Results 121 to 130 of about 20,638 (257)

Evaluating The Effect of Melatonin on HAS2, and PGR expression, as well as Cumulus Expansion, and Fertility Potential in Mice

Cell Journal, 2018
Objective Infertility is a worldwide health problem which affects approximately 15% of sexually active couples. One of the factors influencing the fertility is melatonin.
Maryam Ezzati , Leila Roshangar, Jafar Soleimani, Nahid karimian   +3 more
doaj   +1 more source

Cerebellar Cortex, Purkinje Cell Layer [PDF]

, 2008
This report contains a summary of expression patterns for genes that are enriched in the Purkinje cell layer (CBXpu) of the cerebellum. All data is derived from the Allen Brain Atlas (ABA) in situ hybridization mouse project.
Allen Institute for Brain Science, Angela L. Guillozet-Bongaarts, Emily M. Wright, Lydia L. Ng   +3 more
core   +2 more sources

Increased HA/CD44/TGFβ signaling implicates in renal fibrosis of a Col4a5 mutant Alport mice

Molecular Medicine
X-linked Alport syndrome (XLAS) caused by X-linked COL4A5 gene mutation is a hereditary disease that affects mainly the kidney. XLAS patients, especially males whose single copy of the COL4A5 gene is disrupted, suffer from a life-threatening renal ...
Yantao Bao, Weiqing Wu, Jiyun Lin, Yuankai Yang, Sheng Lin, Jindi Su, Yueyuan Qin, Baojiang Wang, Shan Duan   +8 more
doaj   +1 more source

Investigation of Hyaluronan Synthase 2 and CD44 immune reactivity as a biomarker to predict Progesterone-Resistant Endometrial Hyperplasia without atypia: A retrospective case-control study

Indian Journal of Pathology and Microbiology
Background/Aims: In our study, the effect of hyaluronan synthase 2 (HAS2) and CD44 immunoreactivity as a predictive biomarker in the prediction of progesterone-resistant endometrial hyperplasia (EH) cases without atypia was investigated.
Emine Boybay, Remzi Atilgan, Şehmus Pala, Tuncay Kuloğlu, Gökhan Artaş   +4 more
doaj   +1 more source

Importance of hyaluronan biosynthesis and degradation in cell differentiation and tumor formation

Brazilian Journal of Medical and Biological Research, 2003
Hyaluronan is an important connective tissue glycosaminoglycan. Elevated hyaluronan biosynthesis is a common feature during tissue remodeling under both physiological and pathological conditions.
P. Heldin
doaj   +1 more source

Differential regulation and expression of hyaluronan synthases in human articular chondrocytes, synovial cells and osteosarcoma cells [PDF]

, 2001
Anneliese D. Recklies, Chantal White, Lee I. Melching, Peter J. Roughley   +3 more
openalex   +1 more source

Clinicopathological Role of Serum-Derived Hyaluronan-Associated Protein (SHAP)-Hyaluronan Complex in Endometrial Cancer

Obstetrics and Gynecology International, 2011
The role of hyaluronan (HA), serum-derived HA-associated protein (SHAP)-HA complex and hyaluronan synthase (HAS) in endometrial carcinomas was investigated.
Hiromitsu Yabushita, Keita Iwasaki, Kouhei Kanyama, Yukihiko Obayashi, Lisheng Zhuo, Naoki Itano, Koji Kimata, Akihiko Wakatsuki   +7 more
doaj   +1 more source

P6217Global expression profiling identifies a novel hyaluronan synthases 2 gene in the pathogenesis of lower extremity varicose vein [PDF]

, 2018
Chia‐Ti Tsai, Chia‐Sheng Hsieh, Yizhe Chen, Juey‐Jen Hwang, Eric Y. Chuang, I‐Hui Wu   +5 more
openalex   +1 more source

Dual inhibition of FAS and HAS2/3 by 4-MU in Realgar-Coptis chinensis unveils a metabolic checkpoint for liver cancer therapy

Natural Products and Bioprospecting
Modern pharmacology has found that both Realgar and Coptis chinensis can induce apoptosis in tumor cells, and traditional Chinese medicine theory suggests the possibility of combining the two, however, the specific mechanisms involved have not been ...
Songtao Wu, Yingying Wang, Denghui Deng, Guohua Zheng, Hanxiang Mei, Cong Wang, Xiang Zheng, Chun Gui, Fei Liao, Meixian Xiang   +9 more
doaj   +1 more source

Nanoparticles Containing Hyaluronan Acid and Astragalus Polysaccharides for Treating Osteoarthritis

International Journal of Polymer Science, 2019
The pathogeny of osteoarthritis (OA) is very complicated and still is one of the difficulties in a treating procedure. Here, we constructed nanoparticles using hyaluronan acid (HA) and astragalus polysaccharides (APS) for OA therapy.
Gongbiao Lu, Lin Du, Jishou Lu, Liuzhong Jin   +3 more
doaj   +1 more source