Results 121 to 130 of about 10,179 (169)

Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis. [PDF]

Matrix Biol, 2016
Li Y, Liang J, Yang T, Monterrosa Mena J, Huan C, Xie T, Kurkciyan A, Liu N, Jiang D, Noble PW.   +9 more
europepmc   +1 more source

Human Keratinocytes Respond to Extracellular UTP by Induction of Hyaluronan Synthase 2 Expression and Increased Hyaluronan Synthesis. [PDF]

J Biol Chem, 2017
Jokela T, Kärnä R, Rauhala L, Bart G, Pasonen-Seppänen S, Oikari S, Tammi MI, Tammi RH.   +7 more
europepmc   +1 more source

How enzymes make the right choice during biosynthesis. [PDF]

Elife
Ramírez AS, Perez C.
europepmc   +1 more source

The Role of Hyaluronan in Keloid and Hypertrophic Scar Pathogenesis and Treatment. [PDF]

Plast Surg (Oakv)
Shah J, Bhatt A, Yu S, Hill KA, Turley E, Symonette CJ.   +5 more
europepmc   +1 more source

Going with the flow: endothelial dysfunction in type 2 diabetes. [PDF]

Function (Oxf)
Dunaway LS.
europepmc   +1 more source

Efficacy of Japanese Maca Powder Against Aging Stress in Human Dermal Fibroblasts. [PDF]

Int J Mol Sci
Dan K, Takanashi K, Kitamura S.
europepmc   +1 more source

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Phosphorylation of Thr328 in hyaluronan synthase 2 is essential for hyaluronan synthesis

Biochemical and Biophysical Research Communications, 2020
Hyaluronan synthase 2 (HAS2) is an integral membrane protein composed of multi-membrane-spanning regions and a large intracellular loop (HAS2-loop). We previously examined the effect of phorbol 12-myristate 13-acetate (PMA) and/or 4-methylumbelliferone (4-MU) on the synthesis of hyaluronan (HA) in human skin fibroblasts and found that TPA and 4-MU have
Takashi Kobayashi, Kosuke Kasai, Tomisato Miura   +2 more
exaly   +3 more sources

Role of hyaluronan and hyaluronan synthase in endometrial cancer

Oncology Reports, 2005
The aim of this study was to determine if the immunohistochemical expression of hyaluronan synthase (HAS) and serum levels of hyaluronan correlate with the clinicopathological manifestations of endometrial carcinoma. Sera were obtained from 59 endometrial cancer patients and 22 post-menopausal healthy women.
Hiromitsu, Yabushita, Tameko, Kishida, Kanako, Fusano, Kouhei, Kanyama, Lisheng, Zhuo, Naoki, Itano, Koji, Kimata, Masayoshi, Noguchi   +7 more
openaire   +2 more sources

Hyaluronan and Hyaluronan Synthases: Potential Therapeutic Targets in Cancer

Current Drug Target -Cardiovascular & Hematological Disorders, 2005
Current models of oncogenesis describe cancer as a progression of genetic mutations in a tumor cell mass. However, tumors are more than a clonal expansion of malignant cells. Tumors are heterogeneous, with a complex 3D structure, analogous to organs comprised of different tissues.
Sophia, Adamia, Christopher A, Maxwell, Linda M, Pilarski   +2 more
openaire   +4 more sources

Quantitative continuous assay for hyaluronan synthase [PDF]

Analytical Biochemistry, 2007
A rapid, continuous, and convenient three-enzyme coupled UV absorption assay was developed to quantitate the glucuronic acid and N-acetylglucosamine transferase activities of hyaluronan synthase from Pasteurella multocida (PmHAS). Activity was measured by coupling the UDP produced from the PmHAS-catalyzed transfer of UDP-GlcNAc and UDP-GlcUA to a ...
Stephen Withers, Lianli Chi, Robert Linhardt   +2 more
exaly   +4 more sources