Results 121 to 130 of about 20,143 (217)

Dual inhibition of FAS and HAS2/3 by 4-MU in Realgar-Coptis chinensis unveils a metabolic checkpoint for liver cancer therapy

Natural Products and Bioprospecting
Modern pharmacology has found that both Realgar and Coptis chinensis can induce apoptosis in tumor cells, and traditional Chinese medicine theory suggests the possibility of combining the two, however, the specific mechanisms involved have not been ...
Songtao Wu, Yingying Wang, Denghui Deng, Guohua Zheng, Hanxiang Mei, Cong Wang, Xiang Zheng, Chun Gui, Fei Liao, Meixian Xiang   +9 more
doaj   +1 more source

Nanoparticles Containing Hyaluronan Acid and Astragalus Polysaccharides for Treating Osteoarthritis

International Journal of Polymer Science, 2019
The pathogeny of osteoarthritis (OA) is very complicated and still is one of the difficulties in a treating procedure. Here, we constructed nanoparticles using hyaluronan acid (HA) and astragalus polysaccharides (APS) for OA therapy.
Gongbiao Lu, Lin Du, Jishou Lu, Liuzhong Jin   +3 more
doaj   +1 more source

Decreased expression of hyaluronan synthase and loss of hyaluronan-rich cells in the anterior tibial fascia of the rat model of chemotherapy-induced peripheral neuropathy. [PDF]

Pain Rep, 2023
Wang R, Matsuoka Y, Sue N, Nakatsuka K, Tsuboi C, Morimatsu H.   +5 more
europepmc   +1 more source

Localisation and endocrine control of hyaluronan synthase (HAS) 2, HAS3 and CD44 expression in sheep granulosa cells [PDF]

, 2016
A. A. Fouladi-Nashta, Adamia, Allegrucci, Baerwald, Bodevin-Authelet, Camenisch, Campbell, Campbell, Deroo, El Maradny, Erickson, Fortune, Freudenberger, G. M. Hartshorne, Galluzzo, Hall, Hettinger, Hunter, Itano, Itano, Itano, Jacob, Jain, Juengel, Koehler, Kosaki, Kultti, Laurent, Lee, Luo, Manna, Marei, Marei, Marzioni, Miyake, Miyake, Moriarty, Necas, Nykopp, Nykopp, Ohta, Ohta, Perry, Perry, Pettersson, R. Chavoshinejad, Raheem, Rilla, Robinson, Sainio, Saito, Scaramuzzi, Schoenfelder, Silva, Stern, Tempel, Tienthai, Toole, Toole, Toole, Tsonis, Ulbrich, W. F. A. Marei, Watson, Weigel, Zhao   +65 more
core   +1 more source

An engineered hyaluronan synthase: characterization for recombinant human hyaluronan synthase 2 Escherichia coli.

The Journal of biological chemistry, 2004
The Class I hyaluronan synthase (HAS) is a unique glycosyltransferase synthesizing hyaluronan (HA), a polysaccharide composed of GlcUA and GlcNAc, by using one catalytic domain that elongates two different monosaccharides. As for the synthetic mechanism, there are two alternative manners for the sugar elongation process.
Hiroko, Hoshi, Hiroaki, Nakagawa, Susumu, Nishiguchi, Kazumichi, Iwata, Kenichi, Niikura, Kenji, Monde, Shin-Ichiro, Nishimura   +6 more
openaire   +1 more source

CPAP-induced airway hyper-reactivity in mice is modulated by hyaluronan synthase-3. [PDF]

Pediatr Res, 2022
Mayer CA, Ganguly A, Mayer A, Pabelick CM, Prakash YS, Hascall VC, Midura RJ, Cali V, Flask CA, Erokwu BO, Martin RJ, MacFarlane PM.   +11 more
europepmc   +1 more source

Histochemical structure and immunolocalisation of the hyaluronan system in the dromedary oviduct [PDF]

, 2015
Abdel-Aleem A. El-Saba, Abe, Accogli, Ali A. Fouladi-Nashta, Apichela, Aruffo, Avil�s, Bergqvist, Buhi, Crater, Csoka, Dougherty, Edelstam, Hawk, Ismail, Itano, Lepperdinger, Lesley, Marei, Marei, McCourt, Menezo, Menzel, Nieder, Ohno-Nakahara, Omnia Mohey-Elsaeed, Parrish, Ponglowhapan, Prehm, Raheem, Shimada, Skidmore, Skidmore, Spicer, Srikandakumar, Stern, Stern, Teixeira Gomes, Termeer, Tienthai, Tienthai, Tienthai, Toole, Toyokawa, Ulbrich, Underhill, Waleed F. A. Marei, Wang, Weigel, Whittingham, Xu   +50 more
core   +2 more sources

The effect of the intracervical administration of follicle stimulating hormone or luteinizing hormone on the levels of hyaluronan, COX2 and COX2 mRNA in the cervix of the nonpregnant ewe [PDF]

, 2016
Khalid, M, Leethongdee, S, Scaramuzzi, R J   +2 more
core   +1 more source

An Engineered Hyaluronan Synthase [PDF]

Journal of Biological Chemistry, 2004
Hiroko Hoshi, Hiroaki Nakagawa, Susumu Nishiguchi, Kazumichi Iwata, Kenichi Niikura, Kenji Monde, Shin-Ichiro Nishimura   +6 more
openaire   +1 more source

A Connecting Link between Hyaluronan Synthase 3-Mediated Hyaluronan Production and Epidermal Function. [PDF]

Int J Mol Sci, 2022
Ota Y, Yoshida H, Endo Y, Sayo T, Takahashi Y.   +4 more
europepmc   +1 more source