extract (RR‐r) attenuated UVB‐induced wrinkle formation and collagen degradation while improving skin hydration. Its photoprotective effects were associated with modulation of MAPK/AP‐1 and AGE‐RAGE signaling. ABSTRACT Rosa rugosa root extract (RR‐r) has been used in East Asian medicine to treat metabolic disorders, including diabetes ...
Gu MJ, Yoo G, Lee SH, Park HY, Kim Y, Kim D, Ha SK.   +6 more
europepmc   +2 more sources

Presence of hyaluronan in lung alveoli in severe Covid-19: An opening for new treatment options?

Journal of Biological Chemistry, 2020
Severe coronavirus disease 2019 (Covid-19) is characterized by inflammation of the lungs with increasing respiratory impairment. In fatal Covid-19, lungs at autopsy have been filled with a clear liquid jelly.
U. Hellman, M. Karlsson, A. Engström-Làurent, S. Cajander, Luiza Dorofte, C. Ahlm, C. Laurent, A. Blomberg   +7 more
semanticscholar   +1 more source

Hyaluronan in the Airways

, 2004
In the airway, hyaluronan is not only found in the submucosal, connective tissue compartment, but also on the luminal, ciliated surface of the airway epithelium, as shown by histochemistry of human and ovine tracheal sections using a biotinylated ...
Salathe, Matthias, MATTHIAS SALATHE, ROSANNA FORTEZA, Conner, Gregory E, Forteza, Rosanna, GREGORY E. CONNER   +5 more
core   +1 more source

Studies on the sperm reservoir of the pig oviduct [PDF]

, 2003
During sperm transport in the female pig a proportion of spermatozoa are arrested, often for 24 h or more, in a particular segment of the utero-tubal junction (UTJ) and the adjacent tubal isthmus, where a sperm reservoir (SR) is built up.
Tienthai, Paisan
core   +1 more source

Hyaluronan synthase 2–mediated hyaluronan production mediates Notch1 activation and liver fibrosis

Science Translational Medicine, 2019
Hepatic stellate cells activated by hyaluronan synthase 2–mediated hyaluronan and Notch1 promote liver fibrosis, identifying a potential target. HAlting liver fibrosis Hepatic stellate cells (HSCs) play a key role in liver fibrosis, a process marked by ...
Yoon Mee Yang, M. Noureddin, Cheng Liu, Koichiro Ohashi, S. Y. Kim, Divya Ramnath, E. Powell, M. Sweet, Y. Roh, I-Fang Hsin, N. Deng, Zhen-Qiu Liu, Jiu-Rong Liang, E. Mena, D. Shouhed, R. Schwabe, D. Jiang, Shelly C. Lu, P. Noble, E. Seki   +19 more
semanticscholar   +1 more source

Hyaluronan in medical practice [PDF]

, 2016
Hyaluronan is the major extracellular matrix glycosaminoglycan polymer present in vertebrate tissues, with a molar mass that can reach several megaDaltons. It is particularly prominent in the matrix of tissues undergoing rapid turnover, in fetal tissues,
Valachová, Katarína, VOLPI, Nicola, Stern, Robert, Šoltés, Ladislav   +3 more
core   +1 more source

Phospholipids and Hyaluronan: From Molecular Interactions to Nano- and Macroscale Friction

Colloids and Interfaces, 2022
Phospholipids and hyaluronan are two key biomolecules that contribute to the excellent lubrication of articular joints. Phospholipids alone and in combination with hyaluronan have also displayed low friction forces on smooth surfaces in micro- and ...
Sixuan Li, Lubica Macakova, Piotr Bełdowski, Per M. Claesson, Andra Dėdinaitė   +4 more
doaj   +1 more source