Results 31 to 40 of about 82,581 (251)

Hyaluronic acid (hyaluronan): a review

, 2018
Hyaluronic acid (HA) is a high molecular weight biopolysacharide, discovered in 1934, by Karl Meyer and his assistant, John Palmer in the vitreous of bovine eyes.
J. Nečas, L. Bartošíková, P. Brauner, J. Kolar   +3 more
semanticscholar   +1 more source

Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling

Nature Communications, 2020
In recent years, exploration of the brain extracellular space (ECS) has made remarkable progress, including nanoscopic characterizations. However, whether ECS precise conformation is altered during brain pathology remains unknown.
F. Soria, C. Paviolo, E. Doudnikoff, Marie-Laure Arotcarena, Antony Lee, N. Danné, A. Mandal, P. Gosset, B. Dehay, L. Groc, L. Cognet, E. Bézard   +11 more
semanticscholar   +1 more source

Hyaluronan biology: A complex balancing act of structure, function, location and context

Matrix Biology, 2019
Cell-matrix interactions are fundamental to many developmental, homeostatic, immune and pathologic processes. Hyaluronan (HA), a critical component of the extracellular matrix (ECM) that regulates normal structural integrity and development, also ...
S. Garantziotis, R. Savani
semanticscholar   +1 more source

Cell Energy Metabolism and Hyaluronan Synthesis

Journal of Histochemistry and Cytochemistry, 2020
Hyaluronan (HA) is a linear glycosaminoglycan (GAG) of extracellular matrix (ECM) synthesized by three hyaluronan synthases (HASes) at the plasma membrane using uridine diphosphate (UDP)-glucuronic acid (UDP-GlcUA) and UDP-N-acetylglucosamine (UDP-GlcNAc)
I. Caon, Arianna Parnigoni, M. Viola, E. Karousou, A. Passi, D. Vigetti   +5 more
semanticscholar   +1 more source

Hyaluronan-Based Gel Promotes Human Dental Pulp Stem Cells Bone Differentiation by Activating YAP/TAZ Pathway

Cells, 2021
Background: Hyaluronans exist in different forms, accordingly with molecular weight and degree of crosslinking. Here, we tested the capability to induce osteogenic differentiation in hDPSCs (human dental pulp stem cells) of three hyaluronans forms ...
M. La Noce, A. Stellavato, V. Vassallo, M. Cammarota, L. Laino, V. Desiderio, V. Del Vecchio, G. F. Nicoletti, V. Tirino, G. Papaccio, C. Schiraldi, G. Ferraro   +11 more
semanticscholar   +1 more source

Role of hyaluronan and hyaluronan-binding proteins in human asthma.

, 2022
BackgroundThe characteristics of human asthma are chronic inflammation and airway remodeling. Hyaluronan, a major extracellular matrix component, accumulates during inflammatory lung diseases, including asthma.
Xie, Ting, Jiang, Dianhua, Liang, Jiurong, Ingram, Jennifer, Jung, Yoosun, Noble, Paul W, Church, Tony, Kraft, Monica, Degan, Simone, Leonard, Maura   +9 more
core   +1 more source

Hyaluronan Mediated Motility Receptor (HMMR) Encodes an Evolutionarily Conserved Homeostasis, Mitosis, and Meiosis Regulator Rather than a Hyaluronan Receptor

Cells, 2020
Hyaluronan is an extracellular matrix component that absorbs water in tissues and engages cell surface receptors, like Cluster of Differentiation 44 (CD44), to promote cellular growth and movement.
Zheng-Cheng He, L. Mei, Marisa Connell, C. Maxwell   +3 more
semanticscholar   +1 more source

Preparation of Hyaluronic Acid Oligosaccharides by Enzymatic Method and Its Transdermal Absorption Activity

Shipin gongye ke-ji, 2022
To investigate the transdermal absorption activity of hyaluronic acid oligosaccharides, hyaluronic acid oligosaccharides were prepared by enzymatic degradation of hyaluronic acid using hyaluronic acid lyase, and the hyaluronic acid oligosaccharides were ...
Huining LI, Jingliang ZHANG, Gen YANG, Xiaolu JIANG   +3 more
doaj   +1 more source

Derivatized hyaluronan for gels and nanochemically patterned surfaces

, 2002
In: Hyaluronan - Chemical Biochemical and Biological Aspects, vol. 1, Eds. Kennedy, Phillips, Williams and Hascall, Woodhead Publishing Ltd.
D. PASQUI, Gemma Leone, Daniela Pasqui, BARBUCCI, ROLANDO, Rolando Barbucci, LEONE, GEMMA   +5 more
core   +2 more sources

The Influence of Hofmeister Series Ions on Hyaluronan Swelling and Viscosity

Molecules, 2008
The dissolution of hyaluronan in water leads to its degradation, and as a resultits molecular weight decreases. The degradation of hyaluronan is mainly influenced bytemperature, solution composition, and also its pH.
Vladimír Velebný, Alena Pokopcová, Lenka Gřundělová, Marián Lehocký, Júlia Varhaníková, AleÅ¡ Mráček   +5 more
doaj   +1 more source