Results 141 to 150 of about 280,731 (250)

Hyaluronan synthase 3 mediated oncogenic action through forming inter-regulation loop with tumor necrosis factor alpha in oral cancer

OncoTarget, 2017
Hyaluronan (HA) is a major extracellular matrix component. However, its role and mediation in oral cancer remains elusive. Hyaluronan synthase 3 (HAS3), involved in pro-inflammatory short chain HA synthesis, was the predominant synthase in oral cancer ...
Y. Kuo, W. Fang, Cheng-Chih Huang, S. Tsai, Yi-Ching Wang, Chih-Li Yang, Li‐Wha Wu   +6 more
semanticscholar   +1 more source

Evaluating The Effect of Melatonin on HAS2, and PGR expression, as well as Cumulus Expansion, and Fertility Potential in Mice

Cell Journal, 2018
Objective Infertility is a worldwide health problem which affects approximately 15% of sexually active couples. One of the factors influencing the fertility is melatonin.
Maryam Ezzati , Leila Roshangar, Jafar Soleimani, Nahid karimian   +3 more
doaj   +1 more source

Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing. [PDF]

, 2017
Fibrotic diseases contribute to 45% of deaths in the industrialized world, and therefore a better understanding of the pathophysiological mechanisms underlying tissue fibrosis is sorely needed.
Amatucci, Aldo, Anderson, Daniel G, Brenner, David, Burkly, Linda C, Cameron, Thomas O, Cao, Lizhi, Dalkilic-Liddle, Isin, Duffield, Jeremy, Hamann, Stefan, Hossbach, Markus, Kauffman, Kevin J, Kisseleva, Tatiana, Koteliansky, Victor, Mir, Faryal F, Novobrantseva, Tatiana, Reynolds, Taylor, Vollmann, Elisabeth H   +16 more
core   +2 more sources

Hyaluronan Synthase of Chlorella Virus PBCV-1

Science, 1997
Sequence analysis of the 330-kilobase genome of the virus PBCV-1 that infects a chlorella-like green algae revealed an open reading frame, A98R, with similarity to several hyaluronan synthases. Hyaluronan is an essential polysaccharide found in higher animals as well as in a few pathogenic bacteria. Expression of the A98R
Paul L. DeAngelis, James L. Van Etten, James L. Van Etten, Dwight E. Burbank, Dwight E. Burbank, Wei Jing, Wei Jing, Michael V. Graves, Michael V. Graves   +8 more
openaire   +3 more sources

Effect of red ginseng NaturalGEL on skin aging

Journal of Ginseng Research, 2020
Background: In aged skin, degradation of collagen fibers, which occupy the majority of the extracellular matrix in the dermis, and changes of aquaporin 3 (AQP3) and skin constituents, such as hyaluronic acid and ceramide, cause wrinkles and decrease skin
Ye Hyang Kim, Hye Rim Park, So Yoon Cha, So Hun Lee, Jung Wung Jo, Jung Nam Go, Kang Hyuk Lee, Su Yeon Lee, Song Seok Shin   +8 more
doaj  

Dissection of the two transferase activities of the Pasteurella multocida hyaluronan synthase: two active sites exist in one polypeptide [PDF]

, 2000
Jing Wei, Paul L. DeAngelis
openalex   +1 more source

Increased HA/CD44/TGFβ signaling implicates in renal fibrosis of a Col4a5 mutant Alport mice

Molecular Medicine
X-linked Alport syndrome (XLAS) caused by X-linked COL4A5 gene mutation is a hereditary disease that affects mainly the kidney. XLAS patients, especially males whose single copy of the COL4A5 gene is disrupted, suffer from a life-threatening renal ...
Yantao Bao, Weiqing Wu, Jiyun Lin, Yuankai Yang, Sheng Lin, Jindi Su, Yueyuan Qin, Baojiang Wang, Shan Duan   +8 more
doaj   +1 more source

Cellular O-Glycome Reporter/Amplification to explore O-glycans of living cells [PDF]

, 2015
Protein O-glycosylation has key roles in many biological processes, but the repertoire of O-glycans synthesized by cells is difficult to determine. Here we describe an approach termed Cellular O-Glycome Reporter/Amplification (CORA), a sensitive method ...
Antonopoulos, A, Cummings, RD, Dell, A, Duong, DM, Haslam, SM, Ju, T, Kudelka, MR, Seyfried, NT, Song, X, Wang, Y   +9 more
core   +1 more source

Glucocorticoids induce a near-total suppression of hyaluronan synthase mRNA in dermal fibroblasts and in osteoblasts: a molecular mechanism contributing to organ atrophy [PDF]

, 2000
Wei Zhang, C. E. Watson, Changsheng Liu, Kevin Jon Williams, Victoria P. Werth   +4 more
openalex   +1 more source

Investigation of Hyaluronan Synthase 2 and CD44 immune reactivity as a biomarker to predict Progesterone-Resistant Endometrial Hyperplasia without atypia: A retrospective case-control study

Indian Journal of Pathology and Microbiology
Background/Aims: In our study, the effect of hyaluronan synthase 2 (HAS2) and CD44 immunoreactivity as a predictive biomarker in the prediction of progesterone-resistant endometrial hyperplasia (EH) cases without atypia was investigated.
Emine Boybay, Remzi Atilgan, Şehmus Pala, Tuncay Kuloğlu, Gökhan Artaş   +4 more
doaj   +1 more source